infiltration — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T8844	Diflapolin		Others , FLAP , Epoxide Hydrolase
	Diflapolin is a highly active dual 5-lipoxygenase-activating protein (FLAP)/soluble epoxide hydrolase (sEH) inhibitor with marked anti-inflammatory efficacy and high target selectivity.		Others , FLAP , Epoxide Hydrolase
T8313	HCH6-1		Others
	HCH6-1 is a competitive Formyl peptide receptor 1 (FPR1) antagonist.		Others
T9043	AS1810722		P450 , STAT
	AS1810722, a fused bicyclic pyrimidine derivative, is an orally active and potent inhibitor of STAT6, demonstrating an IC50 of 1.9 nM. It exhibits effective inhibition of CYP3A4, positioning it as a promising candidate f...		P450 , STAT
T1115	Doxylamine succinate	Decapryn	Histamine Receptor
	Doxylamine Succinate is a pyridine derivate histamine H1 antagonist with pronounced sedative properties. Doxylamine succinate (Decapryn) competitively blocks the histamine H1 receptor and limits the typical allergic and ...		Histamine Receptor
T0946	Mepivacaine hydrochloride	Mepivacaine HCl	Sodium Channel
	Mepivacaine hydrochloride (Mepivacaine HCl) is the hydrochloride salt form of mepivacaine, an amide derivative with local anesthetic properties.		Sodium Channel
T2018	Apilimod	STA 5326	IL Receptor , PI3K , Interleukin
	Apilimod (STA 5326) inhibits the production of IL-12 and IL-23 and reduces dendritic cell infiltration in psoriasis.		IL Receptor , PI3K , Interleukin
T35367	Thioacetamide	TAA	Others
	Thioacetamide is a hepatotoxicant used widely to induce experimental liver lesions, develops hepatocellular necrosis and subsequent inflammation (mainly M1-/M2-macrophages without neutrophil infiltration) in rats.		Others
T8857	LJP-1586 HCl	LJP 1586,LJP-1586 hydrochloride,LJP-1586,LJP1586	Others
	LJP-1586 HCl, a highly selective inhibitor of vascular adhesion protein-1 (VAP-1), exhibits antiinflammation effect by reducing adhesion molecule expression and immune cell infiltration after intracerebral hemorrhage (IC...		Others
T1787	Levobupivacaine		Sodium Channel
	Levobupivacaine is an amino-amide local anaesthetic drug belonging to the family of n-alkylsubstituted pipecoloxylidide. It is the S-enantiomer of bupivacaine. Levobupivacaine hydrochloride is commonly marketed by AstraZ...		Sodium Channel
T0029	Procaine	Duracaine,Spinocaine,Novocaine,Vitamin H3	Histone Demethylase , DNA/RNA Synthesis , Sodium Channel
	Procaine (Vitamin H3) is a local anesthetic of the ester type that has a slow onset and a short duration of action. It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block.		Histone Demethylase , DNA/RNA Synthesis , Sodium Channel
T3662	Eleutheroside E		NF-κB
	Eleutheroside E has anti-inflammatory effects by inhibiting NF-κB activities. Eleutheroside E significantly decreases the inflammatory cell infiltration, pannus formation, cartilage damage, bone erosion of CIA mice, the ...		NF-κB
T6831	Etretinate	Retinoid,Tegison,Etretinato,Ethyl etrinoate,Ro 10-9359	Apoptosis , Others
	Etretinate (Ro 10-9359) is an oral aromatic retinoid acid which is effective in psoriasis and other dermatological syndromes. It activates retinoid receptors, causing an induction of cell differentiation, inhibition of c...		Apoptosis , Others
T16379	Oglemilast	GRC 3886	PDE
	Oglemilast (GRC 3886) suppresses pulmonary cell infiltration, including eosinophilia and neutrophilia in vitro and in vivo. Oglemilast is an effective and orally active phosphodiesterase-4 (PDE4) inhibitor (IC50: 0.5 nM ...		PDE
T8732	CTPI-2		Others , Mitochondrial Metabolism
	CTPI-2 is an inhibitor of mitochondrial citrate carrier SLC25A1 with(KD : 3.5 μM). CTPI-2 inhibits glycolysis, PPARγ, and its downstream target the glucose transporter GLUT4. CTPI-2 exhibits anti-tumor activity.CTPI-2 ha...		Others , Mitochondrial Metabolism
T61356	CXCR2 antagonist 3
	CXCR2 antagonist 3 (compound 11h) is a highly effective antagonist of CXC chemokine receptor 2 (CXCR2). It displays potent activity in inhibiting neutrophil infiltration into the air pouch, with double-digit nanomolar po...
TP1379	KKI-5 TFA(97145-43-2 free base)	KKI-5 (TFA)
	KKI-5 (TFA) is a specific tissue kallikrein inhibitor.Kki-5 (TFA) can reduce breast cancer cell infiltration.
T25525	IDT
	IDT is an orally active TNFα modulator. It acts by altering neutrophil infiltration, improving cognition and diminishing tau and amyloid pathology in the 3xTgAD mouse model.
T70107	Olcorolimus
	Olcorolimus inhibits single allergen-induced allergic inflammation such as eosinophilic and lymphocytic infiltration and mRNA expression for interleukin (IL)-4 and IL-5
T70874	Vipoglanstat
	Vipoglanstat is a prostaglandin E synthase inhibitor and an anti-inflammatory. Vipoglanstat ameliorates leukocyte infiltration and lung injury resulting from both endotoxin-induced and sepsis-induced lung injury.
T16733	Resolvin E1	RvE1	Others
	Resolvin E1 is an effective endogenous pro-resolving mediator of inflammation. Resolvin E1 has unique counterregulatory actions that inhibit PMN transendothelial migration. Resolvin E1 also acts as an effective inhibitor...		Others