Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Oglemilast (GRC 3886) suppresses pulmonary cell infiltration, including eosinophilia and neutrophilia in vitro and in vivo. Oglemilast is an effective and orally active phosphodiesterase-4 (PDE4) inhibitor (IC50: 0.5 nM for PDE4D3). Oglemilast has the potential for inflammatory airway diseases.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 61.00 | |
5 mg | In stock | $ 148.00 | |
10 mg | In stock | $ 253.00 | |
25 mg | In stock | $ 387.00 | |
50 mg | In stock | $ 496.00 | |
100 mg | In stock | $ 723.00 |
Description | Oglemilast (GRC 3886) suppresses pulmonary cell infiltration, including eosinophilia and neutrophilia in vitro and in vivo. Oglemilast is an effective and orally active phosphodiesterase-4 (PDE4) inhibitor (IC50: 0.5 nM for PDE4D3). Oglemilast has the potential for inflammatory airway diseases. |
Targets&IC50 | PDE4D3:0.5 nM |
In vitro | For the PDE 4B1 and PDE 4D3 reporter cell lines, Oglemilast has EC50s of 11.4 nM, 4.4 nM, respectively[3]. |
Synonyms | GRC 3886 |
Molecular Weight | 516.3 |
Formula | C20H13Cl2F2N3O5S |
CAS No. | 778576-62-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 3.6 mg/mL (7 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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Oglemilast 778576-62-8 Metabolism PDE GRC-3886 GRC 3886 GRC3886 inhibitor inhibit