cleavage — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T1349	5-Fluorouridine		Others , DNA/RNA Synthesis
	5-fluorouridine is also known as FUrd, 5-Fluorouracil 1-beta-D-ribofuranoside, 5-Fur, or 5-Fluoro-uridine. 5-fluorouridine is a solid. This compound belongs to the pyrimidine nucleosides and analogues. These are compound...		Others , DNA/RNA Synthesis
T11665	Ionomycin calcium	SQ23377 calcium	Apoptosis , Calcium Channel , Antibacterial , Antibiotic , PKC
	lonomycin calcium is a potent, selective calcium ionophore and an antibiotic produced by Streptomyces conglobatus. also induces the activation of protein kinase C (PKC). Ionomycin calcium (SQ23377 calcium) is highly spec...
T2096	Framycetin sulfate	Neomycin Sulphate B,Framycetin sulphate	Antibacterial , Antibiotic
	Framycetin sulfate (Neomycin Sulphate B) belongs to aminoglycoside class of antibiotics that contain two or more aminosugars connected by glycosidic bonds.		Antibacterial , Antibiotic
T17143	Toyocamycin	Vengicide	Apoptosis , Others , IRE1 , Antibiotic , Antifungal
	Toyocamycin (Vengicide) is an adenosine analog produced by Actinomycete, acts as an XBP1 inhibitor, inhibits IRE1α-induced ATP-dependent XBP1 mRNA cleavage (IC50: 80 nM). Toyocamycin induces apoptosis.		Apoptosis , Others , IRE1 , Antibiotic , Antifungal
T11589	Hydroxycitric acid tripotassium hydrate	Potassium citrate monohydrate	ATP Citrate Lyase , HIF/HIF Prolyl-Hydroxylase , HIF
	Hydroxycitric acid tripotassium hydrate (Potassium citrate monohydrate) effectively inhibits stones formation and also inhibits HIF, and has antioxidation, anti-inflammation, and anti-tumor effects. Hydroxycitric acid tr...		ATP Citrate Lyase , HIF/HIF Prolyl-Hydroxylase , HIF
T0256	Citric acid trilithium salt tetrahydrate	Lithium citrate tribasic tetrahydrate,Trilithium citrate tetrahydrate	Dehydrogenase , GSK-3 , HIF/HIF Prolyl-Hydroxylase , Antibacterial , GluR
	Citric acid trilithium salt tetrahydrate (Lithium citrate tribasic tetrahydrate) , the active component of Lithium, is a medicine used in the therapy of psychiatric disease. It has shown the effects of signaling pathways...
T14522	Beaucage reagent		DNA/RNA Synthesis
	Beaucage reagent, which is found to be effective in causing DNA cleavage.		DNA/RNA Synthesis
T35187	XR 5944	XR-5944,MLN-944,MLN944,XR5944,MLN 944
	XR 5944 is an effective DNA binder that stabilizes topoisomerase-dependent cleavage and has shown superior efficacy in a variety of mouse and human tumor models.
T27864	LX-2931	LX 3305,LX2931,LX-3305,ACB20034,LX 2931,LX3305	S1P Receptor
	LX-2931(LX-3305) is a sphingosine-1-phosphate cleavage enzyme (S1P) inhibitor for the treatment of rheumatoid arthritis.		S1P Receptor
T30161	EN3356	AS N001,ASN-001	P450
	EN3356 is an orally available and selective inhibitor of steroidal 17-alpha-hydroxylase/C17,20 cleavage enzyme (CYP17A1 or CYP17), a non-steroidal cleavage enzyme-selective compound with potential anti-androgenic and ant...		P450
T11527L	H-Ser-His-OH acetate		Endogenous Metabolite
	H-Ser-His-OH acetate is an endogenous metabolite hydrolysis cleavage activity.		Endogenous Metabolite
T67887	BDCRB
	BDCRB inhibits herpesvirus DNA maturation. BDCRB causes the HCMV terminase to skip the normal cleavage site and to continue to package DNA until a second cleavage site is encountered 30 kb further along the concatemer.
T77627	Opevesostat	ODM208,ODM-208	P450
	Opevesostat (ODM-208) is an inhibitor of lyase (CYP11A1) (the enzyme cleavage cholesterol side chain).		P450
T20318	Benzylideneaniline	N-Benzylideneaniline	Others
	Benzylideneaniline (N-Benzylideneaniline) is a potent inhibitor of xyloglucan-α,β-dioxygenase, a key enzyme in the oxidative cleavage of the central double bond of xyloglucan.		Others
TP2180L	Compstatin control peptide acetate		Complement System
	Compstatin control peptide acetate is an inhibitor of complement protein C3 by binding and inhibiting the cleavage of complement C3.		Complement System
T21498	Phleomycin		DNA/RNA Synthesis , Antibacterial , Antibiotic
	Phleomycin is one of the anticancer glycopeptide antibiotics which cause DNA cleavage. It is similar to Bleomycin which binds and intercalates DNA to damage the integrity of the double helix.		DNA/RNA Synthesis , Antibacterial , Antibiotic
T1772	MDK83190	Apoptosis Activator 2	Apoptosis , Caspase
	MDK83190 (Apoptosis Activator 2) is a potent apoptosis activator, induceing caspase-3 activation, PARP cleavage, and DNA fragmentation .		Apoptosis , Caspase
TN1067	Galloylpaeoniflorin	6'-O-Galloyl paeoniflorin	NF-κB , Androgen Receptor , ROS
	Galloylpaeoniflorin (6'-O-Galloyl paeoniflorin) may be developed as a cytoprotector against ROS-mediated oxidative stress. Galloylpaeoniflorin is also an inhibtior of NF-κB and DNA cleavage.		NF-κB , Androgen Receptor , ROS
TP1835L	Enterostatin, human, mouse, rat acetate		Endogenous Metabolite
	Enterostatin, human, mouse, rat acetate is a pentapeptide mainly formed in the intestine by the cleavage of secreted pancreatic procolipase.		Endogenous Metabolite
T2208	Bacitracin Zinc	Bacitracin zinc salt,Zinc bacitracin	c-Met/HGFR , Antibacterial , Antibiotic
	Bacitracin Zinc is an antibiotic that interferes with the dephosphorylation of C55-isoprenyl pyrophosphate, interference for inhibition of cleavage of Tyr from Met-enkephalin(IC50=10 μM).		c-Met/HGFR , Antibacterial , Antibiotic