membrane-bound — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T8946	Indophagolin		P2X Receptor , 5-HT Receptor , Autophagy
	Indophagolin is a potent, indoline-containing autophagy inhibitor with IC50 of 140 nM. Indophagolin antagonizes the purinergic receptor P2X4 as well as P2X1 and P2X3 with IC50s of 2.71, 2.40 and 3.49 μM, respectively.		P2X Receptor , 5-HT Receptor , Autophagy
T80209	Human membrane-bound PD-L1 polypeptide		PD-1/PD-L1
	Human membrane-bound PD-L1 polypeptide serves as an antigen for inducing the production of PD-L1 antibodies [1].		PD-1/PD-L1
T35951	Alkaline Phosphatase		Others
	Alkaline Phosphatase is an ubiquitous membrane-bound glycoprotein that catalyzes the hydrolysis of phosphate monoesters at basic pH values.		Others
T0313	Evans blue	Direct Blue 53,C.I. 23860	GluR
	Evans blue (C.I. 23860) is an azo dye, inhibits L-glutamate uptake via the membrane-bound excitatory amino acid transporter (EAAT).		GluR
T77780	Zamaporvint	RXC004	Others
	Zamaporvint (RXC004) is a selective, orally active and potent inhibitor of the Wnt pathway that acts on the membrane-bound fatty acyltransferase porcupine to block Wnt ligand palmitoylation, secretion, and pathway activa...		Others
T36433	A2ti-2	A2ti-2	Virus Protease , Antiviral
	A2ti-2 is a low affinity and selective inhibitor of the membrane-bound protein A2/S100A10 heterotetramer (A2t) (IC50 : 230 μM).A2ti-2 exhibits antiviral activity by selectively disrupting protein interactions between A2 ...		Virus Protease , Antiviral
T4889	2,6-Diaminoheptanedioic acid		Others , Endogenous Metabolite
	Diaminopimelic acid or DAPA is a lysine-like amino acid derivative that is a key component of the bacterial cell wall. DAPA is incorporated or integrated into peptidoglycan of gram negative bacteria and is the attachment...		Others , Endogenous Metabolite
T28466	PSMA-11	HBED-CC-PSMA,Psma-hbed-CC,PSMA11
	PSMA-11 (HBED-CC-PSMA) detects prostate cancer recurrence and metastasis by binding to the extracellular structural domain of prostate-specific membrane antigen (PSMA).PSMA-11 is often used as a tracer of PSMA-expressing...
TN4697	Odoroside H		ATPase , Potassium Channel , Sodium Channel
	Odoroside H has anticancer activities, the cytotoxic effects are induced by the inhibition of the plasma membrane bound Na(+)/K(+)-ATPase.		ATPase , Potassium Channel , Sodium Channel
T69868	ZIKV-IN-K22
	ZIKV-IN-K22 is a potent antiviral agent against a broad range of coronaviruses by targeting membrane-bound viral RNA replication, effectively inhibiting ZIKV with IC50 of 2.1 μM.
T37871	Octaethylene glycol monododecyl ether
	C12E8 is a nonionic surfactant formed by the ethoxylation of dodecanol, yielding a compound with eight repeated units of ethylene glycol. It can be used for solubilization of membrane-bound proteins.
T81948	Latartoxin-1a	LtTx-1a
	Latartoxin-1a (LtTx-1a), a paralytic and lethal peptide toxin for insects with membrane-bound activity [1], can be isolated from L. tarabaevi.
TP2254	GTP-Binding Protein Fragment, G alpha		Others
	Using specific antisera raised against synthetic peptides, we find that three distinct GTP-binding protein alpha subunits remain bound to the plasma membrane even after activation with nonhydrolyzable GTP analog. Trypsin...		Others
T63291	Pranlukast hemihydrate
	Pranlukast hemihydrate is a selective, potent and competitive antagonist of leukotriene.Pranlukast inhibits [3H]LTE4 (Ki: 0.63±0.11 nM), [3H]LTD4 (Ki: 0.99±0.19 nM) and [3H]LTC4 (Ki: 5640 ±680 nM) were bound to the lung ...
T78432	Suc-AAPF-pNA	Suc-Ala-Ala-Pro-Phe-pNA
	Suc-AAPF-pNA (Suc-Ala-Ala-Pro-Phe-pNA), a chromogenic p-nitroanilide (pNA) substrate, exhibits a Km of 1.7 mM and is utilized for assessing both free and membrane-bound cathepsin G in human neutrophils [1].
T80587	Alunacedase alfa	HrsACE2,GSK 2586881	SARS-CoV
	Alunacedase alfa (HrsACE2; GSK 2586881), a genetically modified human recombinant soluble angiotensin-converting enzyme-2 (hrsACE2), inhibits SARS-CoV-2 cell entry by competing with membrane-bound ACE2, offering potentia...		SARS-CoV
T37118	ADP-Glucose (sodium salt)	ADPG,Adenosine-5'-diphosphoglucose,ADP-Glucose (sodium salt)
	ADP-Glucose (ADPG) is an immediate precursor used in the biosynthesis, by glucose addition, of storage polysaccharides in plants, green algae, and cyanobacteria, as well as structural polysaccharides in certain bacteria....
T76762	Tabalumab
	Tabalumab (LY2127399), a humanized monoclonal antibody (IgG4 type) targeting B-cell activating factor (BAFF), exhibits neutralizing activity against both membrane-bound and soluble BAFF. This compound is relevant for res...
T79753	HCAIX/XII-IN-8		Carbonic Anhydrase
	hCAIX/XII-IN-8 (compound 3g) is a potent inhibitor of the human carbonic anhydrases (CAs) IX and XII, with inhibition constants (K i) of 8.5 nM for CA IX and 6.7 nM for CA XII. It demonstrates significant inhibitory effi...		Carbonic Anhydrase
T37651	5(S),6(R)-11-trans DiHETE
	5(S),6(R)-11-trans DiHETE is a C-11 double bond isomer of 5(S),6(R)-DiHETE that is formed by the enzymatic isomerization of 5(S),6(R)-DiHETE by a membrane bound factor. 5(S),6(R)-11-trans DiHETE has been found in rat kid...