xor — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T2397	Topiroxostat	FYX-051	P450 , ROS , Xanthine Oxidase
	Topiroxostat (FYX-051) is a selective xanthine oxidase inhibitor developed for treatment and management of hyperuricemia and gout.		P450 , ROS , Xanthine Oxidase
T15777	Loxoribine	RWJ 21757,7-Allyl-8-oxoguanosine	Influenza Virus , TLR
	Loxoribine (RWJ 21757) is a guanosine analog. Loxoribine is an orally bioavailable and selective Toll-like receptor (TLR) 7 agonist. It has anti-viral and anti-tumor activities.Loxoribine is a potent new immunostimulant ...		Influenza Virus , TLR
T6123	Verdinexor	KPT-335	CRM1
	Verdinexor (KPT-335) (KPT-335), a specific XPO1/CRM1 inhibitor, are orally bioavailable.		CRM1
T3203	Methyl 13-cis-4-Oxoretinoate	13-cis-4-Oxo-retinoic acid Methyl Ester,4-Keto 13-cis-Retinoic Acid Methyl Ester	Others
	Methyl 13-cis-4-Oxoretinoate (13-cis-4-Oxo-retinoic acid Methyl Ester) is a retinoic acid metabolite in neuroblastoma.		Others
T77600	Methyl-4-oxoretinoate		Apoptosis
	Methyl-4-oxoretinoate is a synthetic retinoid compound with anticancer compounds that can induce differentiation and apoptosis in cancer cells.Methyl-4-oxoretinoate is used in the treatment of acne, psoriasis, and other ...		Apoptosis
T6106	Selinexor (KPT-330)	Selinexor,KPT-330	CRM1
	Selinexor (KPT-330) is a small molecule inhibitor of CRM1 with selective and oral activity. Selinexor blocks the cell cycle, induces apoptosis, and has antitumor activity for the treatment of multiple myeloma.		CRM1
T6053	Turofexorate Isopropyl	XL335,FXR-450,WAY-362450	FXR , Autophagy
	Turofexorate Isopropyl (XL335) is a potent, selective, and orally bioavailable FXR agonist with EC50 of 4 nM		FXR , Autophagy
T7436	Cilofexor		FXR , Autophagy
	Cilofexor inhibits binding of a synthetic peptide, Cilofexor is a farnesoid X receptor (FXR) agonist.		FXR , Autophagy
T1020	Doxorubicin hydrochloride	Adriamycin,Doxorubicin (Adriamycin) HCl,Hydroxydaunorubicin hydrochloride,NSC 123127	Apoptosis , Mitophagy , HBV , HIV Protease , Topoisomerase , Antibacterial , Antibiotic , AMPK , Autophagy
	Doxorubicin hydrochloride (Adriamycin) belongs to the anthracycline class of antibiotics and is an inhibitor of human DNA topoisomerase I/II (IC50=0.8/2.67 μM). Doxorubicin hydrochloride exhibits cytotoxicity and antitum...
T11766L	Eltanexor	ONO-7706,KPT-8602,ATG-016	Others
	Eltanexor (ONO-7706) is an orally active exportin-1 (XPO1) inhibitor. It has effective anti-leukemic activity. Eltanexor inhibits XPO1-dependent nuclear export (EC50=60.9 nM) by directly targeting XPO1. Eltanexor causes ...		Others
T11090L1	Aldoxorubicin hydrochloride	Aldoxorubicin hydrochloride (1361644-26-9 Free base）	Topoisomerase
	Aldoxorubicin hydrochloride is an albumin-binding prodrug of Doxorubicin, a DNA topoisomerase II inhibitor. Aldoxorubicin hydrochloride is released from albumin under acidic conditions. Aldoxorubicin hydrochloride exhibi...		Topoisomerase
T7886	Nidufexor		FXR , Autophagy
	Nidufexor is an agonist for the farnesoid X receptor (FXR).		FXR , Autophagy
TP1832	Gluten Exorphin C		Opioid Receptor
	Gluten exorphin C is an opioid peptide derived from wheat gluten. Its IC50 values are 40 μM and 13.5 μM for μ opioid and δ opioid activities in the GPI and MVD assays, respectively.Gluten Exorphin C, isolated from the pe...		Opioid Receptor
T7408	All-trans-4-Oxoretinoic acid	all-trans 4-Keto Retinoic Acid	Endogenous Metabolite
	all-trans-4-Oxoretinoic acid (all-trans 4-Keto Retinoic Acid) is an active metabolite of vitamin A.		Endogenous Metabolite
T4379	Tropifexor	LJN452	FXR , Autophagy
	Tropifexor (LJN452) is a novel and highly potent agonist of FXR with an EC50 of 0.2 nM.		FXR , Autophagy
T8471	Vonafexor	EYP001,PLX007,pxl007	FXR , HBV
	Vonafexor (EYP001) is a farnesoid X receptor (FXR, NR1H4) agonist, with anti-HBV effects		FXR , HBV
T21315	Folitixorin	ANX-510
	ANX-510 is a folate-based biomodulator. It stabilizes the covalent binding of the fluorouracil metabolite FdUMP to thymidylate synthase, which results in inhibition of thymidylate synthase, depletion of thymidine triphos...
T69724	Cilofexor tromethamine
	Cilofexor, also known as GS-9674, is a farnesoid X receptor (FXR) agonist. The nonsteroidal FXR agonist cilofexor (GS-9674) improves markers of cholestasis and liver injury in patients with PSC. In clinical study, cilof...
T25435	Folitixorin calcium	CoFactor,ANX 510,ANX-510,ANX510
	Folitixorin calcium is an antineoplastic enhancing agent.
T70775	Zoptarelin doxorubicin
	Zoptarelin doxorubicin, also known as AEZS-108, is an LHRH agonist. Zoptarelin doxorubicin is a peptide agonist of the gonadotropin releasing hormone-1 receptor (GnRH-1R) that is conjugated to the anthracycline antibio...