dephosphorylation — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T7955	EB-3D		Apoptosis , AMPK , AChR
	EB-3D is a potent and selective choline kinase alpha 1 (ChoKα1) inhibitor(IC50 : 1 μM).with anti-cancer activity.		Apoptosis , AMPK , AChR
TP1015	NFAT Inhibitor	VIVIT peptide	Others
	NFAT Inhibitor (VIVIT peptide) is a cell-permeable compound that selectively inhibits calcineurin-mediated dephosphorylation of NFAT.		Others
T16156	MT 63-78		Apoptosis , AMPK , mTOR
	MT 63-78 is a specific and effective direct AMPK activator (EC50: 25 μM). MT 63-78 blocks prostate cancer growth by inhibiting the lipogenesis and mTORC1 pathways. MT 63-78 has antitumor effects. MT 63–78 also causes cel...		Apoptosis , AMPK , mTOR
T8978	DD1	3,3'-Diamino-4'-methoxyflavone,HUN85111	Proteasome
	DD1 (HUN85111) is a proteasome inhibitor that induces human myeloid tumor-selective apoptosis.		Proteasome
T2208	Bacitracin Zinc	Bacitracin zinc salt,Zinc bacitracin	c-Met/HGFR , Antibacterial , Antibiotic
	Bacitracin Zinc is an antibiotic that interferes with the dephosphorylation of C55-isoprenyl pyrophosphate, interference for inhibition of cleavage of Tyr from Met-enkephalin(IC50=10 μM).		c-Met/HGFR , Antibacterial , Antibiotic
T24398	Lenaldekar	LDK	Akt , IGF-1R , S6 Kinase
	Lenaldekar (LDK) inhibits T-cell expansion and autoimmune encephalomyelitis. Lenaldekar causes dephosphorylation of members of the PI3 kinase/AKT/mTOR pathway and delays sensitive cells in late mitosis.		Akt , IGF-1R , S6 Kinase
T10927	Cyt-PTPε Inhibitor-1	Cyt-PTP\|A Inhibitor-1	Phosphatase , Src
	Cyt-PTPε Inhibitor-1 (A Inhibitor-1) is an inhibitor of cytosolic protein tyrosine phosphatase ε. Cyt-PTPε Inhibitor-1 blocks the dephosphorylation of c-Src and exhibits anti-osteoclastic activity.		Phosphatase , Src
T2185	L-Ascorbic acid 2-phosphate trisodium	L-Ascorbic acid 2-phosphate trisodium salt,Sodium L-ascorbyl-2-phosphate,Sodium ascorbyl phosphate,2-Phospho-L-ascorbic acid trisodium salt,Sodium ascorbyl monophosphate	Reactive Oxygen Species , c-Met/HGFR , Endogenous Metabolite
	L-Ascorbic acid 2-phosphate trisodium (Sodium ascorbyl phosphate) is used in biocatalytic dephosphorylation for electric power generation and electrochemical detection assays.
T16115	MLi-2		LRRK2
	MLi-2 is a structurally novel, highly potent, and selective LRRK2 kinase inhibitor with central nervous system activity. MLi-2 exhibits exceptional potency in a purified LRRK2 kinase assay in vitro (IC50 = 0.76 nM), a ce...		LRRK2
T37977	Succinyladenosine
	Succinyladenosine is a biochemical marker of adenylosuccinase (ASL) deficiency. It is formed through the dephosphorylation of intracellular adenylosuccinic acid (S-AMP) by cytosolic 5-nucleotidase [1].
T71648	CK37
	CK37 controls the biological activity of Choline Kinase-α. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
T40507	BTO-1
	BTO-1 is a compound known as a Polo-like kinase (Plk) inhibitor, commonly employed for its effectiveness in regulating processes involving phosphorylation and dephosphorylation.
T40445	Cyclocreatine
	Cyclocreatine, a Creatine analogue, exhibits potent bioenergetic protection by elevating ATP levels. It demonstrates the ability to traverse cell membranes, including the blood-brain barrier, wherein it undergoes phospho...
TN6419	Chamaejasmine
	Chamaejasmine could be a candidate drug for osteosarcoma and breast cancer chemoprevention, induces apoptosis in MG63 and HEp-2 cells by Akt inactivation and dephosphorylation of BAD. It inhibits Bcl-2 expression and ind...
T77934	PhosTAC7		PROTACs
	PhosTAC7, akin to PROTACs in promoting ternary complex formation, recruits a Ser/Thr phosphatase to a phosphosubstrate to facilitate dephosphorylation.		PROTACs
T72100	D-erythro-Sphingosine hydrochloride	Erythrosphingosine hydrochloride,trans-4-Sphingenine hydrochloride,erythro-C18-Sphingosine hydrochloride,Erythrosphingosine hydrochloride ; erythro-C18-Sphingosine hydrochloride ; trans-4-Sphingenine hydrochloride
	D-erythro-Sphingosine hydrochloride, also known as Erythrosphingosine, serves as a specific TRPM3 activator and induces retinoblastoma protein dephosphorylation.
T35937	D-myo-Inositol-1,5,6-triphosphate (sodium salt)
	The inositol phosphates are a family of mono- to poly-phosphorylated compounds that act as messengers, regulating cellular functions including cell cycling, apoptosis, differentiation, andmotility. D-myo-Inositol-1,5,6-t...
T28092	MPT0B206
	MPT0B206 is a novel tubulin polymerization inhibitor. MPT0B206 induced G2/M cell cycle arrest and the appearance of the mitotic marker MPM-2 in K562 and K562R cells, which is associated with the upregulation of cyclin B1...
T69091	CBP501
	CBP501 is a peptide with G2 checkpoint-abrogating activity. G2 checkpoint inhibitor CBP501 inhibits multiple serine/threonine kinases, including MAPKAP-K2, C-Tak1, and CHK1, that phosphorylate serine 216 of the dual-spec...
T69200	CGP74514A
	CGP74514A is a CDK1 inhibitor with potential anticancer activity. In U937 cells, CGP74514A - induced apoptosis (5 microM) became apparent within 4 hr and approached 100% by 24 hr. The pan- caspase inhibitor Boc-fmk and t...