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Eticlopride hydrochloride

Catalog No. T4007 CAS 97612-24-3

Eticlopride, an antipsychotic, is a Selective dopamine D2/D3 receptor antagonist (Ki: 0.5/0.16 nM).

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Eticlopride hydrochloride, CAS 97612-24-3

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Eticlopride, an antipsychotic, is a Selective dopamine D2/D3 receptor antagonist (Ki: 0.5/0.16 nM).
Targets&IC50	D3:0.16 nM, D2:0.50 nM

Molecular Weight	377.31
Formula	C17H25ClN2O3.HCl
CAS No.	97612-24-3

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

H2O: 30 mg/mL

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Hall H, et al. Some in vitro receptor binding properties of [3H]eticlopride, a novel substituted benzamide, selective for dopamine-D2 receptors in the rat brain[J]. European Journal of Pharmacology, 1985, 111(2):191-199. 2. Giuliani D, Ferrari F. Involvement of dopamine receptors in the antipsychotic profile of (-) eticlopride[J]. Physiology & Behavior, 1997, 61(4):563.

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Eticlopride hydrochloride 97612-24-3 GPCR/G Protein Neuroscience Dopamine Receptor Eticlopride Extrapyramidal side effects Dopamine D2‐like receptors inhibit Inhibitor Behavioral pharmacology inhibitor

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