cell-membrane — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T21164	Sulfentrazone	FP-846	Others
	Sulfentrazone (FP-846) is purified form of sulfentrazone which acts as a protoporphyrinogen oxidase inhibitor.It is a phenyl triazolinone herbicide		Others
T8851	I3MT-3	HMPSNE	Hippo pathway
	I3MT-3 (HMPSNE) (HMPSNE) is a potent, selective and cell membrane permeability inhibitor of 3-mercaptopyruvate sulfur transferase (3MST), which targets the persulfated cysteine residues located at the active site of 3MST...		Hippo pathway
T10952	Dabuzalgron	Ro 115-1240	Apoptosis , Adrenergic Receptor
	Dabuzalgron (Ro 115-1240) is an orally active selective alpha-1A adrenergic receptor agonist used to treat urinary incontinence. Dabuzaron prevents cardiotoxicity caused by doxorubicin by maintaining mitochondrial functi...		Apoptosis , Adrenergic Receptor
T5827	BI-6C9		Apoptosis , Others , Mitochondrial Metabolism
	BI-6C9 is an inhibitor of tBid (Kd = 20 µM).BI-6c9 prevented MOMP and mitochondrial fission, and protected the cells from cell death.		Apoptosis , Others , Mitochondrial Metabolism
T1000L	Chlorhexidine diacetate	Hibitane diacetate,Chlorhexidine Acetate,Bactigras	CAT , Antibacterial , Antibiotic , Antifection
	Chlorhexidine diacetate (Bactigras) is a disinfectant and topical anti-infective agent used also as mouthwash to prevent oral plaque.		CAT , Antibacterial , Antibiotic , Antifection
T6658	SB-408124		OX Receptor
	SB408124 is a non-peptide antagonist for OX1 receptor with Ki of 57 nM and 27 nM in both whole cell and membrane, respectively, exhibits 50-fold selectivity over OX2 receptor.		OX Receptor
T4893	Spermidine	N-(3-Aminopropyl)-1,4-diaminobutane,N-(4-Aminobutyl)-1,3-diaminopropane	Endogenous Metabolite
	Spermidine (N-(3-Aminopropyl)-1,4-diaminobutane) inhibits NOS1 (nNOS). Spermidine binds and precipitates DNA and may be used for purification of DNA binding proteins. Spermidine activates PNK (polynucleotide kinase T4). ...		Endogenous Metabolite
T5080	Spermidine trihydrochloride	Spermidine hydrochloride,4-Azaoctamethylenediamine trihydrochloride	NMDAR , Autophagy
	Spermidine trihydrochloride (4-Azaoctamethylenediamine trihydrochloride), a natural polyamine, is a novel autophagy inducer and negatively modulates N-methyl-d-aspartate (NMDA).		NMDAR , Autophagy
T20843	Aplodan	Nergize,Creatinolfosfate,creatinol-O-phosphate,Creatinolfosfate, Creatinol Phosphate	Others
	Aplodan (creatinol-O-phosphate) exhibits antiischemic and antiarrhythmic capacity and protective action on the cell membrane. Aplodan can be used in research on the ischemic heart or ischemic heart disease with persisten...		Others
T5239	Cholesteryl sulfate sodium	Cholesterol 3-Sulfate Sodium Salt,Sodium Cholesteryl Sulfate	Endogenous Metabolite , PKC
	Cholesteryl sulfate sodium (Sodium Cholesteryl Sulfate) is a sterol sulfate in human plasma. Cholesteryl sulfate sodium is a component of cell membrane and has a regulatory function. Cholesteryl sulfate sodium also activ...		Endogenous Metabolite , PKC
T0386L	Ropivacaine	LEA-103 HCl	Potassium Channel , Sodium Channel
	Ropivacaine (LEA-103 HCl) is a local anaesthetic drug belonging to the amino amide group.		Potassium Channel , Sodium Channel
T6063	LY-411575	LY411575	Apoptosis , Gamma-secretase
	LY-411575, a potent γ-secretase inhibitor, is with IC50 of 0.078 nM in the membrane and 0.082 nM in cell-based. It also suppresses Notch clevage with IC50 of 0.39 nM.		Apoptosis , Gamma-secretase
TF0083	POPE
	POPE is a compound found in Escherichia coli, part of the cell membrane, and can be used to study changes in cell membrane permeability.
T1497	Liranaftate	Piritetrate,M-732	Antifungal
	Liranaftate (Piritetrate) is a thiocarbamate and squalene epoxidase inhibitor with antifungal activity. Liranaftate inhibits fungal squalene epoxidase, an enzyme that plays a key role in the synthesis of sterol which is ...		Antifungal
T1290	Oxiconazole nitrate	Ro 13-8996	Others , Antibiotic , Antifection , Antifungal
	Oxiconazole nitrate (Ro 13-8996) is the nitrate salt form of oxiconazole, a broad spectrum imidazole derivative with antifungal activity. Although the exact mechanism of action has yet to be fully elucidated, oxiconazole...		Others , Antibiotic , Antifection , Antifungal
T1187	Bifonazole	Bay H-4502	P450 , Antibiotic , Antifungal
	Bifonazole (Bay H-4502) acts to destabilize the fungal cytochrome p450 51 enzyme (also known as Lanosterol 14-alpha-demethylase). It works by inhibiting the production of a substance called ergosterol, which is an essent...		P450 , Antibiotic , Antifungal
T3934	Isavuconazonium sulfate		Antifungal
	Isavuconazonium sulfate is hydrolyzed by plasma esterases to yield the active moiety isavuconazole. Isavuconazole binds to and inhibits the fungal cytochrome P450 family enzyme lanosterol 14-alpha-demethylase (CYP51), wh...		Antifungal
T6645	Ropivacaine hydrochloride monohydrate	Ropivacaine HCl,Ropivacaine HCl monohydrate,LEA 103,LEA-103 HCl	Potassium Channel , Sodium Channel
	Ropivacaine hydrochloride monohydrate (LEA-103 HCl) is an anaesthetic agent and blocks impulse conduction in nerve fibres through inhibiting sodium ion influx reversibly.		Potassium Channel , Sodium Channel
T20642	Laurdan	6-Dodecanoyl-2-dimethylaminonaphthalene	Others
	Laurdan (6-Dodecanoyl-2-dimethylaminonaphthalene) is a fluorescent membrane probe that is spectrally sensitive to the phospholipid phase of the cell membrane to which it binds.		Others
T6686	Sulconazole mononitrate	Exelderm,Sulconazole Nitrate,RS 44872	Antibacterial , Antibiotic , Antifungal
	Sulconazole mononitrate (Exelderm) is the nitrate salt form of sulconazole, a synthetic imidazole derivative with the antifungal property. Sulconazole mononitrate inhibits fungal cytochrome P-450 sterol C-14 alpha-demeth...		Antibacterial , Antibiotic , Antifungal