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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TP1844L | Small Cardioactive Peptide B SCPB acetate | Small Cardioactive Peptide B SCPB acetate(84746-43-0 free base) | Others |
Small Cardioactive Peptide B SCPB acetate (Small Cardioactive Peptide B SCPB acetate (84746-43-0 free base)) is a neurally active peptide, stimulates adenylate cyclase activity in particulate fractions of both heart and ... | |||
TP1844 | Small Cardioactive Peptide B (SCPB) | Small Cardioactive Peptide B SCPB | |
Small Cardioactive Peptide B (SCPB), a neurally active peptide, stimulates adenylate cyclase activity in particulate fractions of both heart and gill tissues with EC50s of 0.1 and 1.0 μM, respectively. | |||
TP2407 | Small cardioactive peptide A | SCPA | |
Small cardioactive peptide A, as a neuropeptide that modulates neuromuscular synapsis in Aplysia, can also function as a neural cotransmitter in molluscs and exert a role in both the central and peripheral modulation of ... | |||
T33546 | Mytilus scp | Mytilus small cardioactive peptide | |
Mytilus scp isolated from Mytilus edulis is homologous to small cardioactive peptides from Aplysia. | |||
T22223 | 3PO | Glucokinase , Autophagy | |
3PO is a small-molecule inhibitor of PFKFB3 (IC50: 22.9 μM), inhibiting the proliferation of several human malignant hematopoietic and adenocarcinoma cell lines (IC50: 1.4-24 μM). It suppresses glucose uptake, and decrea... | |||
T4903 | Heptadecanoic acid | Others , Endogenous Metabolite | |
Heptadecanoic acid is a fatty acid of exogenous (primarily ruminant) origin. Many "odd" length long chain amino acids are derived from the consumption of dairy fats (milk and meat). Heptadecanoic acid constitutes 0.61% o... | |||
T14557 | BI-1935 | Epoxide Hydrolase | |
BI-1935 is an inhibitor of soluble epoxide hydrolase (sEH). For diseases related to cardiovascular disease. | |||
T9929 | Ramucirumab | VEGFR | |
Ramucirumab is a human VEGFR-2 antagonist for the treatment of solid tumors. | |||
T8574 | SPHINX | Others | |
SPHINX is a new generation inhibitor of SPRK1 | |||
T10777 | CG347B | HDAC | |
CG347B is a selective inhibitor of HDAC6. | |||
T7156 | NIBR189 | EBI2/GPR183 | |
NIBR189 is a potent and selective antagonist of EBI2 (GPR183) receptor (IC50 of 11 and 15 nM for human and mouse EBI2 receptors, respectively) | |||
T12317 | Orelabrutinib | ICP-022 | BTK |
Orelabrutinib (ICP-022) is an orally active and irreversible inhibitor of Bruton's tyrosine kinase (BTK). | |||
T6031 | GNE0877 | GNE 0877,GNE-0877 | LRRK2 |
GNE0877 (GNE 0877) is a highly effective and specific leucine-rich repeat kinase 2 (LRRK2) inhibitor (Ki: 0.7 nM). | |||
T39275 | Befotertinib | D-0316,Befotertinib | EGFR |
Befotertinib (D-0316) is an inhibitor of EGFR tyrosine kinase and can be used for studies about EGFR T790M-positive non-small cell lung cancer. | |||
T21588 | Olomoucine | ERK , CDK | |
Olomoucine is an ATP competitive inhibitor of Cdk2/cyclin A, Cdc2/CyclinB, CDK2/CyclinE, CDK5/p35, and ERK1/p44 MAP kinase with IC50s of 7, 7, 7, 3 and 25 µM, respectively. Olomoucine regulates cell cycle and exhibits an... | |||
T13044 | Mevociclib | SY-1365 | CDK |
Mevociclib (SY-1365) is a highly selective covalent inhibitor of CDK7. SY-1365 possesses therapeutic potential in both hematological and solid tumors. | |||
T9865 | Almonertinib mesylate | EGFR | |
Almonertinib mesylate is an irreversible inhibitor of EGFR tyrosine kinase with high selectivity for EGFR-sensitizing and T790M resistance mutations. Almonertinib mesylate can be used in the non-small cell lung cancer st... | |||
T8756 | KRAS inhibitor-9 | DUN09716 | Apoptosis , Ras |
KRAS inhibitor-9 (DUN09716) is a potent KRAS inhibitor with Kd of 92 μM that blocks the formation of GTP-KRAS and downstream activation of KRAS. KRAS inhibitor-9 causes G2/M cell cycle arrest and induces apoptosis. KRAS ... | |||
T9522 | Rimtuzalcap | CAD-1883 | Potassium Channel |
Rimtuzalcap (CAD-1883) (CAD-1883), a pioneering selective positive allosteric modulator of small-conductance calcium-activated potassium channels (SK channels), is employed in the study of movement disorders such as spin... | |||
T60076 | Oritinib | SH-1028 | EGFR |
Oritinib (SH-1028) is an inhibitor of EGFR with IC50s of 18, 0.7, 4, 0.1, 1.4 and 0.89 nM for EGFR (wt), EGFR (L858R), EGFR (L861Q), EGFR (L858R/T790M), EGFR (d746-750), EGFR (d746-750/T790M), respectively. Oritinib can ... |