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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T13047 | Synta66 | Calcium Channel | |
Synta66 is a store-operated calcium entry channel Orai inhibitor, and used for the research of neurological disease. | |||
T10885 | CRAC intermediate 2 | Others , Calcium Channel | |
CRAC intermediate 2 is a intermediate compound for CRAC inhibitor synthesis. | |||
T24984 | 5J-4 | Calcium Channel | |
5J-4 is a potent a blocker of calcium release-activated calcium (CRAC) channel and store-operated calcium entry (SOCE). 5J-4 reduces the production of IL-17 and decreases the expression of RORα and RORγt. | |||
T10884 | CRAC intermediate 1 | 5-(S)-Fluorowillardiine | Calcium Channel |
CRAC intermediate 1 (5-(S)-Fluorowillardiine) is a key intermediate in the chemical synthesis of a series of CRAC channel inhibitors. | |||
T3651 | YM-58483 | YM 58483,BTP2 | Calcium Channel |
YM-58483 (BTP2) is a specific and effective inhibitor of CRAC channels and subsequent Ca2+ signals. | |||
T25049 | Allethrin | BCL , Caspase | |
Allethrin induces oxidative stress, apoptosis and calcium release. Allethrin, a pyrethroid insecticide is a major mosquito repellent agent. | |||
T9000 | Pyrimorph | Antifungal | |
Pyrimorph is a fungicide with high activity against the plant pathogen Phytophthora capsici. Pyrimorph inhibited different stages in the life cycle of P. capsici including mycelial growth, sporangium production, zoospore... | |||
TN1213 | 2-(Hydroxymethyl)anthraquinone | Anti-infection | |
2-(Hydroxymethyl)anthraquinone exhibits strong activity against Helicobacter pylori ATCC 43504 at 0.01 mg/disc. | |||
T8867 | RO2959 Hydrochloride | RO2959 HCl | IL Receptor , Calcium Channel , Interleukin |
RO2959 Hydrochloride (RO2959 HCl) is a potent and selective inhibitor of CRAC channel(IC50: 402 nM). It is also a potent inhibitor of human IL-2. | |||
T2343 | AS601245 | JNK | |
AS601245 is an inhibitor of the c-Jun NH2-terminal kinase (JNK), with neuroprotective properties. | |||
TQ0033 | Zegocractin | CM-4620,N-(5-(6-Chloro-2,2-difluorobenzo[d][1,3]dioxol-5-yl)pyrazin-2-yl)-2-fluoro-6-methylbenzamide,CM4620 | Calcium Channel |
Zegocractin (CM-4620) is a calcium-release activated calcium-channel (CRAC channel) inhibitor. | |||
T6800 | CCF642 | AC1LYELL | Others |
CCF642 (AC1LYELL) is a novel PDI-inhibiting compound with antimyeloma activity. | |||
T2946 | Tanshinone IIA sulfonate sodium | Tanshinone IIA sulfonate,Sodium Tanshinone IIA sulfonate,Tanshinone IIA sodium sulfonate,sodium | CaMK , P450 , Calcium Channel |
Tanshinone IIA sulfonate sodium (Tanshinone IIA sodium sulfonate) is a water-soluble derivative of tanshinone IIA extracted from Savia miltiorrhiza; a potent negative allosteric modulator of the human purinergic receptor... | |||
T11217 | Eplivanserin | SR-46349 | 5-HT Receptor |
Eplivanserin (SR-46349) is an effective and selective antagonist of 5-HT2A receptor with a Kd of 1.14 nM and an IC50 value of 5.8 nM in rat cortical membrane. | |||
T2170 | SKF-96365 hydrochloride | SKF96365 | Apoptosis , Potassium Channel , Calcium Channel , TRP/TRPV Channel , Autophagy |
SKF-96365 hydrochloride (SKF96365) , a SOCE inhibitor, exhibits potent anti-neoplastic activity by inducing cell-cycle arrest and apoptosis in colorectal Y cells. SKF-96365 hydrochloride can induce cytoprotective autopha... | |||
T1198 | Tetracaine hydrochloride | Amethocaine hydrochloride,Amethocalne HCl,Tetracaine HCl | Calcium Channel , Sodium Channel |
Tetracaine hydrochloride (Amethocalne HCl) (Pontocaine), a potent local anaesthetic, is a channel function allosteric inhibitor. It is primarily used as an antipruritic and topically in ophthalmology, and it has been use... | |||
T6928 | Pantoprazole | SKF96022,BY1023 | Apoptosis , Proton pump , Autophagy |
Pantoprazole (BY1023) is a proton pump inhibitor used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal reflux disease. | |||
T0161 | Pantoprazole Sodium Hydrate | SKF96022 sodium hydrate,BY1023 (sodium hydrate),SKF96022 (sodium hydrate) | Apoptosis , Potassium Channel , Proton pump , Autophagy |
Pantoprazole Sodium Hydrate (BY1023 (sodium hydrate)) is a proton pump inhibitor drug, used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal reflux disease. | |||
T6929 | Pantoprazole sodium | Pantecta,SKF96022 sodium,SKF96022 (sodium),BY1023 (sodium),BY-1023 sodium,Pantoloc | Apoptosis , Others , Proton pump , HIF , Autophagy |
Pantoprazole sodium (Pantecta) is the sodium salt form of a substituted benzimidazole with proton pump inhibitor activity. Pantoprazole sodium is a lipophilic, weak base that crosses the parietal cell membrane and enters... | |||
T23434 | GPR35 agonist 2 | TC-G 1001 | GPR , Arrestin |
GPR35 agonist 2 (TC-G 1001) is a potent GPR35 agonist.The EC50 values of GPR35 agonist 2 in the β-arrestin and Ca2+ release assays were 26 and 3.2 nM, respectively. |