neurotoxic — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T9169	MPP+ iodide		Mitochondrial Metabolism , Autophagy
	MPP+ iodide, the metabolite of a neurotoxin MPTP, causes symptom of Parkinson's disease (PD) in animal models by selectively destroying dopaminergic neurons in substantia nigra. MPP+ induces dopamine transporter (DAT) ex...		Mitochondrial Metabolism , Autophagy
T15391	Glufosinate ammonium		Others
	Glufosinate ammonium is a phosphinic acid analog of glutamic acid and an herbicide with neurotoxic activity. It is converted by plant cells into PT (L-phosphinothricin).		Others
T20812	Azamethiphos		AChE
	Azamethiphos, an organothiophosphate insecticide, is used in Atlantic salmon fish farming to control parasites.		AChE
T19412	Macrozamin		Others
	Macrozamin has carcinogenic, mutagenic, teratogenic and neurotoxic properties.Macrozamin is a natural product isolated from Cycads.		Others
T6953	Prilocaine	Citanest,Propitocaine,NSC 40027	ATPase , Sodium Channel
	Prilocaine (NSC-40027) is a local anesthetic of the amino amide type, which acts on the sodium channel on the neuronal membrane and limits the spread of seizures.		ATPase , Sodium Channel
T0796	Prilocaine hydrochloride	Prilocaine HCl,Propitocaine hydrochloride,Xylonest	ATPase , Sodium Channel
	Prilocaine hydrochloride (Prilocaine HCl) is a local anesthetic of the amino amide type, binds to voltage-gated sodium ion channels in the neuronal membrane, thereby preventing the permeability of sodium ions.		ATPase , Sodium Channel
T0787	Butylhydroxyanisole	BHA,E320,Butylated hydroxyanisole	Antioxidant , Ferroptosis , Reactive Oxygen Species
	Butylhydroxyanisole (BHA) is an antioxidant consisting of a mixture of two isomeric organic compounds, 2-tert-butyl-4-hydroxyanisole and 3-tert-butyl-4-hydroxyanisole.		Antioxidant , Ferroptosis , Reactive Oxygen Species
T6820	D-α-Hydroxyglutaric acid disodium	D-alpha-Hydroxyglutaric acid disodium salt,Disodium (R)-2-Hydroxyglutarate	ATPase , Others , Reactive Oxygen Species , Endogenous Metabolite , mTOR
	D-α-Hydroxyglutaric acid disodium (Disodium (R)-2-Hydroxyglutarate) is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases with Ki of 0.628 mM.
T1100	Polymyxin B Sulfate	Aerosporin,PMB,Polymyxin B sulphate,Polymyxin B sulfate (1404-26-8 free base),Poly-RX	Antibacterial , Antibiotic
	Polymyxin B Sulfate (Poly-RX) is a mixture of polymyxins B1 and B2, obtained from Bacillus polymyxa strains. They are basic polypeptides of about eight amino acids and have cationic detergent action on cell membranes. Po...		Antibacterial , Antibiotic
T14284	β-Amyloid (25-35)	β-Amyloid peptide(25-35),Aβ25-35,Amyloid beta-peptide(25-35)	Beta Amyloid
	β-Amyloid (25-35) (Aβ25-35) is the fragment Aβ(25-35) of the Alzheimer's amyloid β-peptide. Which has shown neurotoxic activities in cultured cells.		Beta Amyloid
T15027	Cyclopiazonic acid		Calcium Channel
	Cyclopiazonic acid (CPA) is a neurotoxic secondary metabolite (SM) made by A. flavus. Cyclopiazonic acid (CPA) is an endoplasmic reticulum calcium ATPase (Ca2+ATPase; SERCA)nanomolar inhibitor and a potent inducer of ce...		Calcium Channel
T20754	Deltamethrin	Butoss,RU-22974,Esbecythrin,K-Othrin,Decamethrin,RU 22974	Others
	Deltamethrin (RU 22974), a neurotoxic pyrethroid insecticide, produces a reversible sequence of motor symptoms in rats involving hind limb rigidity and choreoathetosis.Deltamethrin is globally used in crop protection, co...		Others
T9504	MAP4343		Microtubule Associated
	Map4343 is a 3-methyl ether derivative of pregnenolone. Map4343 binds to microtubule associated protein 2 (MAP2) in vitro and stimulates tubulin polymerization, resulting in enhanced neurite extension and protection of n...		Microtubule Associated
TL0001	Dencichine	L-Dencichin,ODAP,Dencichin	Others , HIF/HIF Prolyl-Hydroxylase
	Dencichine (ODAP) is a neurotoxic agent. Dencichine is a haemostatic agent, the hemostatic effect relates to modulation of the coagulation system, platelet aggregation and fibrinolytic system. It has renoprotective effec...		Others , HIF/HIF Prolyl-Hydroxylase
T13664	DSP-4 hydrochloride	Neurotoxin DSP 4 (hydrochloride)	Others
	DSP-4 hydrochloride (Neurotoxin DSP 4 (hydrochloride)) (Neurotoxin DSP 4 hydrochloride) can be used for the temporary selective degradation of the central and peripheral noradrenergic neurons, mainly those from the locus...		Others
TN1831	Macranthoside A	Kalopanaxsaponin H	Antioxidant
	Macranthoside A (Kalopanaxsaponin H) is a triterpenoid glycoside extracted from rehmannia and belongs to the iridoterpenoid synthesis. Macranthoside A has anti-inflammatory, antioxidant, antibacterial and neuroprotective...		Antioxidant
T36356	T-Peptide
	Highly neurotoxic cell-permeable analog of PHF6. Induces aggregation of Tau peptides.
T40627	Trichodesmine
	Trichodesmine, a dehydropyrrolizidine alkaloid, exhibits hepatotoxic, pneumotoxic, and neurotoxic effects in vivo.
T20396	Levadopa Related Compound A	6-Hydroxydopa, L-,L-Hydroxydopa
	Levadopa Related Compound A is the 6-hydroxy derivative of the amino acid L-DOPA with neurotoxic properties. Exogenously administered 6-Hydroxy-L-DOPA is biotransformed by an amino acid decarboxylase to the highly potent...
T15391L	Glufosinate		Others
	Glufosinate, a phosphinic acid analog of glutamic acid, is a herbicide that is converted by plant cells into PT (L-phosphinothricin). It has neurotoxic activity.		Others