Home Tools
Log in
Cart

β-Elemonic Acid

Catalog No. T2S0618   CAS 28282-25-9
Synonyms: 3-oxo Tirucallic Acid, Beta-Elemonic acid, 3-Oxotirucallenoic Acid, Elemadienonic Acid

β-Elemonic Acid (3-Oxotirucallenoic Acid) exhibits anti-inflammatory effects. Beta-Elemonic acid inhibits proliferation by inducing hypoploid cells and cell apoptosis, the anticancer effects of beta-Elemonic acid are related to the MAPK signaling pathway, ROS activation and glutathione depletion in human A549 lung cancer cells. Beta-Elemonic acid exhibits prolyl endopeptidase inhibitory activities.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
β-Elemonic Acid Chemical Structure
β-Elemonic Acid, CAS 28282-25-9
Pack Size Availability Price/USD Quantity
1 mg In stock $ 44.00
5 mg In stock $ 96.00
10 mg In stock $ 165.00
25 mg In stock $ 275.00
50 mg In stock $ 398.00
100 mg In stock $ 592.00
500 mg In stock $ 1,280.00
1 mL * 10 mM (in DMSO) In stock $ 118.00
Bulk Inquiry
Get quote
Select Batch  
Purity: 99.8%
Purity: 99.48%
Contact us for more batch information
Biological Description
Chemical Properties
Storage & Solubility Information
Description β-Elemonic Acid (3-Oxotirucallenoic Acid) exhibits anti-inflammatory effects. Beta-Elemonic acid inhibits proliferation by inducing hypoploid cells and cell apoptosis, the anticancer effects of beta-Elemonic acid are related to the MAPK signaling pathway, ROS activation and glutathione depletion in human A549 lung cancer cells. Beta-Elemonic acid exhibits prolyl endopeptidase inhibitory activities.
Synonyms 3-oxo Tirucallic Acid, Beta-Elemonic acid, 3-Oxotirucallenoic Acid, Elemadienonic Acid
Molecular Weight 454.68
Formula C30H46O3
CAS No. 28282-25-9

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 32 mg/mL(70.4 mM)

Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.: Soluble

TargetMolReferences and Literature

1. Wu T T , Lu C L , Lin H I , et al. β-Elemonic acid inhibits the cell proliferation of human lung adenocarcinoma A549 cells: The role of MAPK, ROS activation and glutathione depletion[J]. Oncology Reports, 2016, 35(1):227-234.

Related compound libraries

This product is contained In the following compound libraries:
Anti-Cancer Active Compound Library Microbial Natural Product Library Anti-Cardiovascular Disease Compound Library Anti-Ovarian Cancer Compound Library NF-κB Signaling Compound Library Human Metabolite Library Neuronal Signaling Compound Library Anti-Tumor Natural Product Library Pyroptosis Compound Library Autophagy Compound Library

Related Products

Related compounds with same targets
Ac-Pro-Gly-Pro-OH Vandetanib Dehydrotrametenolic acid Ulocuplumab Tomentosin Ro 90-7501 Lexatumumab Calycosin

TargetMolDose Conversion

You can also refer to dose conversion for different animals. More

TargetMol In vivo Formulation Calculator (Clear solution)

Step One: Enter information below
Dosage
mg/kg
Average weight of animals
g
Dosing volume per animal
ul
Number of animals
Step Two: Enter the in vivo formulation
% DMSO
%
% Tween 80
% ddH2O
Calculate Reset

TargetMolCalculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculation
Molecular Weight Calculator
=
X
X

Molarity Calculator allows you to calculate the

  • Mass of a compound required to prepare a solution of known volume and concentration
  • Volume of solution required to dissolve a compound of known mass to a desired concentration
  • Concentration of a solution resulting from a known mass of compound in a specific volume
See Example

An example of a molarity calculation using the molarity calculator
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
Enter 197.13 into the Molecular Weight (MW) box
Enter 10 into the Concentration box and select the correct unit (millimolar)
Enter 10 into the Volume box and select the correct unit (milliliter)
Press calculate
The answer of 19.713 mg appears in the Mass box

X
=
X

Calculator the dilution required to prepare a stock solution

Calculate the dilution required to prepare a stock solution
The dilution calculator is a useful tool which allows you to calculate how to dilute a stock solution of known concentration. Enter C1, C2 & V2 to calculate V1.

See Example

An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
Enter 10 into the Concentration (start) box and select the correct unit (millimolar)
Enter 50 into the Concentration (final) box and select the correct unit (micromolar)
Enter 20 into the Volume (final) box and select the correct unit (milliliter)
Press calculate
The answer of 100 microliter (0.1 ml) appears in the Volume (start) box

=
/

Calculate the volume of solvent required to reconstitute your vial.

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial.
Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

g/mol

Enter the chemical formula of a compound to calculate its molar mass and elemental composition

Tip: Chemical formula is case sensitive: C10H16N2O2 c10h16n2o2

Instructions to calculate molar mass (molecular weight) of a chemical compound:
To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.
Definitions of molecular mass, molecular weight, molar mass and molar weight:
Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed n the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

bottom

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

β-Elemonic Acid 28282-25-9 Apoptosis Immunology/Inflammation Metabolism Neuroscience NF-Κb Reactive Oxygen Species COX lung Prolyl Endopeptidase (PREP) Boswellia b-Elemonic Acid Cyclooxygenase Triterpene Endogenous Metabolite A549 POP 3-oxo Tirucallic Acid Anticancer β-Elemonic acid β Elemonic Acid Inhibitor prolyl oligopeptidase anti-inflammatory Beta-Elemonic acid βElemonic Acid papyrifera cancer 3-Oxotirucallenoic Acid inhibit human Elemadienonic Acid inhibitor

 

TargetMol