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Farglitazar

Catalog No. T27303 CAS 196808-45-4

Synonyms: GI-262570, GI-2570, GW 262570X, GI 262570, GI262570

Farglitazar (GI-262570) is a PPAR-γ agonist and insulin sensitizer that inhibits stellate cell activation by activating receptor γ via oxidative enzymes proliferators and is used in the study of diabetes.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Farglitazar, CAS 196808-45-4

Pack Size	Availability	Price/USD
1 mg	In stock	$ 293.00
5 mg	In stock	$ 722.00
10 mg	In stock	$ 987.00
25 mg	In stock	$ 1,520.00
50 mg	6-8 weeks	$ 1,980.00

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Purity: 99.40%

ee: 100%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Synonyms	GI-262570, GI-2570, GW 262570X, GI 262570, GI262570
Molecular Weight	546.612
Formula	C34H30N2O5
CAS No.	196808-45-4

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Reynolds DW, et al. The Degradation Chemistry of Farglitazar and Elucidation of the Oxidative Degradation Mechanisms. J Pharm Sci. 2017 Apr;106(4):982-993. 2. McHutchison J,vine R, et al; Farglitizar Study Investigators. Farglitazar lacks antifibrotic activity in patients with chronic hepatitis C infection. Gastroenterology. 2010 Apr;138(4):1365-73, 1373.e1-doi: 10.1053/j.gastro.2009.12.003. Epub 2010 Feb 13. Erratum in: Gastroenterology. 2010 Jul;139(1):360. 3. Tenenbaum A,et al. Dual and pan-peroxisome proliferator-activated receptors (PPAR) co-agonism: the bezafibrate lessons. Cardiovasc Diabetol. 2005 Sep 16;4:14. 4. Spraggs C,et al. Genetic variants in the epithelial sodium channel associate with oedema in type 2 diabetic patients receiving the peroxisome proliferator-activated receptor gamma agonist farglitazar. Pharmacogenet Genomics. 2007 Dec;17(12):1065-76.

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Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Farglitazar 196808-45-4 DNA Damage/DNA Repair Metabolism PPAR GI-262570 GI-2570 GW 262570X GI 262570 GI262570 inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.