20
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T60022 | Aromatase-IN-2 | Others | |
Aromatase-IN-2 has anti-inflammatory, antitumor and antiasthmatic effects. | |||
T60006 | Aromatase inhibitor 23 | Others | |
Aromatase inhibitor 23 is an inhibitor that target protein-protein interactions in RAD51 family of recombinases. | |||
T61444 | Nonsteroidal aromatase inhibitor 1 | ||
Nonsteroidal aromatase inhibitor 1 (Compound 13h) effectively inhibits the enzyme CYP19A1 with an IC50 value of 0.09 nM. Due to its potent inhibitory activity, Nonsteroidal aromatase inhibitor 1 holds promise for researc... | |||
T61463 | Monoamine oxidase/Aromatase-IN-1 | ||
Monoamine oxidase/Aromatase-IN-1 (compound 2q) is a potent dual inhibitor of monoamine oxidase (MAO) and aromatase, with IC50 values of 39 nM and 31 nM for MAO-B and aromatase, respectively. It holds significant potentia... | |||
T7197 | Fadrozole | Aromatase | |
Fadrozole is a nonsteroidal aromatase inhibitor with potential antineoplastic activity(IC50 : 6.4 nM) | |||
T7999 | 7-Hydroxyflavanone | Anti-infection | |
7-Hydroxyflavanone shows antimicrobial activity against Streptococcus pneumoniae clinical isolates. | |||
T11991 | Mefentrifluconazole | P450 , Antifungal | |
Mefentrifluconazole is a potent, selective and orally active fungal CYP51 (Kd= 0.5 nM) inhibitor, but shows less inhibitory activity on human aromatase (IC50=0.92 μM). Mefentrifluconazole is a novel azole derivative and ... | |||
T0393 | Anastrozole | ZD1033 | Aromatase |
Anastrozole (ZD1033)(ZD1033), a potent and highly selective aromatase (CYP19) inhibitor (IC50 = 15 nM), has no obvious effect on adrenocorticoid hormone synthesis. | |||
T1590 | Letrozole | CGS 20267 | Aromatase , Autophagy |
Letrozole (CGS 20267) is an Aromatase Inhibitor. The mechanism of action of letrozole is as an Aromatase Inhibitor. | |||
T7556 | Fadrozole hydrochloride | CGS 16949A | Aromatase |
Fadrozole hydrochloride (CGS 16949A) is a model aromatase inhibitor that has been shown to suppress estrogen production in the ovaries of fish. | |||
T1103 | Aminoglutethimide | DL-Aminoglutethimide,BA-16038,NSC-330915 | Aromatase |
Aminoglutethimide (BA-16038), an aromatase inhibitor, is used in the therapy of advanced BREAST Y. | |||
T6917 | Oleuropein | Apoptosis , Aromatase , ROS , PPAR | |
Oleuropein is an antioxidant polyphenol isolated from olive leaf. | |||
T2O2744 | Alpha-Naphthoflavone | 7,8-benzoflavone | Aromatase |
alpha-Naphthoflavone (7,8-benzoflavone), a synthetic flavonoid, is a potent inhibitor of aromatase with an I50 value of 0.5 μM. | |||
T20625 | Prochloraz | Sporgon,Prelude | Estrogen Receptor/ERR , AhR , Androgen Receptor , Antifungal |
Prochloraz (Prelude) is a broad-spectrum contact imidazole fungicide. Prochloraz inhibits human placental microsomal aromatase in vitro (IC50 = 40 nM). Prochloraz also acts as an estrogen receptor (IC50s = 25 μM) and and... | |||
T1587 | Exemestane | EXE,FCE 24304,PNU155971 | Aromatase |
Exemestane (EXE) is an Aromatase Inhibitor. The mechanism of action of exemestane is as an Aromatase Inhibitor. | |||
T0530 | Flavanone | 2-Phenyl-4-chromanone,4-Flavanone,2,3-Dihydroflavone,2-Phenylchroman-4-one | Others , Aromatase |
Flavanone (2-Phenylchroman-4-one)s from citrus fruits have also been shown to exert beneficial effects on human vascular function. In particular, chronic interventions with orange juice, or the pure flavanone hesperidin,... | |||
TN3987 | Eriodictyol chalcone | Anti-infection , Aromatase | |
Eriodictyol chalcone has anti-plasmodial effects on P. falciparum growth. | |||
T4281 | Endoxifen | (E/Z)-N-desmethyl-4-hydroxy Tamoxifen,(E/Z)-Endoxifen | Estrogen Receptor/ERR , Aromatase , Estrogen/progestogen Receptor , Parasite , Drug Metabolite |
(E/Z)-Endoxifen ((E/Z)-Endoxifen) is an active metabolite of tamoxifen produced by the sequential action of cytochrome P450 (CYP) isoforms, including CYP2D6. It is a strong anti-estrogen, as it has an approximately 100-f... | |||
T71708 | Minamestane | Aromatase | |
Minamestane is a novel irreversible aromatase inhibitor.Minamestane induces time-dependent inhibition of human placental aromatase with a half-life of 4 minutes and a K of 59 nM.Minamestane has antitumor activity. | |||
T27320 | Finrozole | MPV 2213ad,MPV-2213ad,MPV 2213,MPV-2213,MPV2213ad | Aromatase |
Finrozole (MPV 2213ad) is a novel selective aromatase inhibitor that is partially reversible for breast development. |