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Search Result

Search Results for " april "

Targets

Angiotensin-converting Enzyme (ACE)

47

Compounds

1

Natural Products

11

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T16731 Rentiapril racemate (Rac)-SA-446,SA-446 racemate,(Rac)-Rentiapril Angiotensin-converting Enzyme (ACE)
Rentiapril racemate (SA-446 racemate) is the racemate of Rentiapril.Rentiapril racemate has anti-inflammatory activity and may be used in glaucoma research.
T1689 Enalapril IMpurity B (+)-N-[1-(S)-Ethoxycarbonxyl-3-phenylpropyl]-L-alanine Others
Enalapril IMpurity B ((+)-N-[1-(S)-Ethoxycarbonxyl-3-phenylpropyl]-L-alanine) is Moexipril intermediate and is the main metabolite of Imidapril.
T6542 Imidapril hydrochloride Novaloc,Imidapril HCl,Tanapril,TA-6366 RAAS
Imidapril hydrochloride (Tanapril) is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 2.6 nM, used for the treatment of hypertension.
T1605 Enalapril MK-421 RAAS , MRP
Enalapril is a dicarbocyl-containing peptide and angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity.
T6340 Enalaprilat Dihydrate MK-422,MK-422 Dihydrate RAAS , Autophagy
Enalaprilat Dihydrate (MK-422 Dihydrate) （IC50=1.94 nM） is a potent angiotensin-converting enzyme (ACE) inhibitor.
T6486 Enalapril Maleate MK-421 Maleate,Renitec Maleate,Glioten Maleate,MK-421 (maleate),Vasotec Maleate RAAS
Enalapril Maleate (MK-421 Maleate), an angiotensin-converting enzyme (ACE) inhibitor, is utilized in the treatment of hypertension, chronic heart failure , and diabetic nephropathy.
T6698 Temocapril hydrochloride CS-622 HCl,Acecol,Temocapril HCl,CS-622 RAAS
Temocapril hydrochloride (CS-622 HCl), the hydrochloride of Temocapril, is a long-acting ACE inhibitor used for the therapy of hypertension.
T25226 Ceronapril Ceronaprilum,SQ 29852,SQ-29852,SQ29852 RAAS
Ceronapril (SQ 29852) is an orally active and potent angiotensin-converting enzyme (ACE) inhibitor (IC50 : 36 nM) for the study of dementia and hypertension.
T5329 Trandolapril Angiotensin-converting Enzyme (ACE)
Trandolapril is an orally administered angiotensin converting enzyme (ACE) inhibitor that is hydrolysed to the active diacid trandolaprilat.
T20689 Temocaprilat RNH-5139,RS-5139,RNH 5139,RNH5139,RS5139,RS 5139 Angiotensin-converting Enzyme (ACE)
Temocaprilat (RS5139) is an Angiotensin-converting Enzyme (ACE) inhibitor. Temocaprilat is effectively excreted in bile via cMOAT that is deficient in EHBR and that many of other ACE inhibitors have low affinity for cMOA...
T3281 Delapril hydrochloride indalapril,Alindapril Hydrochloride,Delapril Hydrochloride,CV 3317 RAAS
Delapril hydrochloride (indalapril) is a prodrug; it is converted into two active metabolites, 5-hydroxy delapril diacid and delapril diacid. These metabolites bind completely to and inhibit angiotensin-converting enzyme...
T27827 Libenzapril CGS 16617,Abutapril Angiotensin-converting Enzyme (ACE)
Libenzapril (CGS 16617) is a potent angiotensin-converting enzyme inhibitor used to study myocardial injury.
T0805 Quinapril hydrochloride CI-906,PD-109452-2,Quinapril HCl RAAS
Quinapril hydrochloride (PD-109452-2) is an angiotensin-converting enzyme (ACE) inhibitor used in the therapy of hypertension and congestive heart failure. Quinapril hydrochloride is associated with a low rate of transie...
T20758 Trandolaprilat RU44403,RU-44403,Trandolaprilate,Trandolaprilatum,RU 44403
Trandolaprilat is an inhibitor of non-sulfhydryl angiotensin-converting enzyme.
T6340L Enalaprilat MK422,MK 422,MK 421 diacid,Enalapril acid,MK-422
