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AR-9281

Catalog No. T14315 CAS 913548-29-5

Synonyms: APAU

AR9281 is a potent and selective inhibitor of soluble epoxide hydrolase (s-EH) potentially for the treatment of hypertension and type 2 diabetes

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AR-9281, CAS 913548-29-5

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

AR9281 is a potent and selective inhibitor of soluble epoxide hydrolase (s-EH) potentially for the treatment of hypertension and type 2 diabetes

Synonyms	APAU
Molecular Weight	319.44
Formula	C18H29N3O2
CAS No.	913548-29-5

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

DMSO: 25 mg/mL (78.26 mM), Need ultrasonic

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Chen D, et al. Pharmacokinetics and pharmacodynamics of AR9281, an inhibitor of soluble epoxide hydrolase, in single- and multiple-dose studies in healthy human subjects. J Clin Pharmacol. 2012 Mar;52(3):319-28.

Related compound libraries

This product is contained In the following compound libraries：

Inhibitor Library Anti-Metabolism Disease Compound Library Anti-Aging Compound Library Bioactive Compound Library Anti-Diabetic Compound Library

Related Products

Related compounds with same targets

beta-Amyrin acetate (Rac)-EC5026 1-Cyclohexyl-3-dodecyl urea AUDA TPPU Dual FAAH/sEH-IN-1 ARM1 BI-1935

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

AR-9281 913548-29-5 代谢 Epoxide Hydrolase inflammation APAU AR9281 hypertension MsEH HsEH soluble epoxide hydrolase (s-EH) oral inhibit Inhibitor AR 9281 type 2 diabetes inhibitor

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