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2,6-Diaminoheptanedioic acid

Catalog No. T4889 CAS 583-93-7

Diaminopimelic acid or DAPA is a lysine-like amino acid derivative that is a key component of the bacterial cell wall. DAPA is incorporated or integrated into peptidoglycan of gram negative bacteria and is the attachment point for Braun's lipoprotein (BLP or Murein Lipoprotein). BLP is found in gram-negative cell walls and is one of the most abundant membrane proteins. BLP is bound at its C-terminal end (a lysine) by a covalent bond to the peptidoglycan layer (specifically to diaminopimelic acid molecules) and is embedded in the outer membrane by its hydrophobic head (a cysteine with lipids attached). BLP tightly links the two layers and provides structural integrity to the bacterial outer membrane. Diaminopimelic acid can be found in human urine or feces due to the lysis or enzymatic breakdown of gram negative gut microbes.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

2,6-Diaminoheptanedioic acid Chemical Structure

2,6-Diaminoheptanedioic acid, CAS 583-93-7

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100 mg	In stock	$ 35.00

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Purity: 99.95%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Molecular Weight	190.2
Formula	C7H14N2O4
CAS No.	583-93-7

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

H2O: 10 mM

DMSO: Insoluble

References and Literature

1. Lida S . Gordonia otitidis sp. nov. isolated from a patent with externarl otitis[J]. Int. J. Syst. Evol. Microbiol. 2005, 55. 2. Borruat G , Roten C A H , Fay L B , et al. A High-Performance Liquid Chromatography Method for the Detection of Diaminopimelic Acid in Urine[J]. Analytical Biochemistry, 2001, 291(1):11-16. 3. Hamaker B R , Rivera K , Morales E , et al. Effect of Dietary Fiber and Starch on Fecal Composition in Preschool Children Consuming Maize, Amaranth, or Cassava Flours[J]. J Pediatr Gastroenterol Nutr, 1991, 13(1):59-66.

Related compound libraries

This product is contained In the following compound libraries：

Microbial Natural Product Library Human Metabolite Library Natural Product Library Gut Microbial Metabolite Library Bioactive Compound Library Covalent Inhibitor Library Natural Product Library for HTS Anti-Infection Compound Library NO PAINS Compound Library RO5 Drug-like Natural Product Library

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Keywords

2,6-Diaminoheptanedioic acid 583-93-7 Metabolism Others Endogenous Metabolite 2,6 Diaminoheptanedioic acid Inhibitor inhibit 2,6Diaminoheptanedioic acid inhibitor

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