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Search Results for " allergic "

20

Compounds

Cat No. Product Name Synonyms Targets
T82424 Experimental allergic encephalitogenic peptide (human)
Experimental allergic encephalitogenic peptide (human), an EAE peptide, induces encephalomyelitis in guinea pigs [1].
T8239 Cromoglicic acid Others
Cromoglicic acid prevents the release of inflammatory chemicals such as histamine from mast cells.
T4S0398 Rosin p38 MAPK
Rosin is a natural product,may have therapeutic potential for the treatment of inflammation
T12651 Rabdosiin (+)-Rabdosiin Others
Rabdosiin ((+)-Rabdosiin) is a natural product, and has anti-allergic activity, anti-HIV activity and inhibition on DNA topoisomerase.
T15598 Isosulfan blue Others
Isosulfan blue is a blue dye for the identification of lymph vessels during lymphangiography. Isosulfan blue is used during sentinel lymph node biopsies in breast cancer. However, Isosulfan blue may be a cause of allergi...
TN1416 Ayanin IL Receptor , P450 , PARP , PDE
Ayanin has vasorelaxant activity, it also may have the potential for use in treating allergic asthma.The IC(50) value of Ayanin (quercetin-3,7,4'-O-trimethylether) is 2.2microM for inhibiting interleukin (IL)-4 productio...
T5424 Etosalamide Ethosalamide Others
Etosalamide (Ethosalamide) is an antipyretic and analgesics agent.
T9926 Omalizumab Others
Omalizumab is a recombinant humanized monoclonal antibody against human immunoglobulin E IgE)
T4563 Thonzylamine neohetramine Histamine Receptor
Thonzylamine (neohetramine) is an antihistamine and anticholinergic drug. It is available as combination products with Clofedanol or Phenylephrine for temporary relief of symptoms of common cold, hay fever (allergic rhin...
T4S0878 Prunetin Prunusetin ERK , Dehydrogenase , NF-κB
1. Prunetin (Prunusetin) significantly reduces serum levels of inflammatory cytokines and mortality in mice challenged with lipopolysaccharide. 2. Prunetin mediates anti-obesity/adipogenesis effects by suppressing obesit...
T9043 AS1810722 P450 , STAT
AS1810722, a fused bicyclic pyrimidine derivative, is an orally active and potent inhibitor of STAT6, demonstrating an IC50 of 1.9 nM. It exhibits effective inhibition of CYP3A4, positioning it as a promising candidate f...
T7860 SM-324405 SM 324405 TLR
SM-324405 is an agonist of TLR7.
TN2244 Sulfuretin NF-κB , Autophagy
Sulfuretin is a potent anti-oxidant, has protective effect against t-BHP-induced oxidative damage in human liver-derived HepG2 cells is attributable to its ability to scavenge ROS and up-regulate the activity of HO-1 thr...
T3979 Emedastine LY188695,Emadine Histamine Receptor
Emedastine (LY188695) is a second generation, selective histamine H1 receptor antagonist with anti-allergic activity. Emedastine reversibly and competitively blocks histamine by binding to H1 receptors, thus blocking its...
T0211 Azelastine Azelastina,Astelin,Azelastinum SARS-CoV , Histamine Receptor
Azelastine (Azelastinum) is a phthalazine derivative, and is an histamine antagonist and mast cell stabilizer.
T4348 Syk Inhibitor II 5-HT Receptor , Syk
Syk inhibitor II, a cell-permeable, ATP-competitive, pyrimidine-carboxamide compound, selectively and reversibly inhibits Syk (IC50 = 41 nM).
T5310 TR-14035 MDK-1191 Integrin
TR-14035 (MDK-1191) is a dual antagonist of α4β7/α4β1 integrins (IC50s: 7/87nM).
T0118 Mizolastine SL 850324 Histamine Receptor
Mizolastine (SL 850324) (IC50= 47 nM) is a histamine H1-receptor antagonist.It is used in the treatment of allergic reactions such as hay fever (seasonal allergic rhinitis), hives.
T4038 Ectoine THP(B),L-Ectoine Others , Antibacterial
Ectoine (L-Ectoine) is an osmoprotectant in a variety of microorganisms including halophilic and heterotrophic bacteria and non-halophilic bacteria such as the Streptomyces species, as well as E.coli.
T6242 Rupatadine Fumarate Rinialer,Rupafin,Alergoliber PAFR , Autophagy , Histamine Receptor
Rupatadine Fumarate (Rinialer) (UR-12592 Fumarate) is a potent dual PAF/H1 antagonist with Ki of 0.55/0.1 uM.
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