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Nelfinavir

Name: Nelfinavir
Brand: TargetMol
SKU: T7779
Price: 540 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T7779Cas No. 159989-64-7

Alias AG1341

Nelfinavir (AG1341) is an antiretroviral drug used in the treatment of the human immunodeficiency virus (HIV) (Ki=2 nM). Nelfinavir is a broad-spectrum, anticancer agent.

Nelfinavir

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Purity: 99.5%

Catalog No. T7779Alias AG1341Cas No. 159989-64-7

Nelfinavir (AG1341) is an antiretroviral drug used in the treatment of the human immunodeficiency virus (HIV) (Ki=2 nM). Nelfinavir is a broad-spectrum, anticancer agent.

Pack Size	Price	Availability
1 mg	$51	In Stock
5 mg	$154	In Stock
10 mg	$232	In Stock
25 mg	$387	In Stock
50 mg	$540	In Stock
100 mg	Inquiry	In Stock
1 mL x 10 mM (in DMSO)	$186	In Stock

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Purity:99.5%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	Nelfinavir (AG1341) is an antiretroviral drug used in the treatment of the human immunodeficiency virus (HIV) (Ki=2 nM). Nelfinavir is a broad-spectrum, anticancer agent.
Targets&IC50	HIV:2 nM (ki)
In vitro	Nelfinavir decreased the viability of a panel of drug-resistant breast cancer cell lines and inhibited the growth of NSCLC xenografts that was associated with induction of ER stress, autophagy, and apoptosis. Nelfinavir is a lead HIV protease inhibitor with pleiotropic effects in cancer cells[1]
Synonyms	AG1341

Chemical Properties

Molecular Weight	567.78
Formula	C₃₂H₄₅N₃O₄S
Cas No.	159989-64-7
Smiles	Cc1c(O)cccc1C(=O)N[C@@H](CSc1ccccc1)[C@H](O)CN1C[C@H]2CCCC[C@H]2C[C@H]1C(=O)NC(C)(C)C
Relative Density.	1.22g/cm3
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 100 mg/mL (176.12 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 4 mg/mL (7.04 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.7612 mL	8.8062 mL	17.6125 mL	88.0623 mL
5 mM	0.3522 mL	1.7612 mL	3.5225 mL	17.6125 mL
10 mM	0.1761 mL	0.8806 mL	1.7612 mL	8.8062 mL
20 mM	0.0881 mL	0.4403 mL	0.8806 mL	4.4031 mL
50 mM	0.0352 mL	0.1761 mL	0.3522 mL	1.7612 mL
100 mM	0.0176 mL	0.0881 mL	0.1761 mL	0.8806 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc