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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T82424 | Experimental allergic encephalitogenic peptide (human) | ||
Experimental allergic encephalitogenic peptide (human), an EAE peptide, induces encephalomyelitis in guinea pigs [1]. | |||
T8239 | Cromoglicic acid | Others | |
Cromoglicic acid prevents the release of inflammatory chemicals such as histamine from mast cells. | |||
T4S0398 | Rosin | p38 MAPK | |
Rosin is a natural product,may have therapeutic potential for the treatment of inflammation | |||
T12651 | Rabdosiin | (+)-Rabdosiin | Others |
Rabdosiin ((+)-Rabdosiin) is a natural product, and has anti-allergic activity, anti-HIV activity and inhibition on DNA topoisomerase. | |||
T15598 | Isosulfan blue | Others | |
Isosulfan blue is a blue dye for the identification of lymph vessels during lymphangiography. Isosulfan blue is used during sentinel lymph node biopsies in breast cancer. However, Isosulfan blue may be a cause of allergi... | |||
TN1416 | Ayanin | IL Receptor , P450 , PARP , PDE | |
Ayanin has vasorelaxant activity, it also may have the potential for use in treating allergic asthma.The IC(50) value of Ayanin (quercetin-3,7,4'-O-trimethylether) is 2.2microM for inhibiting interleukin (IL)-4 productio... | |||
T5424 | Etosalamide | Ethosalamide | Others |
Etosalamide (Ethosalamide) is an antipyretic and analgesics agent. | |||
T9926 | Omalizumab | Others | |
Omalizumab is a recombinant humanized monoclonal antibody against human immunoglobulin E IgE) | |||
T4563 | Thonzylamine | neohetramine | Histamine Receptor |
Thonzylamine (neohetramine) is an antihistamine and anticholinergic drug. It is available as combination products with Clofedanol or Phenylephrine for temporary relief of symptoms of common cold, hay fever (allergic rhin... | |||
T4S0878 | Prunetin | Prunusetin | ERK , Dehydrogenase , NF-κB |
1. Prunetin (Prunusetin) significantly reduces serum levels of inflammatory cytokines and mortality in mice challenged with lipopolysaccharide. 2. Prunetin mediates anti-obesity/adipogenesis effects by suppressing obesit... | |||
T9043 | AS1810722 | P450 , STAT | |
AS1810722, a fused bicyclic pyrimidine derivative, is an orally active and potent inhibitor of STAT6, demonstrating an IC50 of 1.9 nM. It exhibits effective inhibition of CYP3A4, positioning it as a promising candidate f... | |||
T7860 | SM-324405 | SM 324405 | TLR |
SM-324405 is an agonist of TLR7. | |||
TN2244 | Sulfuretin | NF-κB , Autophagy | |
Sulfuretin is a potent anti-oxidant, has protective effect against t-BHP-induced oxidative damage in human liver-derived HepG2 cells is attributable to its ability to scavenge ROS and up-regulate the activity of HO-1 thr... | |||
T3979 | Emedastine | LY188695,Emadine | Histamine Receptor |
Emedastine (LY188695) is a second generation, selective histamine H1 receptor antagonist with anti-allergic activity. Emedastine reversibly and competitively blocks histamine by binding to H1 receptors, thus blocking its... | |||
T0211 | Azelastine | Azelastina,Astelin,Azelastinum | SARS-CoV , Histamine Receptor |
Azelastine (Azelastinum) is a phthalazine derivative, and is an histamine antagonist and mast cell stabilizer. | |||
T4348 | Syk Inhibitor II | 5-HT Receptor , Syk | |
Syk inhibitor II, a cell-permeable, ATP-competitive, pyrimidine-carboxamide compound, selectively and reversibly inhibits Syk (IC50 = 41 nM). | |||
T5310 | TR-14035 | MDK-1191 | Integrin |
TR-14035 (MDK-1191) is a dual antagonist of α4β7/α4β1 integrins (IC50s: 7/87nM). | |||
T0118 | Mizolastine | SL 850324 | Histamine Receptor |
Mizolastine (SL 850324) (IC50= 47 nM) is a histamine H1-receptor antagonist.It is used in the treatment of allergic reactions such as hay fever (seasonal allergic rhinitis), hives. | |||
T4038 | Ectoine | THP(B),L-Ectoine | Others , Antibacterial |
Ectoine (L-Ectoine) is an osmoprotectant in a variety of microorganisms including halophilic and heterotrophic bacteria and non-halophilic bacteria such as the Streptomyces species, as well as E.coli. | |||
T6242 | Rupatadine Fumarate | Rinialer,Rupafin,Alergoliber | PAFR , Autophagy , Histamine Receptor |
Rupatadine Fumarate (Rinialer) (UR-12592 Fumarate) is a potent dual PAF/H1 antagonist with Ki of 0.55/0.1 uM. |