Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Nevirapine (NVP) is a benzodiazepine non-nucleoside reverse transcriptase inhibitor. In combination with other antiretroviral drugs, nevirapine reduces HIV viral loads and increases CD4 counts, thereby retarding or preventing the damage to the immune system and reducing the risk of developing AIDS.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | $ 31.00 | |
10 mg | In stock | $ 50.00 | |
50 mg | In stock | $ 59.00 | |
100 mg | In stock | $ 81.00 | |
200 mg | In stock | $ 89.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 50.00 |
Description | Nevirapine (NVP) is a benzodiazepine non-nucleoside reverse transcriptase inhibitor. In combination with other antiretroviral drugs, nevirapine reduces HIV viral loads and increases CD4 counts, thereby retarding or preventing the damage to the immune system and reducing the risk of developing AIDS. |
Targets&IC50 | HIV-1:270 μM(ki) |
Cell Research | FRO cells are seeded into 96-well culture plates at 10,000 cells/well. Cells are treated with different doses of nevirapine (0, 100, 200, 350 and 500 μM) for 48 h. MTT dye (5 mg/mL) is added to each well for additional 4 h, and the reaction is then stopped by the addition of DMSO. Optical density is measured at 490 nm on a multi-well plate reader[2]. |
Synonyms | NSC 641530, BI-RG 587, NVP |
Molecular Weight | 266.3 |
Formula | C15H14N4O |
CAS No. | 129618-40-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ethanol: < 1 mg/mL (insoluble or slightly soluble)
DMSO: 49 mg/mL (184 mM)
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Nevirapine 129618-40-2 Microbiology/Virology Proteases/Proteasome Reverse Transcriptase HIV Protease HIV NSC 641530 BI-RG587 Human immunodeficiency virus inhibit NSC641530 BI-RG 587 Inhibitor NVP BI-RG-587 NSC-641530 inhibitor