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AR-9281

Name: AR-9281
Brand: TargetMol
SKU: T14315
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T14315Cas No. 913548-29-5

Alias APAU

AR-9281 (APAU) is a potent and selective inhibitor of soluble epoxide hydrolase (s-EH) potentially for the treatment of hypertension and type 2 diabetes

AR-9281

🥰Excellent

Purity: 99.79%

Catalog No. T14315Alias APAUCas No. 913548-29-5

AR-9281 (APAU) is a potent and selective inhibitor of soluble epoxide hydrolase (s-EH) potentially for the treatment of hypertension and type 2 diabetes

Pack Size	Price	Availability
2 mg	$29	In Stock
5 mg	$48	In Stock
10 mg	$77	In Stock
25 mg	$158	In Stock
50 mg	$251	In Stock
100 mg	$397	In Stock
200 mg	$578	In Stock
1 mL x 10 mM (in DMSO)	$53	In Stock

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Batch Information

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Purity:99.79%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	AR-9281 (APAU) is a potent and selective inhibitor of soluble epoxide hydrolase (s-EH) potentially for the treatment of hypertension and type 2 diabetes
Synonyms	APAU

Chemical Properties

Molecular Weight	319.44
Formula	C₁₈H₂₉N₃O₂
Cas No.	913548-29-5
Smiles	CC(=O)N1CCC(CC1)NC(=O)NC12CC3CC(CC(C3)C1)C2
Relative Density.	1.19 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 25 mg/mL (78.26 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.1305 mL	15.6524 mL	31.3048 mL	156.5239 mL
5 mM	0.6261 mL	3.1305 mL	6.2610 mL	31.3048 mL
10 mM	0.3130 mL	1.5652 mL	3.1305 mL	15.6524 mL
20 mM	0.1565 mL	0.7826 mL	1.5652 mL	7.8262 mL
50 mM	0.0626 mL	0.3130 mL	0.6261 mL	3.1305 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc