antiretroviral — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T11465	Lenacapavir	GS-6207	Others , HIV Protease
	Lenacapavir (GS-6207) is a potent capsid-targeting inhibitor of HIV replication. Lenacapavir shows anti-HIV activity with an EC50 of 100 pM in MT-4 cells.		Others , HIV Protease
T2578	Didanosine	ddI,2',3'-Dideoxyinosine	HIV Protease , Reverse Transcriptase
	Didanosine (ddI) is a nucleoside reverse transcriptase inhibitor analog of adenosine (IC50: 0.49 μM).		HIV Protease , Reverse Transcriptase
T19963	Alizarin Complexone	Alizarin Fluorine Blue,Alizarin-3-methyliminodiacetic acid	Reverse Transcriptase
	Alizarin Complexone (Alizarin-3-methyliminodiacetic acid) is an inhibitor of Rous-associated virus 2 reverse transcriptase. Alizarin Complexone can be used as a calcium-tracer and a chelating agent for biological studies...		Reverse Transcriptase
T6098	Cabotegravir	GSK744,GSK-1265744,S/GSK1265744	HIV Protease
	Cabotegravir (S/GSK1265744) (GSK744, GSK1265744) is a long-acting HIV integrase inhibitor and inhibits the HIV-1 integrase catalyzed strand transfer reaction (IC50: 3.0 nM).		HIV Protease
T1404	Stavudine	d4T,Sanilvudine,BMY-27857,NSC 163661	Apoptosis , Nucleoside Antimetabolite/Analog , HIV Protease , NOD-like Receptor (NLR) , Reverse Transcriptase , Autophagy
	Stavudine (BMY-27857), a nucleoside reverse transcriptase inhibitor analog of thymidine, has activity against HIV.
T4326	AG 555	Tyrphostin B46,Tyrphostin AG 555	EGFR , Reverse Transcriptase
	AG 555 (Tyrphostin B46) is an EGFR tyrosine kinase inhibitor.		EGFR , Reverse Transcriptase
T27154	Dexelvucitabine	D-D-4FC,DPC-817,RVT,beta-D-D-4FC,DFC	Reverse Transcriptase
	Dexelvucitabine (RVT), a nucleoside reverse transcriptase inhibitor, is used potentially for the treatment of HIV infection.		Reverse Transcriptase
T8238	Fosamprenavir Calcium Salt	Diallyl Trisulfide,GW433908G	HIV Protease
	Fosamprenavir Calcium Salt (GW433908G) (GW433908G) is a phosphate ester prodrug of the antiretroviral protease inhibitor Amprenavir, with improved solubility. Fosamprenavir Calcium Salt has Anti-HIV infection.		HIV Protease
T30047	Ancriviroc	Schering C,SCH-351125,[3H]ancriviroc,CHEMBL336672,AC1NUILE	HIV Protease
	Ancriviroc(CHEMBL336672), an imidoxime with strong antiretroviral activity, is a potent CCR5 inhibitor that can be used to study HIV.		HIV Protease
T7903	Saquinavir	Ro 31-8959	SARS-CoV , HIV Protease
	Saquinavir (Ro 31-8959) is a potent HIV protease inhibitor, is an antiretroviral drug used together with other medications to treat or prevent HIV/AIDS.		SARS-CoV , HIV Protease
T5949	Dideoxyadenosine
	2',3'-Dideoxyadenosine is an inhibitor of HIV replication with antiretroviral activity and antiviral efficacy [1].
T14313	Apricitabine	AVX754,SPD754	HIV Protease , DNA/RNA Synthesis
	Apricitabine (SPD754) is a highly selective and orally active HIV-1 reverse transcriptase inhibitor (Ki=0.08 μM), the (-) enantiomer of 2′-deoxy-3′-oxy-4′-thiocytidine (dOTC) . Apricitabine inhibits DNA polymerase α, β a...		HIV Protease , DNA/RNA Synthesis
T2409	Tenofovir alafenamide	GS-7340	HIV Protease , Reverse Transcriptase
	Tenofovir alafenamide (GS-7340) is a nucleotide reverse transcriptase inhibitor (NRTI) and a novel ester prodrug of the antiretroviral tenofovir.		HIV Protease , Reverse Transcriptase
T7779	Nelfinavir	AG1341	HIV Protease
	Nelfinavir (AG1341) is an antiretroviral drug used in the treatment of the human immunodeficiency virus (HIV) (Ki=2 nM). Nelfinavir is a broad-spectrum, anticancer agent.		HIV Protease
T1595	Nevirapine	NSC 641530,BI-RG 587,NVP	HIV Protease , Reverse Transcriptase
	Nevirapine (NVP) is a benzodiazepine non-nucleoside reverse transcriptase inhibitor. In combination with other antiretroviral drugs, nevirapine reduces HIV viral loads and increases CD4 counts, thereby retarding or preve...		HIV Protease , Reverse Transcriptase
T2830	Betulinic acid	ALS-357,Lupatic acid,Betulic acid	Apoptosis , Mitophagy , NF-κB , HIV Protease , Topoisomerase , Endogenous Metabolite , Aminopeptidase , Autophagy
	Betulinic acid (ALS-357) is a pentacyclic lupane-type triterpene derivative of betulin (isolated from the bark of Betula alba, the common white birch) which has antiretroviral, antimalarial, and anti-inflammatory propert...
T11538	Hck-IN-1		HIV Protease , Src , Hck
	Hck-IN-1 is a selective Nef-dependent Hck inhibitor (IC50s: 2.8 μM and >20 μM for Nef:Hck complex and Hck) with antiretroviral activity. Hck-IN-1 is a direct and wide HIV-1 Nef antagonist with an IC50 of 100-300 nM for w...		HIV Protease , Src , Hck
T80644	DNA polymerase-IN-1		Antiviral , DNA/RNA Synthesis
	DNA polymerase-IN-1, a DNA polymerase inhibitor, exhibited antiproliferative activity against tumor cells with a half-inhibitory concentration (IC50) of 20.7 μM. DNA polymerase-IN-1 inhibited Taq DNA polymerase with an I...		Antiviral , DNA/RNA Synthesis
T28946	Tenofovir exalidex	Tenofovir,HDP-Tenofovir,CMX-157,CMX157,CMX 157	Antiviral
	Tenofovir exalidex (CMX 157) is a lipid-conjugated acyclic nucleotide analog of Tenofovir, demonstrating efficacy against wild-type and antiretroviral-resistant HIV strains, including those resistant to multiple nucleosi...		Antiviral
T68666	Benfluron Hydrochloride
	Benfluron Hydrochloride is an inhibitor of HIV-1 Rev function which also acts as a cytostatic agent with substantial antiretroviral activity.