rita — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T1798	RITA	NSC 652287,RITA (NSC 652287)	Mdm2 , DNA Alkylator/Crosslinker , p53 , Autophagy
	RITA (NSC-652287)(NSC-652287) induced cross-links of both DNA-DNA and DNA-protein with no detectable DNA single-strand breaks. RITA, like nutlin-3, can disrupt the p53/Mdm2 interaction.		Mdm2 , DNA Alkylator/Crosslinker , p53 , Autophagy
T3226	Paritaprevir	ABT-450,Veruprevir	HCV Protease
	Paritaprevir (ABT-450) is an orally bioavailable, synthetic acylsulfonamide inhibitor of the hepatitis C virus (HCV) protease complex comprised of non-structural protein 3 and 4A (NS3/NS4A), with potential activity again...		HCV Protease
T16759	Ritanserin	R 55667	Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor , Histamine Receptor
	Ritanserin (R 55667) is a highly effective, relatively selective, long-acting antagonist of 5-HT2 receptor (IC50: 0.9 nM), less active on Histamine H1, Dopamine D2, Adrenergic α1, Adrenergic α2 receptors.
T22394	Paritaprevir	ABT450,ABT-450,Veruprevir	HCV Protease
	Paritaprevir (ABT450) is an inhibitor of non-structural protein 3/4A protease with EC50 values of 1 and 0.21 nM for HCV 1a and HCV 1b, respectively.		HCV Protease
TN1143	1-O-Acetyl britannilactone		NF-κB , COX
	1-O-Acetyl britannilactone shows antifungal, and anti-cancer activities, it suppresses angiogenesis and lung cancer cell growth possibly via regulating the VEGFR-Src-FAK signaling.		NF-κB , COX
T4041	Ziritaxestat	GLPG1690	PDE
	Ziritaxestat (GLPG1690), an autotaxin inhibitor, currently being evaluated in an exploratory phase 2 study in idiopathic pulmonary fibrosis patients.		PDE
T2691	Oritavancin diphosphate	LY333328 diphosphate	Others , Antibacterial , Antibiotic
	Oritavancin diphosphate (LY333328 diphosphate) is a novel semisynthetic glycopeptide antibiotic which is being developed for the treatment of serious Gram-positive bacterial infections.		Others , Antibacterial , Antibiotic
TQ0118	Britannilactone	Desacetylinulicin	Others
	Britannilactone, extracted from the dried flower of Inula britannica L, significantly reduces melanin production in a dose-dependent manner (IC50: 15.5 uM).		Others
T5793	Britannin		Apoptosis , AMPK , Autophagy
	Britannin, a sesquiterpene lactone, inhibits proliferation and induces apoptosis through the mitochondrial signaling pathway in human breast cancer cells.		Apoptosis , AMPK , Autophagy
T31362	Deferitazole	SPD602,FBS 0701,SPD-602,FBS0701,FBS-0701,SPD 602	Others
	Deferitazole (FBS 0701) is a novel and orally active, selective and high affinity iron chelator.		Others
T37881	Oritavancin(LY-333328)
	Oritavancin is a novel semisynthetic glycopeptide antibiotics. On August 6, 2014, the FDA approved oritavancin for treatment of skin infections. Oritavancin possesses potent and rapid bactericidal activity in vitro again...
T68311	Ritanserin tartrate
	Ritanserin tartrateis is a selective and potent serotonin-2 antagonist.
TN2555	1-O-Acetyl-6-O-isobutyrylbritannilactone		Others
	1-O-Acetyl-6-O-isobutyrylbritannilactone is a natural product for research related to life sciences. The catalog number is TN2555 and the CAS number is 1613152-34-3.		Others
T73898	Paritaprevir dihydrate
	Paritaprevir dihydrate (ABT-450), a highly effective and orally administered antiviral, acts as a non-structural protein 3/4A (NS3/4A) protease inhibitor, displaying EC50 values of 1 and 0.21 nM against HCV genotypes 1a ...
T82058	Inubritannolide A
	Inubritannolide A exhibits moderate to robust neuroprotective effects across various neuronal cell types against inducers such as H2O2, 6-hydroxydopamine (6-OHDA), and lipopolysaccharide (LPS).
TN3843	Dibritannilactone B		Others
	Dibritannilactone B is a natural product from Inula britannica.		Others
TN2556	1-O-Acetyl-6alpha-O-(2-methylbutyryl)britannilactone		Others
	1-O-Acetyl-6alpha-O-(2-methylbutyryl)britannilactone is a natural product for research related to life sciences. The catalog number is TN2556 and the CAS number is 1932687-71-2.		Others
T124250	Aceritannin
	Aceritannin is a useful organic compound for research related to life sciences. The catalog number is T124250 and the CAS number is 76746-56-0.
T126430	1-O-Acetyl-6beta-O-Isobutyrylbritannilactone
	1-O-Acetyl-6beta-O-Isobutyrylbritannilactone is a useful organic compound for research related to life sciences and the catalog number is T126430.
T21120	Neritaloside
	Neritaloside is a natural product from Nerium oleander.