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Indolapril hydrochloride

Catalog No. T27608 CAS 80828-32-6

Synonyms: REV 6000A(SS), CI-907, CI 907, CI907, Indolapril HCl

Indolapril hydrochloride is a nonsulfhydryl angiotensin converting enzyme (ACE) inhibitor with antihypertensive activity.

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Indolapril hydrochloride Chemical Structure

Indolapril hydrochloride, CAS 80828-32-6

Pack Size	Availability	Price/USD
25 mg	6-8 weeks	$ 1,520.00
50 mg	6-8 weeks	$ 1,980.00
100 mg	6-8 weeks	$ 2,500.00

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This compound is a customized synthesis product. We have a strong synthesis team with excellent synthesis technology and capabilities. However, due to various objective factors, there is a low probability that the synthesis will not be successful. If you need to learn more, please feel free to consult us, we will serve you wholeheartedly.

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Indolapril hydrochloride is a nonsulfhydryl angiotensin converting enzyme (ACE) inhibitor with antihypertensive activity.

Synonyms	REV 6000A(SS), CI-907, CI 907, CI907, Indolapril HCl
Molecular Weight	467
Formula	C24H35ClN2O5
CAS No.	80828-32-6

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Blankley CJ, Kaltenbronn JS, DeJohn DE, Werner A, Bennett LR, Bobowski G, Krolls U, Johnson DR, Pearlman WM, Hoefle ML, et al. Synthesis and structure-activity relationships of potent new angiotensin converting enzyme inhibitors containing saturated bicyclic amino acids. J Med Chem. 1987 Jun;30(6):992-8. PubMed PMID: 3035180. 2. La Rocca PT, Squibb RE, Powell ML, Szot RJ, Black HE, Schwartz E. Acute and subchronic toxicity of a nonsulfhydryl angiotensin-converting enzyme inhibitor. Toxicol Appl Pharmacol. 1986 Jan;82(1):104-11. PubMed PMID: 3003964. 3. Roark WH, Tinney FJ, Cohen D, Essenburg AD, Kaplan HR. Synthesis and biological activity of modified peptide inhibitors of angiotensin-converting enzyme. J Med Chem. 1985 Sep;28(9):1291-5. PubMed PMID: 2993618. 4. Brunner HR, Nussberger J, Waeber B. The present molecules of converting enzyme inhibitors. J Cardiovasc Pharmacol. 1985;7 Suppl 1:S2-11. Review. PubMed PMID: 2580170.

Dose Conversion

You can also refer to dose conversion for different animals. More

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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An example of a molarity calculation using the molarity calculator
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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The answer of 19.713 mg appears in the Mass box

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The dilution calculator is a useful tool which allows you to calculate how to dilute a stock solution of known concentration. Enter C1, C2 & V2 to calculate V1.

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An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
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The answer of 100 microliter (0.1 ml) appears in the Volume (start) box

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Indolapril hydrochloride 80828-32-6 REV 6000A(SS) CI-907 CI 907 CI907 Indolapril HCl Indolapril Hydrochloride inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.