carcinogenesis — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T2982	Xanthone	Genicide,Xanthenone,Benzophenone oxide	Apoptosis , Others , Influenza Virus , Antibacterial , Antifungal
	Xanthone (Xanthenone) is currently used as ovicide for codling moth eggs and as a larvicide.
T5799	Arecaidine hydrochloride		Others
	Arecaidine hydrochloride may have carcinogenesis.		Others
T7871	Calcium D-saccharate tetrahydrate	D-Glucaric acid calcium salt,Calcium D-saccharate tetrahydrate,D-Saccharic acid calcium salt	Others
	Calcium D-saccharate tetrahydrate (Calcium D-saccharate tetrahydrate) is an oxidized non-cyclic hexose sugar. It may inhibit carcinogenesis and proliferation of cancer cells.		Others
T22218	2'-Deoxyguanosine	Deoxyguanosine,Guanine deoxyriboside	Endogenous Metabolite
	2'-Deoxyguanosine (Guanine deoxyriboside) is a purine nucleoside that is recognized by members of the 2'-dG-II family.2'-Deoxyguanosine has been associated with aging, mutation, and carcinogenesis, and is oxidized by mol...		Endogenous Metabolite
T77555	3-Methoxycatechol	1,2-Dihydroxy-3-methoxybenzene	Antiviral
	3-Methoxycatechol is a lignin-derived renewable chemical that promotes carcinogenesis in the esophagus.1,2-Dihydroxy-3-methoxybenzen exhibits strong antiviral activity against encephalomyelitis virus (EMCV).		Antiviral
T2737	Neohesperidin	Hesperetin 7-O-neohesperidoside,NSC 31048	Antioxidant
	Neohesperidin (NSC-31048) with antioxidant and neuroprotective properties. Unlike other citrus flavanones, it does not inhibit oral carcinogenesis in a rat model.		Antioxidant
T4863	DL-Homocysteine	2-Amino-4-mercaptobutyric acid	Endogenous Metabolite
	DL-Homocysteine (2-Amino-4-mercaptobutyric acid) is a potential marker for tumor cell growth. increased plasma homocysteine is a risk factor for coronary heart disease and carcinogenesis.		Endogenous Metabolite
TN2258	Tartrazine	FD&C Yellow No. 5,Acid Yellow 23	Others
	Tartrazine (Acid Yellow 23) is a food additive that belongs to a class of artificial dyes and contains an azo group; it has significant genotoxic effect , may be harmful to health and its prolonged use could trigger carc...		Others
T21686	CD 1530	CD-1530,CD1530	Retinoid Receptor
	CD 1530 is a selective and potent RARγ agonist (Kd:150 nM) with potential anticancer activity, shows insecticidal activity against Cryptobacterium hidradii nematodes, and can be used to study oral carcinogenesis.		Retinoid Receptor
T5497	AMAROGENTIN		Apoptosis , AMPK
	Amarogentin is mainly extracted from Swertia and Gentiana roots. It plays cemopreventive/therapeutic role during liver carcinogenesis through modulation of cell cycle and apoptosis		Apoptosis , AMPK
TN1244	3'-Demethylnobiletin		LDL , NF-κB , Integrin , Lipoxygenase , DNA/RNA Synthesis
	3'-Demethylnobiletin has chemopreventive effects on colon carcinogenesis, it can significantly inhibit the growth of human colon cancer cells, cause cell-cycle arrest, induce apoptosis, and profoundly modulate signaling ...		LDL , NF-κB , Integrin , Lipoxygenase , DNA/RNA Synthesis
TN2330	Phenethyl ferulate	Caffeic Acid 3-Methyl Phenethyl Ester	Lipoxygenase , COX
	Phenethyl ferulate (Caffeic Acid 3-Methyl Phenethyl Ester) has chemopreventive properties against chemically induced colon carcinogenesis. It enhances apoptosis in azoxymethane induced colon tumors. It shows inhibitory a...		Lipoxygenase , COX
TN1088	3,5,6,7,8,3',4'-Heptemthoxyflavone	3,3',4',5,6,7,8-heptamethoxyflavone	Others
	3,5,6,7,8,3',4'-Heptemthoxyflavone has neuroprotective, chemopreventive, anti-allergic, anti-inflammatory, immunomodulatory, anti-aging and photoprotective effects; it inhibits collagenase activity and induces type I pro...		Others
T4115	Auraptene	7-geranyloxycoumarin	MMP , BACE
	Auraptene is a coumarin derived from citrus plants that bears a geranyloxyl moiety at its C-7. It has anti-inflammatory, anti-carcinogenic, anti-bacterial, neuroprotective, and hepatoprotective activities. It inhibits le...		MMP , BACE
TN1712	Gossypin		NF-κB , S6 Kinase
	Gossypin has antidiabetic, antioxdiant, anticonvulsant, anti-allergic, antiinflammatory, antinociceptive, cytotoxic and antibacterial activities; it inhibits the NF-kappaB activation pathway, which may explain its role i...		NF-κB , S6 Kinase
T7190	Actein		Apoptosis , Akt , JNK , Autophagy
	Actein has a stimulatory effect on osteoblastic bone formation or has potential activity against osteoporosis, it also can prevent oxidative damage to osteoblasts in osteoporotic patients. Actein's ability to pathways in...		Apoptosis , Akt , JNK , Autophagy
T4971	5'-DEOXYADENOSINE	5′-dAdo	Endogenous Metabolite
	5'-Deoxyadenosine (5′-dAdo) is an oxidized nucleoside found in the urine of normal subjects. Oxidized nucleosides represent excellent biomarkers for determining the extent of damage in genetic material, which has long be...		Endogenous Metabolite
T3S0013	Ethyl trans-caffeate	Ethyl caffeate,Caffeic Acid Ethyl Ester	Others
	1. Ethyl trans-caffeate (Caffeic Acid Ethyl Ester) has anti-inflammatory activity. 2. Ethyl trans-caffeate may as a promising natural compound for future application in chronic liver disease. 3. Ethyl trans-caffeate is a...		Others
T36696	DMBA
	7,12-Dimethylbenz[a]anthracene (DMBA) is a polycyclic aromatic hydrocarbon (PAH) that has been found in tobacco smoke and diesel exhaust and has carcinogenic activity.1,2It undergoes metabolic activation by numerous enzy...
T19189	Allocholic acid		Others
	Allocholic acid is a fetal bile acid found in vertebrates and reappears during liver regeneration and carcinogenesis. It is also a potent and specific stimulant of the adult olfactory system.		Others