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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T82715 | Cisplatin-resistant cells-IN-1 | ||
Cisplatin-resistant cells-IN-1 (Compound 8) exhibits high cytotoxicity against Cisplatin-resistant cells and effectively diminishes metabolic activity at low nanomolar concentrations, with an IC50 ranging from 0.14 to 1.... | |||
TN4660 | Niranthin | Anti-infection , HBV , PAFR , Topoisomerase | |
Niranthin is a potent anti-leishmanial agent, inhibits the relaxation activity of heterodimeric type IB topoisomerase of L. donovani and acts as a non-competitive inhibitor interacting with both subunits of the enzyme. N... | |||
T24729 | Roseoflavin | Antibacterial | |
Roseoflavin, a chemical analog of FMN and riboflavin that has antimicrobial activity, can directly bind to FMN riboswitch aptamers and downregulate the expression of an FMN riboswitch-lacZ reporter gene in B. subtilis. | |||
T4989 | Fosfomycin Tromethamine | Antibacterial , Antibiotic | |
An antibiotic produced by Streptomyces fradiae. | |||
T8722 | IKIX1 | Antifungal | |
iKIX1 is an Pdr1-dependent gene activation. It re-sensitizes drug-resistant C. glabrata to azole antifungals in vitro and in animal models for disseminated and urinary tract C. glabrata infection. | |||
TN6512 | Tectol | Transferase , Parasite | |
Tectol has anti-plasmodial activity, it as a moderately active growth inhibitor with an IC50 3.44±0.20μM. It exhibited significant activity against human leukemia cell lines HL60 and CEM. Tectol may cause itchy dermatiti... | |||
T11888 | LtaS-IN-1 | Others , Antibacterial | |
LtaS-IN-1 is an effective inhibitor of Lipoteichoic acid synthesis in multidrug-resistant (MDR) E. faecium and by altering the cell wall morphology. LtaS-IN-1 is against Enterococcus spp 28 strains with varying MIC value... | |||
T8866 | GW779439X | Apoptosis , Antibacterial , CDK , Aurora Kinase | |
GW779439X is an inhibitor of CDK. | |||
T8262 | Fosfomycin sodium | Fosfomycin Disodium | Antibacterial , Antibiotic |
Fosfomycin sodium is a bactericidal, low-molecular weight, broad-spectrum antibiotic, with putative activity against several bacteria, including multidrug-resistant Gram-negative bacteria, by irreversibly inhibiting an e... | |||
T8217 | Enzalutamide carboxylic acid | Androgen Receptor , Drug Metabolite | |
Enzalutamide carboxylic acid is an antagonist of androgen receptor (AR) . | |||
T3131 | Fosfomycin calcium | Phosphomycin calcium salt,Fosmicin | Antibacterial , Antibiotic |
Fosfomycin calcium (Phosphomycin calcium salt) is a blood-brain barrier penetrating, broad-spectrum antibiotic by irreversibly inhibiting an early stage in cell wall synthesis. | |||
TN2027 | Oxysanguinarine | 8-Oxosanguinarine,Hydroxysanguinarine | Parasite |
Oxysanguinarine (Hydroxysanguinarine) possesses antiplatelet aggregation activity, it has potential inhibitory properties against the dengue virus. | |||
T6889 | MI-136 | Apoptosis , Epigenetic Reader Domain , Androgen Receptor | |
MI-136 inhibits expression of androgen receptor (AR) target genes that DHT induced. | |||
T64338 | AKI603 | AKI 603,AKI-603 | Aurora Kinase |
AKI603 is a novel small molecule inhibitor of Aurora kinase A (AurA)(IC50 = 12.3 nM). AKI603 is developed to overcome resistance mediated by BCR-ABL-T315I mutation. AKI603 exhibits strong anti-proliferative activity in l... | |||
T19721 | Epoxiconazole | BAS-480F,BAS 480F,EC 406 850 2,BAS480F,EC-406-850-2 | Antifungal |
Epoxiconazole (BAS-480F) is a 14-α demethylase inhibitor. It inhibits ergosterol synthesis and fungal cell wall formation. | |||
T24557 | NSC756093 | NSC-756093,NSC 756093 | Others |
NSC756093 potentially inhibits GBP1:PIM1 interaction. NSC756093 can be used in ovarian cancer studies. | |||
T9014 | SKI-178 | Apoptosis , S1P Receptor | |
SKI-178 is a sphingosine kinase 1 (SphK1) inhibitor with IC50 of 0.1-1.8 μM. It induces prolonged mitosis followed by apoptotic cell death through the intrinsic apoptotic cascade. The sustained activation of CDK1 during ... | |||
T22263 | Bavdegalutamide | ARV-110 | Androgen Receptor |
Bavdegalutamide (ARV-110) is a PROTAC degrader of androgen receptor (AR). Bavdegalutamide can be used in studies about prostate cancer. Bavdegalutamide shows oral activity and selectivity and facilitates the ubiquitinati... | |||
T7700 | Lersivirine | Lersivirine(UK 453061),UK-453061 | HIV Protease , Reverse Transcriptase |
Lersivirine (UK-453061)(UK 453061) is a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) under development for HIV infection therapy. | |||
T9246 | JNJ-63576253 | Androgen Receptor | |
JNJ-63576253 is a Clinical Stage Androgen Receptor Antagonist for F877L Mutant and Wild-Type Castration-Resistant Prostate Cancer (mCRPC). |