behavioral — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T4007	Eticlopride hydrochloride		Dopamine Receptor
	Eticlopride, an antipsychotic, is a Selective dopamine D2/D3 receptor antagonist (Ki: 0.5/0.16 nM).		Dopamine Receptor
T10603	BRD-6929		HIV Protease , HDAC
	BRD-6929 is a selective, brain-penetrant HDAC1 and HDAC2 inhibitor (IC50: 1 and 8 nM). BRD-6929 (Cpd-60) shows high-affinity to HDAC1 and HDAC2 (Kis: 0.2 and 1.5 nM) [2]. BRD-6929 potentiates the efficacy of gnidimacrin...		HIV Protease , HDAC
T21635	PD184161		MEK
	PD184161 is a novel, orally-active MEK inhibitor. PD184161 inhibited MEK activity (IC50 = 10-100 nM) in a time- and concentration-dependent manner[1].		MEK
T27186	Divaplon	RU-32698,RU32698,RU 32698	GABA Receptor
	Divaplon is a GABA receptor agonist (IC50: 0.056 µM) that displays non-sedating anxiolytic behavioral characteristics in a rat model of anxiety.		GABA Receptor
TP1578L	Neuropeptide EI, rat acetate	Neuropeptide EI, rat acetate(125934-45-4 free base)	Melanocortin Receptor , Melanin-concentrating Hormone Receptor (MCHR)
	Neuropeptide EI, rat acetate Displays functional MCH-antagonist and MSH-agonist activity in different behavioral paradigms.
T68080	Gevotroline		5-HT Receptor
	Gevotroline, a chemical in palm wine that can be used to treat psychosis, is a 5-HT2 receptor antagonist that can be used to study behavioral disorders.		5-HT Receptor
T0632	3,4,5-Trimethoxybenzoic acid	Gallic acid trimethyl ether,Eudesmic acid,Trimethylgallic Acid,Benzoic acid,Tri-O-methylgallic acid	Antioxidant
	3,4,5-Trimethoxybenzoic acid (Gallic acid trimethyl ether) are potent antioxidants and inhibitor of cytokine production. It can ameliorate chronic stress-induced various behavioral and biochemical alterations in mice. It...		Antioxidant
T79909	AEF0117		Cannabinoid Receptor
	AEF0117, a signaling-specific inhibitor of cannabinoid receptor 1 (CB1-SSi), inhibits cannabinoid self-administration and behavioral disorders associated with THC, and can be used to study cannabis withdrawal.		Cannabinoid Receptor
T27806	Lecozotan HCl	SRA-333,SRA333,SRA 333,Lecozotan hydrochloride	5-HT Receptor
	Lecozotan HCl (SRA-333) is a potent and selective 5-HT antagonist that significantly enhances KCl-stimulated glutamate and acetylcholine release from the hippocampal dentate gyrus and has cognitive enhancing properties. ...		5-HT Receptor
T33816	Ordopidine	ACR-325,ACR 325,ACR325	Dopamine Receptor
	Ordopidine (ACR325) is a dopaminergic stabilizer that suppresses psychostimulant-induced hyperactivity disorder and stimulates behavior during inactivity. Ordopidine acts as a dopamine D2 receptor antagonist in vitro and...		Dopamine Receptor
T10142L	P-Ethynylphenylalanine hydrochloride	4-Ethynyl-L-phenylalanine HCL,p-Ethynylphenylalanine hydrochloride(278605-15-5 free base)	Hydroxylase
	p-Ethynylphenylalanine hydrochloride (4-Ethynyl-L-phenylalanine HCL) is a novel, potent and specific inhibitor of TPH[1]. The potential for p-Ethynylphenylalanine hydrochloride to inhibit selectively and reversibly the b...		Hydroxylase
T4S1999	Valepotriate	Valtrate	Apoptosis , HIV Protease
	Valepotriate (Valtrate) fraction can have sedative effects and affect behavioral parameters related to recognition memory. Valepotriates, a new class of cytotoxic and antitumor agents, they are very potent cytotoxic agen...		Apoptosis , HIV Protease
T5S0661	Koumine		Others
	1. Koumine can treat the diabetic neuropathy. 2. Koumine has antineoplastic effect, may be a future breast cancer chemotherapeutic agent. 3. Koumine has a significant analgesic effect in rodent behavioral models of infla...		Others
T68070	Fezolamine		Norepinephrine
	Fezolamine is a novel orally available non-tricyclic compound with antidepressant activity. It is three to two times more selective in blocking synaptosomal uptake of [3H]norepinephrine than uptake of [4H]3-hydroxytrypta...		Norepinephrine
T22043	BCATc Inhibitor 2		Others
	BCATc Inhibitor 2 exhibited an IC50 of 0.8 microM in the hBCATc assays; it is an active and selective inhibitor. BCATc Inhibitor 2 also blocked calcium influx into neuronal cells following inhibition of glutamate uptake,...		Others
T4S0969	Obtusifolin		Antioxidant , NF-κB
	1. Obtusifolin has antioxidant properties and improves chemically induced diabetes and its complications by modulation of oxidative stress. 2. Obtusifolin suppresses phthalate esters-mediated bone resorption, thus may be...		Antioxidant , NF-κB
T28634	RY024
	RY024 is a behavioral alcohol antagonist.
T27857	LSP4-2022	LSP42022,LSP4 2022
	LSP4-2022, a mGlu4 selective agonist, increases behavioral despair in mouse models of antidepressant action.
T33696	NK-1145	NK-1145 hydrocholdoride,NK 1145,NK1145
	Nk-1145 is a parasympathetic drug of the autonomic nervous system, which can cause behavioral stimulation and excitement.
T20821	EPPS
	EPPS is a rescuer of A aggregation and behavioral deficits. It binds to A aggregates and converts them into monomers.