Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Anastrozole (ZD1033)(ZD1033), a potent and highly selective aromatase (CYP19) inhibitor (IC50 = 15 nM), has no obvious effect on adrenocorticoid hormone synthesis.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
10 mg | In stock | $ 45.00 | |
25 mg | In stock | $ 61.00 | |
50 mg | In stock | $ 77.00 | |
100 mg | In stock | $ 117.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 48.00 |
Description | Anastrozole (ZD1033)(ZD1033), a potent and highly selective aromatase (CYP19) inhibitor (IC50 = 15 nM), has no obvious effect on adrenocorticoid hormone synthesis. |
Targets&IC50 | Aromatase:15 nM |
Kinase Assay | Aromatase inhibition is measured using human placental microsomes and the method of Thompson and Siiteri with Testosterone (0.5 μM) as substrate. 11-hydroxylase inhibition is determined by measuring the conversion of [1,2,6,7-3H]-ll-deoxy- cortisol to cortisol using freshly prepared mitochondria from guinea pig, dog and cow adrenal glands. Reaction products are extracted into chloroform and separated by thin layer chromatography[1]. |
Synonyms | ZD1033 |
Molecular Weight | 293.37 |
Formula | C17H19N5 |
CAS No. | 120511-73-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 29.3 mg/mL (100 mM)
Ethanol: 29.3 mg/mL (100 mM)
You can also refer to dose conversion for different animals. More
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Anastrozole 120511-73-1 Endocrinology/Hormones Aromatase Inhibitor ZD 1033 ZD-1033 inhibit ZD1033 inhibitor