Enalaprilat, the active metabolite of Enalapril, is a effective intravenously administered angiotensin-converting enzyme inhibitor. It is an effective agent for the treatment of essential hypertension and has beneficial ...
T12704 Rentiapril SA-446 RAAS
Rentiapril is an orally active inhibitor of angiotensin converting enzyme (ACE), with antihypertensive activity.
T13274 Utibapril FPL 63547 Others
Utibapril is an inhibitor of angiotensin-converting enzyme (ACE) with antihypertensive activities.
T68412 Cilazaprilat
Cilazaprilat is the active metabolite of cilazapril, a pyridazine angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity.
T11642 Imidaprilate Imidaprilat,6366A RAAS
Imidaprilate is an active metabolite of TA-6366, acts as a potent angiotensin-converting enzyme (ACE) inhibitor (IC50: 2.6 nM). It is used in the research of the hypertensive disease.
T71065 Quinapril-d5
Quinapril-d5 is intended for use as an internal standard for the quantification of quinapril by GC- or LC-MS. Quinapril is a prodrug form of the angiotensin converting enzyme (ACE) inhibitor quinaprilat. In vivo, quinapr...
T13196 Trandolaprilate D5 Trandolaprilat D5,RU 44403 D5 Others
Trandolaprilate D5 is a deuterium-labeled Trandolaprilate. Trandolaprilate is an inhibitor of angiotensin-converting enzyme (ACE).
T62005 Imidapril
Imidapril (TA-6366 free base) is an orally active inhibitor of angiotensin-converting enzyme (ACE) and MMP-9. Imidapril inhibits the conversion of angiotensin I to angiotensin II, thereby reduces total peripheral resista...
T62992 Trandolapril hydrochloride
Trandolapril (RU44570) hydrochloride is a non-mercapto precursor compound that is hydrolysed to active diacetyl (Trandolapril hydrochlorideat). Trandolapril hydrochloride has been studied in hypertension and congestive h...
T68435 Cilazapril HCl
Cilazapril, also known as Ro 31 2848, is a potent ACE inhibitor used for hypertension. Cilazapril is a prodrug that is hydrolyzed after absorption to its main metabolite cilazaprilat. Cilazapril is a monoethyl ester, whi...
T11194 Enalaprilat D5 MK-422 D5 Others
Enalaprilat D5 is the deuterium labeled Enalaprilat, which is an angiotensin-converting enzyme (ACE) inhibitor.
T11193 Enalaprilat-d5 sodium MK-422 D5 Sodium Salt,Enalaprilat D5 Sodium Salt Others
Enalaprilat D5 Sodium Salt is the deuterium labeled Enalaprilat, which is an angiotensin-converting enzyme (ACE) inhibitor.
T72318 Trandolaprilate hydrate Trandolaprilat hydrate ; RU 44403 hydrate,RU 44403 hydrate,Trandolaprilat hydrate
Trandolaprilate hydrate, the main bioactive metabolite of Trandolapril and a potent angiotensin-converting enzyme (ACE) inhibitor, exhibits high lipophilicity and partially inhibits angiotensin-I-mediated c-fos induction...
T21049 Quinaprilat CI-928,CI928,CI 928
Quinaprilat inhibits angiotensin converting enzyme.
T11192 Enalapril D5 maleate MK-421 D5 maleate Others
Enalapril D5 maleate is deuterium labeled Enalapril, which is an angiotensin converting enzyme (ACE) inhibitor.
T6444 Cilazapril Monohydrate Ro 31-2848 monohydrate,Justor RAAS
Cilazapril Monohydrate (Justor) is an angiotensin-converting enzyme (ACE) inhibitor used for the treatment of hypertension and congestive heart failure.
T13195 Trandolapril D5 RU44570 D5 Others
Trandolapril D5 is a deuterium labeled Trandolapril. Trandolapril is an orally active inhibitor of angiotensin converting enzyme (ACE) for hypertension and congestive heart failure (CHF).
T1605L Enalapril sodium (-)-Enalapril sodium
