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Oxysanguinarine
🥰Excellent
Catalog No. TN2027Cas No. 548-30-1
Alias Hydroxysanguinarine, 8-Oxosanguinarine
Oxysanguinarine (Hydroxysanguinarine) possesses antiplatelet aggregation activity, it has potential inhibitory properties against the dengue virus.
Oxysanguinarine
🥰Excellent
Purity: 99.57%
Catalog No. TN2027Alias Hydroxysanguinarine, 8-OxosanguinarineCas No. 548-30-1
Oxysanguinarine (Hydroxysanguinarine) possesses antiplatelet aggregation activity, it has potential inhibitory properties against the dengue virus.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $55 | In Stock | |
| 5 mg | $147 | In Stock | |
| 10 mg | $239 | In Stock | |
| 25 mg | $395 | In Stock | |
| 50 mg | $589 | In Stock |
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Purity:99.57%
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Product Introduction
Bioactivity
Chemical Properties
| Description | Oxysanguinarine (Hydroxysanguinarine) possesses antiplatelet aggregation activity, it has potential inhibitory properties against the dengue virus. |
| In vitro | A total of 2750 phytochemicals from different medicinal plants were selected for this study. These plants grow naturally in the climate of Pakistan and India and have been used for the treatment of various pathologies in humans for a long-time. The ADMET studies, molecular docking and density functional theory (DFT) based analysis was carried out to determine the potential inhibitory properties of these phytochemicals. The ADMET analysis and docking results revealed nine phytochemicals, i.e. Silymarin, Flavobion, Derrisin, Isosilybin, Mundulinol, Silydianin, Isopomiferin, Narlumicine and Oxysanguinarine to have potential inhibitory properties against DENV and can be considered for additional in vitro and in vivo studies to assess their inhibitory effects against DENV replication. They exhibited binding affinity ≥ -8 kcal/mol against DENV4-NS4B. Furthermore, DFT-based analysis revealed high reactivity for these nine phytochemicals in the binding pocket of DENV4-NS4B, based on ELUMO, EHOMO and band energy gap. INTERPRETATION &[1] |
| Alias | Hydroxysanguinarine, 8-Oxosanguinarine |
| Molecular Weight | 347.32 |
| Formula | C20H13NO5 |
| Cas No. | 548-30-1 |
| Smiles | CN1C=2C(C=3C(C1=O)=C4C(=CC3)OCO4)=CC=C5C2C=C6C(=C5)OCO6 |
| Relative Density. | 1.509 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMF: < 1 mg/mL (slightly soluble)  Methanol: Insoluble Ethanol: Insoluble DMSO: Insoluble |
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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