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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T9782 | Cytochrome C | Others | |
Cytochrome C, a protein that belongs to class 1 of the c-type cytochrome family, exerts different functions depending on its cellular localization and the conditions in which it operates. | |||
T21688L | Cytochrome c - pigeon (88-104) Acetate | Cytochrome c - pigeon (88-104) Acetate (86579-06-8 Free base) | Others |
Cytochrome c - pigeon (88-104) Acetate (Cytochrome c - pigeon ) is specific for a peptide within the COOH-terminal sequence 88-1041. | |||
TP2237 | Cytochrome c fragment (93-108) | Others | |
Cytochrome c fragment (93-108) is a small heme protein found loosely associated with the inner membrane of the mitochondrion. | |||
TP1855 | Moth Cytochrome C (MCC) (88-103) | Moth Cytochrome C (MCC) 88-103 | |
Moth Cytochrome C (MCC) (88-103), derived from the carboxyl terminus of moth cytochrome c, induces positive selection of TCR transgenic thymocytes.This peptide is derived from the carboxyl terminus of moth cytochrome c. ... | |||
T3149 | Salvianolic Acid C | Others , P450 | |
Salvianolic Acid C is extracted from the root of Salvia miltiorrhiza, a perennial plant in the genus Salvia. | |||
T9503 | PHYTOSPHINGOSINE | Apoptosis | |
Phytosphingosine is a phospholipid with anticancer properties. In cancer cells, Phytosphingosine induces cell apoptosis through activation of caspase 8 and translocation of Bax. | |||
T40732 | TMPD dihydrochloride | ||
TMPD dihydrochloride is an active substrate of enzymatically convert redox and an electron donor for the reduction of heme peroxidases. | |||
T6260 | AMG-208 | AMG 208 | P450 , c-Met/HGFR |
AMG-208 is a highly selective c-Met inhibitor with IC50 of 9 nM. Phase 1. | |||
T22119 | NS3694 | Apoptosis | |
NS3694 is an inhibitor of apoptosis and inhibits apoptosome formation and caspase activation. | |||
T2770 | Gentiopicroside | Gentiopicrin | P450 , HCV Protease |
Gentiopicroside (Gentiopicrin), a naturally occurring iridoid glycoside, extracted from Gentiana manshurica Kitag, inhibits P450 activity, with an IC50 and a Ki of 61 μM and 22.8 μM for CYP2A6; has antianti-inflammatorya... | |||
T3811 | Ginsenoside C-K | Ginsenoside compound K,Ginsenoside K | P450 , cell cycle arrest , COX , NO Synthase |
Ginsenoside C-K (Ginsenoside K) is a bacterial metabolite of G-Rb1 exhibiting anti-inflammatory effects by reducing iNOS and COX-2. | |||
T1290 | Oxiconazole nitrate | Ro 13-8996 | Others , Antibiotic , Antifection , Antifungal |
Oxiconazole nitrate (Ro 13-8996) is the nitrate salt form of oxiconazole, a broad spectrum imidazole derivative with antifungal activity. Although the exact mechanism of action has yet to be fully elucidated, oxiconazole... | |||
T6S0923 | Hypericin | Hypericine,Cyclosan | Apoptosis , Antiviral , Influenza Virus , Tyrosine Kinases , Antibacterial , PKC |
1. Hypericin (Cyclosan) has antineoplastic activity. 2. Hypericin has antibiotic and antiviral activities. 3. Hypericin has antidepressive activity through inhibiting monoamine oxidase enzyme. 4. Hypericin inhibits RANKL... | |||
T15212 | Emamectin Benzoate | MK-244 | Apoptosis , Reactive Oxygen Species , GABA Receptor , Parasite |
Emamectin Benzoate (MK-244), by binding gamma-aminobutyric acid (GABA) receptor and glutamate-gated chloride channels disrupting nerve signals within arthropods, acts as a chloride channel activator. | |||
T9335 | 1,1'-Methylenedi-2-naphthol | Squoxin | Others |
1,1'-Methylenedi-2-naphthol target CYP2C19 - cytochrome P450 family 2 subfamily C member 19 (human). | |||
T1192 | Protoporphyrin IX | PPIX | Others , Endogenous Metabolite |
Protoporphyrin IX (PPIX) is a tetrapyrrole containing 4 methyl, 2 propionic and 2 vinyl side chains that is a metabolic precursor for hemes, cytochrome c, and chlorophyll. | |||
T5210 | BAI1 | Apoptosis , BCL | |
BAI1 (Bax channel blocker) is a potent inhibitor of Bax-mediated mitochondrial cytochrome C release (IC50: 0.52 μM). | |||
T14846 | Bz 423 | BZ48 | Apoptosis , BCL |
Bz 423 is a potent immunomodulator that induces apoptosis by activating Bax and Bak to induce mitochondrial outer membrane permeabilization and cytochrome c release.Bz 423 shows partial activity in a mouse model of lupus... | |||
T2S1086 | Nepitrin | Nepetin-7-glucoside | Antioxidant |
1. Nepitrin (Nepetin-7-glucoside) has antioxidant activity in human HL6 cells assessed as reduction of cytochrome-c release, DPPH free radical scavenging activity, and inhibition of TPA-induced free radical formation. | |||
T60186 | (S)-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-2-(pyrimidin-5-yl)-1,2,3,4-tetrahydroisoquinoline-7-carboxamide | Discoidin Domain Receptor (DDR) | |
MitoBloCK-6 is an effective inhibitor of Erv1/ALR with IC50 values of 900 nM and 700 nM, respectively. Additionally, MitoBloCK-6 inhibits Erv2 (IC50=1.4 μM). It induces apoptosis in hESCs by promoting the release of cyto... |