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Alizarin Complexone

Catalog No. T19963 CAS 3952-78-1

Synonyms: Alizarin-3-methyliminodiacetic acid, Alizarin Fluorine Blue

Alizarin Complexone is an inhibitor of Rous-associated virus 2 Reverse Transcriptase. Alizarin Complexone can be used as a calcium-tracer and a chelating agent for biological studies.

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Alizarin Complexone, CAS 3952-78-1

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Alizarin Complexone is an inhibitor of Rous-associated virus 2 reverse transcriptase. Alizarin Complexone can be used as a calcium-tracer and a chelating agent for biological studies.

Synonyms	Alizarin-3-methyliminodiacetic acid, Alizarin Fluorine Blue
Molecular Weight	385.32
Formula	C19H15NO8
CAS No.	3952-78-1

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

DMSO: <10mM

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Oshima T, et al. Selective extraction of histidine derivatives by metal affinity with a copper(II)-chelating ligand complex in an aqueous two-phase system. J Chromatogr B Analyt Technol Biomed Life Sci. 2015;990:73-79. 2. Higuchi H, et al. Antiretroviral activities of anthraquinones and their inhibitory effects on reverse transcriptase. Antiviral Res. 1991;15(3):205-216. 3. Zou Z, et al. Alizarin Complexone Functionalized Mesoporous Silica Nanoparticles: A Smart System Integrating Glucose-Responsive Double-Drugs Release and Real-Time Monitoring Capabilities. ACS Appl Mater Interfaces. 2016 Apr 6;8(13):8358-66. 4. Zhao YP, et al. [Use of alizarin red S and alizarin complexone for immersion marking Sinocyclocheilus grahami]. Dongwuxue Yanjiu. 2013 Oct;34(5):499-503. Chinese.

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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The answer of 19.713 mg appears in the Mass box

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What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Alizarin Complexone 3952-78-1 Microbiology/Virology Reverse Transcriptase Inhibitor antiretroviral activities inhibit Alizarin-3-methyliminodiacetic acid RAV-2 calcium tracer a chelating agent Alizarin Fluorine Blue inhibitor

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