Enalapril sodium is used to treat high blood pressure, diabetic kidney disease, and heart failure and can be generally used with a diuretic such as furosemide for heart failure.
T24820 Spiraprilat Spiraprilate,SCH-33861,SCH 33861,SCH33861
Spiraprilat is an ACE inhibitor. It also is an active metabolite of spirapril.
T20167 Cilazapril Ro-34-2848,Ro 34-2848,Cilazapril (anhydrous),Ro34-2848
Cilazapril is an angiotensin-converting enzyme inhibitor. It has been researched for mild to moderate essential hypertension.
T28485 Quinaprilat hydrate Quinaprilat,CI-928,CI 928,BRN 5653070
Quinaprilat is the active metabolite of quinapril, an angiotensin-converting enzyme inhibitor used in the treatment of congestive heart failure and hypertension.
T63425 Spirapril hydrochloride
Spirapril (SCH 33844) hydrochloride is a potent inhibitor of angiotensin-converting enzyme (ACE) and is an orally active prodrug of spiripril. Spirapril hydrochloride can be used to study hypertension and congestive hear...
T27608 Indolapril hydrochloride REV 6000A(SS),CI-907,CI 907,CI907,Indolapril HCl
Indolapril hydrochloride is a nonsulfhydryl angiotensin converting enzyme (ACE) inhibitor with antihypertensive activity.
T34696 Spirapril HCl BRN4277924,BRN-4277924,BRN 4277924,Spiraprilum,Spirapril,Espirapril
Spiropril is an ACE inhibitor antihypertensive drug, which belongs to the bicarboxyl group of ACE inhibitors and is used in the treatment of hypertension.
T3281L Delapril Alindapril
Delapril is an ACE inhibitor. It blocks the conversion of angiotensin I to angiotensin II.
T68085 Idrapril
Idrapril,an angiotensin-converting enzyme (ACE) inhibitor acts by binding the catalytically important zinc ion to a hydroxamic group.
T77364 Sibeprenlimab VIS649,VIS-649 Others
Sibeprenlimab (VIS649) is a humanized IgG 2 monoclonal antibody that suppresses APRIL. Sibeprenlimab has an inhibitory effect on APRIL and may be studied for the prevention and treatment of kidney disease (IgAN).
T80730 Zigakibart BION-1301
Zigakibart (BION-1301) is a humanized monoclonal antibody of the IgG4-kappa subtype, targeting TNFSF13 (tumor necrosis factor (TNF) superfamily member 13, APRIL, CD256), and exhibits anti-inflammatory activity [1].
T27563 Hydroxypropyl-beta-cyclodextrin HP-beta-CyD,VTS-270,HP-beta-CD,Hydroxypropyl-beta-cyclodextri,THPB,HPbCD
Hydroxypropyl-beta-cyclodextrin, also known as Hydroxypropyl-beta-cyclodextrin; THPB; HP-beta-CD; HPbCD; HP-beta-CyD; VTS-270; HPbetaCD; HPbetaCyD, is a drug candidate potentially for the treatment of Niemann-Pick type C...
T78309 Telitacicept RC18
Telitacicept (RC18), a fully human TACI-Fc fusion protein, acts as a dual inhibitor of B lymphocyte stimulator (BLyS) and APRIL (a proliferation-inducing ligand), effectively impeding B lymphocyte proliferation. This com...
T76849 Bamlanivimab
Bamlanivimab, an Anti-Human SARS-CoV-2 monoclonal antibody (mAb), was the first of its kind to receive Emergency Use Authorization (EUA) from the U.S. Food and Drug Administration (FDA) in November 2020 for COVID-19 trea...
T37130 MRTX1133 formic
MRTX1133 is a highly selective, first-in-class inhibitor of KRAS G12D. MRTX1133 targets the KRAS G12D protein in both active and inactive states. MRTX1133 selectively inhibits KRAS G12D mutant, but not KRAS wild-type, tu...
T36630 MRTX9768 hydrochloride
MRTX9768 hydrochloride is a potent, orally active PRMT5 inhibitor. MRTX9768 hydrochloride is a synthetic lethal-based inhibitor binding the PRMT5-MTA complex[1]. MRTX9768 inhibits SDMA and cell proliferation in HCT116 MT...

