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Reynosin

Catalog No. TN2149   CAS 28254-53-7

Reynosin has hepatoprotective, and anti-inflammatory effects, it has protective effect against dopamine-induced neuronal cell death, which may be due to the reciprocal up-regulation of E6-associated protein and down-regulation of α±-synuclein protein expression.

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Reynosin Chemical Structure
Reynosin, CAS 28254-53-7
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Biological Description
Chemical Properties
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Description Reynosin has hepatoprotective, and anti-inflammatory effects, it has protective effect against dopamine-induced neuronal cell death, which may be due to the reciprocal up-regulation of E6-associated protein and down-regulation of α±-synuclein protein expression.
In vitro Using flow cytometry and western blot analysis, we determined that Reynosin significantly protected both against cell death from dopamine-induced toxicity in human neuroblastoma SH-SY5Y cells and against the loss of tyrosine hydroxylase (TH)-positive cells in 6-hydroxydopamine (6-OHDA)-lesioned rats (a rodent Parkinson's disease model system). In addition, Reynosin made up-regulation of E6-associated protein expression and down-regulation of the over-expression of α±-synuclein protein in both dopamine-treated SH-SY5Y cells and 6-hydroxydopamine-lesioned rats[1]
Source
Molecular Weight 248.32
Formula C15H20O3
CAS No. 28254-53-7

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

TargetMolReferences and Literature

1. Reynosin protects against neuronal toxicity in dopamine-induced SH-SY5Y cells and 6-hydroxydopamine-lesioned rats as models of Parkinson's disease: Reciprocal up-regulation of E6-AP and down-regulation of α±-synuclein.Brain Res. 2013 Aug 2;1524:54-61.

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Keywords

Reynosin 28254-53-7 Apoptosis Others TNF BCL inhibitor inhibit

 

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