20
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T39392L | C-Type Natriuretic Peptide (CNP) (1-22), human acetate | C-Type Natriuretic Peptide (CNP) (1-22), human acetate(1966153-17-2 Free base) | Others |
C-Type Natriuretic Peptide (CNP) (1-22), human acetate is an agonist of natriuretic peptide receptor B (NPR-B), an endothelial-derived relaxant and growth inhibitory factor. C-Type Natriuretic Peptide (CNP) (1-22), huma... | |||
T13867 | RH01386 | Others | |
RH01386 is a small molecule that can prevent ER stress-induced β cell dysfunction and death, and inhibits proapoptotic gene expression,has the potential for type 2 diabetes treatment. RH01386 restores ER stress-impaired ... | |||
T7544 | Fucoidan | Others | |
Fucoidan is found in various species of brown seaweed and algae,with anticancer, antiviral, neuroprotective, immune-modulating. | |||
T2210 | Genipin | (+)-Genipin | Others , Autophagy |
Genipin ((+)-Genipin), an active aglycone derived from an iridoid glycoside called geniposide, is found in the fruit of Gardenia jasminoides Ellis. | |||
T9022 | AZD9977 | AZD 9977 | Glucocorticoid Receptor |
AZD9977 is a novel, selective modulator of mineralocorticoid receptor . | |||
T15432 | GSK256073 | GPR , Others | |
GSK256073 is an orally active GPR109A agonist. GSK256073 also is a long-lasting and non-flushing HCA2 (hydroxy-carboxylic acid receptor 2) full agonist (pEC50: 7.5). GSK256073 acutely improves glucose homeostasis via inh... | |||
T15159 | Dorzagliatin | HMS5552 | Glucokinase |
Dorzagliatin (HMS5552) is a dual-acting glucokinase (GK) activator. It also improves glycaemic control and pancreatic β-cell function in type 2 diabetes. | |||
T14315 | AR-9281 | APAU | Epoxide Hydrolase |
AR-9281 (APAU) is a potent and selective inhibitor of soluble epoxide hydrolase (s-EH) potentially for the treatment of hypertension and type 2 diabetes | |||
T3978 | Linerixibat | GSK2330672,Iinerixibat | HBV |
Linerixibat (GSK2330672) is a highly effective, nonabsorbable ASBT inhibitor (IC50: 42 ± 3 nM). It can lower glucose in an animal model of type 2 diabetes and shows excellent developability properties. | |||
T8944 | TTA-A2 | Calcium Channel | |
TTA-A2 is a selective T-type calcium channel antagonist as a potent anticonvulsant that the Cav3.1 isoform plays a prominent role in mediating. TTA-A2 is equally potent against the Cav3.1 (a1G) and Cav3.2 (a1H) channels ... | |||
TN1418 | Azaleatin | DPP-4 | |
Azaleatin is a natural product from Rhododendron simsii. Azaleatin is a dipeptidyl peptidase-IV inhibitor. Azaleatin can be used for type-2 diabetes and obesity studies. | |||
T63893 | Adenylyl cyclase type 2 agonist-1 | ||
Adenylyl cyclase type 2 agonist-1 is a potent agonist of adenylyl cyclase type 2 (AC2) (EC50: 90 nM). It is a potential lead compound in the fight against respiratory diseases. | |||
T64203 | T-Type calcium channel inhibitor 2 | ||
T-Type calcium channel inhibitor 2 (compound 6g) is a potent inhibitor of the T-type calcium channel, acting on Cav3.1 (α1G) (IC50: 31.0 μM), Cav3.2 (α1H) (IC50: 83.1 μM), Cav3.3 (α1I) (α1H) ( T-Type calcium channel inhi... | |||
T16074 | Mifobate | SR-202 | PPAR |
Mifobate (SR-202) is a potent and specific antagonist of PPARγ. Mifobate shows antiobesity, antidiabetic and antiatherosclerotic effects[1]. | |||
T1088 | Repaglinide | AG-EE 388 ZW,AG-EE 623ZW | Potassium Channel , PPAR |
Repaglinide (AG-EE 623ZW) is a benzoic acid derivative that stimulates insulin secretion from the pancreas and is used in the therapy of type 2 diabetes. Repaglinide has been linked to rare instances of clinically appare... | |||
T21900 | ML-336 | Others | |
ML-336 is an inhibitor of of the Venezuelan equine encephalitis virus (VEEV) strain TC-83. | |||
T0314 | Hexylresorcinol | 4-Hexylresorcinol | Apoptosis , Tyrosinase , Antibacterial , Parasite |
Hexylresorcinol (4-Hexylresorcinol) is a substituted dihydroxybenzene used topically as an antiseptic for the treatment of minor skin infections. | |||
T12302 | OMDM-1 | (Z)-N-[(2S)-1-hydroxy-3-(4-hydroxyphenyl)propan-2-yl]octadec-9-enamide | Endogenous Metabolite |
OMDM-1 ((Z)-N-[(2S)-1-hydroxy-3-(4-hydroxyphenyl)propan-2-yl]octadec-9-enamide) is a selective and metabolically stable anandamide cellular uptake (ACU)inhibitor with a Ki of 2.4 μM. | |||
T7132 | (Rac)-Brassinazole | BRASSINAZOLE | P450 |
(Rac)-Brassinazole are a class of phytohormones with essential roles in plant growth and development, including the promotion of stem elongation and cell division. Brassinazole is a triazole-type brassinosteroid biosynth... | |||
T1603 | Glipizide | CP 28720,K 4024 | Potassium Channel , PPAR , ABC |
Glipizide (CP 28720) is a short-acting, second-generation sulfonylurea with hypoglycemic activity. |