Compounds

Rentiapril racemate
T16731
Synonym: (Rac)-SA-446,SA-446 racemate,(Rac)-Rentiapril
Target: Angiotensin-converting Enzyme (ACE)
Enalapril IMpurity B
T1689
Synonym: (+)-N-[1-(S)-Ethoxycarbonxyl-3-phenylpropyl]-L-alanine
Target: Others
Imidapril hydrochloride
T6542
Synonym: Novaloc,Imidapril HCl,Tanapril,TA-6366
Target: RAAS
Enalapril
T1605
Synonym: MK-421
Target: RAAS, MRP
Enalaprilat Dihydrate
T6340
Synonym: MK-422,MK-422 Dihydrate
Target: RAAS, Autophagy
Enalapril Maleate
T6486
Synonym: MK-421 Maleate,Renitec Maleate,Glioten Maleate,MK-421 (maleate),Vasotec Maleate
Target: RAAS
Temocapril hydrochloride
T6698
Synonym: CS-622 HCl,Acecol,Temocapril HCl,CS-622
Target: RAAS
Ceronapril
T25226
Synonym: Ceronaprilum,SQ 29852,SQ-29852,SQ29852
Target: RAAS
Trandolapril
T5329
Synonym:
Target: Angiotensin-converting Enzyme (ACE)
Temocaprilat
T20689
Synonym: RNH-5139,RS-5139,RNH 5139,RNH5139,RS5139,RS 5139
Target: Angiotensin-converting Enzyme (ACE)
Delapril hydrochloride
T3281
Synonym: indalapril,Alindapril Hydrochloride,Delapril Hydrochloride,CV 3317
Target: RAAS
Libenzapril
T27827
Synonym: CGS 16617,Abutapril
Target: Angiotensin-converting Enzyme (ACE)
Quinapril hydrochloride
T0805
Synonym: CI-906,PD-109452-2,Quinapril HCl
Target: RAAS
Trandolaprilat
T20758
Synonym: RU44403,RU-44403,Trandolaprilate,Trandolaprilatum,RU 44403
Target:
Enalaprilat
T6340L
Synonym: MK422,MK 422,MK 421 diacid,Enalapril acid,MK-422
Target:
Rentiapril
T12704
Synonym: SA-446
Target: RAAS
Utibapril
T13274
Synonym: FPL 63547
Target: Others
Cilazaprilat
T68412
Synonym:
Target:
Imidaprilate
T11642
Synonym: Imidaprilat,6366A
Target: RAAS
Quinapril-d5
T71065
Synonym:
Target:
Trandolaprilate D5
T13196
Synonym: Trandolaprilat D5,RU 44403 D5
Target: Others
Imidapril
T62005
Synonym:
Target:
Trandolapril hydrochloride
T62992
Synonym:
Target:
Cilazapril HCl
T68435
Synonym:
Target:
Enalaprilat D5
T11194
Synonym: MK-422 D5
Target: Others
Enalaprilat-d5 sodium
T11193
Synonym: MK-422 D5 Sodium Salt,Enalaprilat D5 Sodium Salt
Target: Others
Trandolaprilate hydrate
T72318
Synonym: Trandolaprilat hydrate ; RU 44403 hydrate,RU 44403 hydrate,Trandolaprilat hydrate
Target:
Quinaprilat
T21049
Synonym: CI-928,CI928,CI 928
Target:
Enalapril D5 maleate
T11192
Synonym: MK-421 D5 maleate
Target: Others
Cilazapril Monohydrate
T6444
Synonym: Ro 31-2848 monohydrate,Justor
Target: RAAS
Trandolapril D5
T13195
Synonym: RU44570 D5
Target: Others
Enalapril sodium
T1605L
Synonym: (-)-Enalapril sodium
Target:
Spiraprilat
T24820
Synonym: Spiraprilate,SCH-33861,SCH 33861,SCH33861
Target:
Cilazapril
T20167
Synonym: Ro-34-2848,Ro 34-2848,Cilazapril (anhydrous),Ro34-2848
Target:
Quinaprilat hydrate
T28485
Synonym: Quinaprilat,CI-928,CI 928,BRN 5653070
Target:
Spirapril hydrochloride
T63425
Synonym:
Target:
Indolapril hydrochloride
T27608
Synonym: REV 6000A(SS),CI-907,CI 907,CI907,Indolapril HCl
Target:
Spirapril HCl
T34696
Synonym: BRN4277924,BRN-4277924,BRN 4277924,Spiraprilum,Spirapril,Espirapril
Target:
Delapril
T3281L
Synonym: Alindapril
Target:
Idrapril
T68085
Synonym:
Target:
Sibeprenlimab
T77364
Synonym: VIS649,VIS-649
Target: Others
Zigakibart
T80730
Synonym: BION-1301
Target:
Hydroxypropyl-beta-cyclodextrin
T27563
Synonym: HP-beta-CyD,VTS-270,HP-beta-CD,Hydroxypropyl-beta-cyclodextri,THPB,HPbCD
Target:
Telitacicept
T78309
Synonym: RC18
Target:
Bamlanivimab
T76849
Synonym:
Target:
MRTX1133 formic
T37130
Synonym:
Target:
MRTX9768 hydrochloride
T36630
Synonym:
Target:
Cat No. Product Name Synonyms Targets
T5266 Tricaprilin Glycerol Tri-n-octanoate,trioctanoin,tricaprylic glyceride,Glyceryl trioctanoate Others , Endogenous Metabolite
Tricaprilin (Glycerol Tri-n-octanoate) is used in study for patients with mild to moderate Alzheimer's disease. Tricaprilin also has a role as an anticonvulsant and a plant metabolite.

