sensitizer — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
TN2080	Pinoresinol	(+)-Pinoresinol	Apoptosis , NF-κB , CDK , p53
	Pinoresinol ((+)-Pinoresinol) has antiinflammatory, hepatoprotective, and fungicidal activities, it can protect pial microcirculation from I-reperfusion injury, to increase nitric oxide release and to reduce oxidative st...		Apoptosis , NF-κB , CDK , p53
T21899	Misonidazole	SR-1354,SR1354,Ro 7-0582	GPX
	Misonidazole as a novel GPX inhibitors to cause oxidative stress in chemotherapy-resistant tumors.		GPX
T2607	MSDC 0160	CAY10415,Mitoglitazone,MSDC0160,MSDC-0160	Others , IGF-1R , Mitochondrial Metabolism
	MSDC 0160 (CAY10415) is a prototype mTOT-modulating insulin sensitizer being used in trials studying the treatment of Type 2 Diabetes and Alzheimer's Disease.		Others , IGF-1R , Mitochondrial Metabolism
T2046	Nimorazole	Nimorazol,Nitrimidazine,K-1900,Naxogin	Others , Antibiotic , Parasite
	Nimorazole (Nimorazol) is a nitroimidazole anti-infective.		Others , Antibiotic , Parasite
T5002	Methyl Aminolevulinate Hydrochloride	5-Aminolevulinic acid methyl ester,Methyl δ-aminolevulinate hydrochloride,Methyl 5-aminolevulinate Hydrochloride,Aminolevulinic acid methyl ester Hydrochloride	Others
	Methyl Aminolevulinate Hydrochloride (5-Aminolevulinic acid methyl ester) is commonly used in photosentizer reagents for photodynamic therapy to treat conditions such as Acne vulgaris and hypertrophic scarring.		Others
T81483	Photosensitizer-2
	Photosensitizer-2 (compound 1), an organic D-π-A sensitizer, exhibits antitumor properties and potent phototoxicity due to an acrylic acid moiety. It demonstrates significant activity against HeLa cells, with IC 50 value...
T75353	Photosensitizer-1 hydrochloride
	Photosensitizer-1 (Compound CLB-13) hydrochloride is a photosensitizer [1] .
T75352	Photosensitizer-1
	Photosensitizer-1 (Compound CLB-13) is a photosensitizer [1] .
T82997	Antitumor photosensitizer-2
	Compound 11, also known as Antitumor Photosensitizer-2, is a potent photosensitizer with remarkable photodynamic anti-tumor properties and minimal skin photo-toxicity, representing a promising candidate for photodynamic ...
T82998	Antitumor photosensitizer-1
	Antitumor Photosensitizer-1 (Compound 8) is a potent photosensitizer with remarkable photodynamic anti-tumor properties and minimal skin photo-toxicity, positioning it as a promising new candidate for photodynamic therap...
T74392	Antimicrobial photosensitizer-1
	Antimicrobial Photosensitizer-1 demonstrates significant potential as an effective agent for treating infections caused by pathogenic microorganisms, with notable antimicrobial efficacy observed in S. aureus-infected mou...
T74601	Antitumor photosensitizer-3
	Antitumor Photosensitizer-3 (Compound I), a chlorin derivative, effectively induces apoptosis and necrosis in tumor cells upon exposure to 650 nm laser irradiation. This compound demonstrates reduced skin phototoxicity c...
T79711	Antitumor photosensitizer-4		Apoptosis
	Antitumor Photosensitizer-4 (compound 10b), a conjugate of dasatinib and imatinib, serves as a potent tyrosine kinase inhibitor (TKI) targeting ABCG2. This photosensitizer (PS) induces apoptosis and reactive oxygen speci...		Apoptosis
T17216	Valspodar	PSC 833	P-gp
	Valspodar (PSC 833) is a specific P-glycoprotein inhibitor and MDR regulator often used as a chemical sensitizer to study advanced epithelial ovarian cancer.		P-gp
T25372	EMD57033	EMD-57033,(+)-EMD 57033,EMD 57033	Calcium Channel , Carbonic Anhydrase
	EMD57033 is a cardiac troponin C (cTnC) activator, a dominant Ca2+ sensitizer, which functions by binding to cardiac/slow skeletal troponin C heterodimers to promote cardiac contraction.		Calcium Channel , Carbonic Anhydrase
T27303	Farglitazar	GI-262570,GI-2570,GW 262570X,GI 262570,GI262570	PPAR
	Farglitazar (GI-262570) is a PPAR-γ agonist and insulin sensitizer that inhibits stellate cell activation by activating receptor γ via oxidative enzymes proliferators and is used in the study of diabetes.		PPAR
T4639	Azemiglitazone	MSDC 0602	Mitochondrial Metabolism , mTOR
	Azemiglitazone (MSDC 0602) is an insulin sensitizer potentially for the treatment of diabetes.		Mitochondrial Metabolism , mTOR
T0334	Rosiglitazone	BRL49653	Ferroptosis , TRP/TRPV Channel , PPAR , Autophagy
	Rosiglitazone (BRL49653) is a PPARγ agonist, TRPC5 activator, and TRPM3 inhibitor with oral activity. Rosiglitazone is also a hypoglycemic agent and a thiazolidinedione insulin sensitizer.		Ferroptosis , TRP/TRPV Channel , PPAR , Autophagy
T38715	MSDC-0602K	MSDC-0602K,Azemiglitazone potassium	PPAR
	MSDC-0602K (Azemiglitazone potassium) (Azemiglitazone potassium) is a PPARγ-sparing thiazolidinedione (Ps-TZD) compound that binds to PPARγ with an IC50 of 18.25 μM. It also modulates the mitochondrial pyruvate carrier (...		PPAR
T26585	AK301	AK-301,AK 301	Apoptosis , Microtubule Associated
	AK301 is a potent and selective inhibitor of tubulin polymerization and an effective sensitizer of cancer cells to apoptotic ligands (EC50 < 200 nM). Colon cancer cells arrested in mitosis with AK301 readily underwent a ...		Apoptosis , Microtubule Associated