p50 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
TWS1977	Kamebakaurin	Kamebakaurine	NF-κB
	1. Kamebakaurin (Kamebakaurine) has the ability to protect the liver from APAP-induced hepatotoxicity, presumably by both inhibiting the inflammatory response and oxidative stress. 2. Kamebakaurin inhibits the expression...		NF-κB
T13336	VTP50469		Apoptosis , Epigenetic Reader Domain , Histone Methyltransferase
	VTP50469 is a highly selective and orally active inhibitor of Menin-MLL interaction( Ki: 104 pM) and has potently anti-leukemia activity.
T24584	P505-15 Acetate	PRT 062607 Acetate,P505 15 Acetate,PRT-062607 Acetate,PRT062607 Acetate,P50515 Acetate	Tyrosinase
	P505-15 Acetate is a selective inhibitor of spleen tyrosine kinase that acts by suppressing leukocyte immune function and inflammation and leading to a reduction in arthritis score and attenuated histological damage.		Tyrosinase
TP1853	TP508
	TP508 is a 23 amino acid synthetic peptide representing residues 508-530 of human prothrombin which is identified as a potential receptor-binding domain based on competition for high-affinity thrombin binding to fibrobla...
T69091	CBP501
	CBP501 is a peptide with G2 checkpoint-abrogating activity. G2 checkpoint inhibitor CBP501 inhibits multiple serine/threonine kinases, including MAPKAP-K2, C-Tak1, and CHK1, that phosphorylate serine 216 of the dual-spec...
T72785	PRMT5:MEP50 PPI
	PRMT5:MEP50 PPI, a pioneering inhibitor of the PRMT5:MEP50 protein-protein interaction (PRMT5:MEP50 PPI), demonstrates anti-tumor and anti-proliferative effects in lung and prostate cancer cells.
T13336L	VTP50469 fumarate		Others
	VTP50469 fumarate is a highly selective and orally active inhibitor of Menin-MLL interaction (Ki: 104 pM), and has potently anti-leukemia activity.		Others
T80132	CBP501 Affinity Peptide
	CBP501 Affinity Peptide, a Chk kinase inhibitor, disrupts G2 arrest triggered by DNA-damaging agents and is utilized in cancer research [1].
T75763	TP508 TFA
	TP508 TFA, a 23-amino acid segment of the thrombin molecule's receptor-binding domain, is a nonproteolytic thrombin peptide. It activates endothelial NO synthase (eNOS) to enhance nitric oxide (NO) production in human en...
T69846	VTP50469 mesylate
	VTP-50469 is a novel, potent, selective, orally-available MeninMLL1 inhibitor, being effectively against MLL-rearranged and NPM1c+ leukemia, selectively killing cell lines with MLLrearrangements and NPM1c+ mutations.
T24736	RP5063 Hydrochloride	RP-5063 HCl,RP 5063 HCl,RP 5063 Hydrochloride,RP-5063 Hydrochloride,RP5063 HCl
	RP5063 Hydrochloride is a modulator of multimodal serotonin receptors.
TP2164	TP508 TFA (121341-81-9 free base)	TP508 TFA	Others
	TP508 TFA is a nonproteolytic thrombin peptide. TP508 TFA activates endothelial NO synthase (eNOS) and stimulates the production of NO in human endothelial cells. It activates endothelial cells and stem cells to revascul...		Others
T62657	SHP504
	SHP504 is an inhibitor of SHP2 phosphatase and acts on SHP21-525 (IC50: 21 μM).
T3012	Mangiferin	Alpizarin,Chinomin,Hedysarid	Apoptosis , Others , NF-κB , Nrf2
	Mangiferin (Hedysarid) is used for antidiabetes. Extracted from Mangifera indica L.		Apoptosis , Others , NF-κB , Nrf2
TN3922	Effusanin E		PARP , NF-κB , Caspase , COX , Antifection
	Effusanin E shows antibacterial and anti-cancer activities, it significantly inhibits cell proliferation and induces apoptosis in NPC cells by suppressing p50/p65 proteins to down-regulate COX-2 expression .		PARP , NF-κB , Caspase , COX , Antifection
T78846	EP12		Apoptosis
	EP12, a c-Myc inhibitor and G4 stabilizer, induces apoptosis and DNA damage in multiple myeloma cells while obstructing P65/P50 nuclear translocation by disrupting the NF-κB signaling pathway, effectively inhibiting mult...		Apoptosis
T38153	NF-κB Inhibitor (trifluoroacetate salt)
	NF-κB inhibitor is a synthetic peptide corresponding to the nuclear localization sequence of NF-κB p105 subunit (also known as p50) appended to a hydrophobic sequence to facilitate import into living cells.1It blocks the...
T37559	NF-κB Control
	NF-κB inhibitor is a synthetic peptide corresponding to the nuclear localization sequence (NLS) of NF-κB p105 subunit (also known as p50) appended to a hydrophobic sequence to facilitate import into living cells. It bloc...
TN4635	Neoechinulin A		NADPH-oxidase , Beta Amyloid , ASK , IκB/IKK , p38 MAPK , TNF , NOS , NF-κB , COX , Prostaglandin Receptor
	Neoechinulin A has anti-inflammatory effect against LPS-stimulated RAW264.7 macrophages through inhibition of the NF-ÎºB and p38 MAPK pathways, it may block the phosphorylation of mitogen-activated protein kinase (MAPK) ...