large — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
TP1830	SV40 large T antigen NLS
	SV40 large T antigen NLS is from Large T antigen residue 47 to 55, enables protein import into cell nucleus. This peptide is generated from Large T antigen residue 47 to 55.
TP1830L	SV40 large T antigen NLS acetate		Others
	SV40 large T antigen NLS acetate is from Large T antigen residue 47 to 55, enables protein import into cell nucleus.		Others
TP2183	Large T antigen - rhesus polyomavirus 560-568		Others
	Large T antigen - rhesus polyomavirus 560-568 has a peptide sequence of Ser-Glu-Phe-Leu-Leu-Glu-Lys-Arg-Ile. T antigen is required for viral DNA replication, transcription, and virion assembly.		Others
T10096L	Voruciclib		CDK
	Voruciclib is an orally active and selective CDK inhibitor (Ki: 0.626 nM-9.1 nM). Voruciclib represses the expression of MCL-1 in multiple models of diffuse large B-cell lymphoma. Voruciclib effectively blocks CDK9, the ...		CDK
T16040	Mepazine	Pecazine	Apoptosis , MALT
	Mepazine (Pecazine) is a potent and selective inhibitor of MALT1. Mepazine inhibits GSTMALT1 full length and GSTMALT1 325-760 with IC50s of 0.83 μM and 0.42 μM. Mepazine enhances apoptosis and affects the cell viability.		Apoptosis , MALT
T9203	JH-X-119-01		IRAK
	JH-X-119-01 is a highly potent and selective covalent inhibitor of IRAK-1.		IRAK
T14367	AZ1495		IRAK , CDK , Haspin Kinase
	AZ1495 is an oral active inhibitor of Interleukin-1 receptor associated kinase 4 (IRAK4), with IC50 values of 5 nM and 23 nM for IRAK4 and IRAK1, respectively. Which Shows activity in treatment of mutant MYD88L265P diffu...		IRAK , CDK , Haspin Kinase
T5354	IRAK4-IN-7	CA-4948	IRAK
	IRAK4-IN-7 (CA-4948) is a selective and potent IRAK4 kinase inhibitor with in vivo activity in a TLR4-induced cytokine release model.		IRAK
T3549	Avadomide	CC 122	Apoptosis , E1/E2/E3 Enzyme , Ligand for E3 Ligase
	Avadomide (CC 122) is an orally available pleiotropic pathway modulator with potential antineoplastic activity.		Apoptosis , E1/E2/E3 Enzyme , Ligand for E3 Ligase
T67940	WAY-329738
	WAY-329738 has antifungal activity and can be used to treat large fungal infections.
T12186	Navitoclax-piperazine	ABT-263-piperazine	BCL , Ligands for Target Protein for PROTAC
	Navitoclax-piperazine (ABT-263-piperazine) is an inhibitor of B-cell lymphoma extra large (BCL-XL).		BCL , Ligands for Target Protein for PROTAC
T7512	BMS-191011	BMS-A	Potassium Channel
	BMS-191011 (BMS-A) is an activator of large-conductance calcium-activated potassium (BKCa) channels ,effective in stroke models		Potassium Channel
T14125	Adarotene	ST1926	Apoptosis
	Adarotene (ST1926) is an effective apoptosis inducer. It surprisingly produces DNA damage and exhibits a potent antiproliferative activity on a large panel of human tumor cells.		Apoptosis
TP1309	Gastric mucin		Antibacterial , Antibiotic
	Gastric mucin is a large glycoprotein which is thought to play a major role in the protection of the gastrointestinal tract from acid, proteases, pathogenic microorganisms, and mechanical trauma.		Antibacterial , Antibiotic
T4294	NS 11021	NS11021	Potassium Channel
	NS 11021 (NS11021) , a novel opener of large-conductance Ca(2+)-activated K(+) channels		Potassium Channel
T22291	Chitin	Chitin (From shrimp and crab shells)	Others
	Chitin is a large, structural polysaccharide found in the cell walls of fungi, the exoskeletons of insects, and certain hard structures in fish and invertebrates.		Others
TN7211	Tetrahydroharmine	Leptaflorine	MAO
	Tetrahydroharmine (Leptaflorine) is a natural product found in the stems and large branches of Banisteriopsis caapi cultivar Da Vine. Tetrahydroharmine is a Monoamine oxidase A inhibitor.		MAO
T77135	Tafasitamab	MOR00208,XmAb5574,Tafasitamab-cxix	Apoptosis , Immunology/Inflammation related
	Tafasitamab (XmAb5574) is an FC-modified humanized monoclonal antibody targeting the human B-cell surface antigen CD19 for the study of diffuse large B-cell lymphoma.		Apoptosis , Immunology/Inflammation related
T35366	4-Nitroquinoline 1-oxide	4-Nitroquinoline 1-oxide,4Nqo,NQO,4-NQO,4-Nitroquinoline-N-oxide,NQNO	Others
	4-Nitroquinoline 1-oxide (4-NQO) is a chemical carcinogen that induces mutations in bacteria, fungi, and animals through the formation of large amounts of purine adducts.		Others
T8411	C-215		Others
	C-215 is a novel inhibitor of mycobacterial membrane protein large 3 (MmpL3).		Others