Natural Products

Tricaprilin
T5266
Synonym: Glycerol Tri-n-octanoate,trioctanoin,tricaprylic glyceride,Glyceryl trioctanoate
Target: Others, Endogenous Metabolite

Recombinant Proteins

Species：
Human (6)
Cynomolgus (2)
Mouse (2)
Rhesus (1)
Expression System：
HEK293 Cells (11)
Tag：
N-His-Flag (3)
N-His-Avi, N-Flag (2)
N-hFc (2)
C-His (1)
C-His-Avi (1)
N-6xHis-Flag (1)
N-Flag-His (1)
Cat No. Product Name Species Expression System
TMPJ-00137 APRIL/TNFSF13 Protein, Human, Recombinant (Flag & His) Human HEK293 Cells
APRIL (a proliferation-inducing ligand), also known as TNFSF13, TALL2, TRDL1, and CD256, is a member of the TNF ligand superfamily. It is synthesized as a 32 kDa proprotein which is cleaved by furin in the Golgi to relea...
TMPK-00140 APRIL/TNFSF13 Trimer Protein, Human, Recombinant (His & Avi & Flag), Biotinylated Human HEK293 Cells
The APRIL (a proliferation-inducing ligand), also known as TNFSF13, TALL2, TRDL1, and CD256, is a member of the TNF ligand superfamily.Both APRIL and its close relative BAFF bind and signal through the TNF superfamily re...
TMPK-01163 APRIL/TNFSF13 Protein, Mouse, Recombinant (His & Flag) Mouse HEK293 Cells
The APRIL (a proliferation-inducing ligand), also known as TNFSF13, TALL2, TRDL1, and CD256, is a member of the TNF ligand superfamily.Both APRIL and its close relative BAFF bind and signal through the TNF superfamily re...
TMPK-00141 APRIL/TNFSF13 Trimer Protein, Human, Recombinant (His & Flag) Human HEK293 Cells
The APRIL (a proliferation-inducing ligand), also known as TNFSF13, TALL2, TRDL1, and CD256, is a member of the TNF ligand superfamily.Both APRIL and its close relative BAFF bind and signal through the TNF superfamily re...
TMPK-01349 APRIL/TNFSF13 Trimer Protein, Cynomolgus, Recombinant (His & Avi, Flag) Cynomolgus HEK293 Cells
The APRIL (a proliferation-inducing ligand), also known as TNFSF13, TALL2, TRDL1, and CD256, is a member of the TNF ligand superfamily.Both APRIL and its close relative BAFF bind and signal through the TNF superfamily re...
TMPK-00142 APRIL/TNFSF13 Trimer Protein (Primary Amine Labeling), Human, Recombinant (His & Flag), Biotinylated Human HEK293 Cells
The APRIL (a proliferation-inducing ligand), also known as TNFSF13, TALL2, TRDL1, and CD256, is a member of the TNF ligand superfamily.Both APRIL and its close relative BAFF bind and signal through the TNF superfamily re...
TMPJ-00456 APRIL/TNFSF13 Protein, Mouse, Recombinant (hFc) Mouse HEK293 Cells
Tumor necrosis factor ligand superfamily member 13 belongs to the tumor necrosis factor family. It is also known as APRIL, TALL2, TRDL1, and CD256. It is synthesized as a 32 kDa proprotein which is cleaved by furin in th...
TMPK-00070 BAFFR/TNFRSF13C Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293 Cells
BAFF binds to three TNF receptor superfamily members: B-cell maturation antigen (BCMA/TNFRSF17), transmembrane activator and calcium-modulator and cyclophilin ligand interactor (TACI/TNFRSF13B) and BAFF receptor (BAFF R/...
TMPK-01254 BAFFR/TNFRSF13C Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293 Cells
BAFF binds to three TNF receptor superfamily members: B-cell maturation antigen (BCMA / TNFRSF17), transmembrane activator and calcium-modulator and cyclophilin ligand interactor (TACI/TNFRSF13B) and BAFF receptor (BAFF ...
TMPJ-00066 BCMA/TNFRSF17 Protein, Human, Recombinant (His & Flag) Human HEK293 Cells
B cell maturation antigen (BCMA) is a member of the TNF receptor superfamily. It has been designated TNFRSF17. Mouse BCMA is a 185 amino acid (aa) protein consisting of a 49 aa extracellular domain, a 23 aa transmembrane...
TMPJ-00623 BAFF/TNFSF13B Protein, Rhesus macaque, Recombinant (hFc) Rhesus HEK293 Cells
TNFSF13B is also known as B-cell activating factor (BAFF), BLyS and TNLG7A, is a member of TNF ligand superfamily. TNFSF/TNFRSF members function as key molecules in local and systemic inflammatory network, and the plasma...
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