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Cat No. | Product Name | Synonyms | Targets |
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T33452 | ML192 | ML-192,CID1434953,CID 1434953,ML 192,CID-1434953 | Cannabinoid Receptor , GPR , Arrestin |
ML192 (CID1434953) is a selective GPR55 ligand antagonist. ML192 is an inhibitor that inhibits β-arrestin transport, ERK1/2 phosphorylation, and PKCβII translocation. | |||
T8371 | ML188 | Virus Protease , SARS-CoV | |
ML188 is a selective noncovalent SARS-CoV 3CLpro inhibitor(IC50 : 1.5 μM), with moderate MW and good enzyme and antiviral inhibitory activity. | |||
T8986 | ML198 | Glucokinase | |
ML198 is a novel activator and non-inhibitory chaperone of glucocerebrosidase. ML198 serves as a starting point to develop a novel approach towards small molecule treatment for patients suffering from Gaucher disease. | |||
T35544 | ML115 | STAT | |
ML115 is a potent and selective activator of transcription 3 (STAT3), with abn EC50 of 2.0 nM, and is inactive against the related STAT1 and NFκB anti-targets. | |||
T6592 | ML133 hydrochloride | ML133 HCl | Potassium Channel |
ML133 hydrochloride (ML133 HCl) is a selective potassium channel inhibitor for Kir2.1 with IC50 of 1.8 μM (pH 7.4) and 290 nM (pH 8.5), has no effect on Kir1.1 and weak activity for Kir4.1 and Kir7.1. | |||
T8514 | LML134 | LML-134 | Histamine Receptor |
LML134 (LML-134) is an inverse agonist of Histamine 3 receptor (H3R)(hH3R cAMP and hH3R bdg with Kis of 0.3 nM and 12 nM). | |||
T2670 | ML167 | NCGC00188654,CID44968231 | DYRK , CDK |
ML167 (CID44968231) is a highly selective Cdc2-like kinase 4 (Clk4) inhibitor. | |||
T8954 | ML179 | ML-179 | Others |
ML179 is a potent and selective inverse agonist of liver receptor homolog-1 (LRH1, NR5A2) with IC50 of 320 nM. | |||
T2463 | ML141 | CID-2950007 | Apoptosis , CDK , Ras |
ML141 (CID-2950007) is an effective, specific and reversible non-competitive inhibitor of Rho family GTPase cdc42 (IC50: 200 nM). | |||
T8970 | ML162 | Ferroptosis , GPX , Glutathione Peroxidase | |
ML162 is an inhibitor of GPX4 that is selectively lethal to mutant RAS oncogene-expressing cell lines (IC50s = 25 and 578 nM for HRASG12V-expressing and wild-type BJ fibroblasts, respectively) | |||
T8597 | ML116 | STAT | |
ML116 is a potent and selective STAT3 inhibitor. | |||
T28063 | ML169 | ML 169,ML-169 | |
ML169 is a selective and brain penetrant M1 positive allosteric modulator (PAM). | |||
T64738 | 16-(S)-ML188 | ||
16-(S)-ML188 is a useful organic compound for research related to life sciences and the catalog number is T64738. | |||
T16105 | ML132 | NCGC 00185682 | Others |
ML132 is an effective and selective inhibitor of caspase 1 (IC50: 0.316 nM). | |||
T62168 | ML138 | ||
ML138 is a probe for MLPCN, an agonist of the κ opioid receptor. |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-03802 | IL-17F Protein, Human, Recombinant (aa 31-163) | Human | E. coli |
Interleukin-17F (IL-17F) is a cytokine that shares sequence similarity with IL17. The most notable role of IL-17 is its involvement in inducing and mediating proinflammatory responses. IL-17 is commonly associated with a... | |||
TMPY-05461 | IL-17F Protein, Human, Recombinant (His), Biotinylated | Human | HEK293 |
Interleukin-17F (IL-17F) is a cytokine that shares sequence similarity with IL17. The most notable role of IL-17 is its involvement in inducing and mediating proinflammatory responses. IL-17 is commonly associated with a... | |||
TMPY-01898 | IL-17F Protein, Human, Recombinant (aa 31-163, His) | Human | HEK293 |
Interleukin-17F (IL-17F) is a cytokine that shares sequence similarity with IL17. The most notable role of IL-17 is its involvement in inducing and mediating proinflammatory responses. IL-17 is commonly associated with a... | |||
TMPK-00042 | IL-17F Protein, Mouse, Recombinant (His & Avi), Biotinylated | Mouse | HEK293 |
The Interleukin 17 (IL-17) family proteins, comprising six members (IL-17A through IL-17F), are secreted, structurally related proteins that share a conserved cystine-knot fold near the C-terminus, but have considerable ... | |||
TMPK-00041 | IL-17F Protein, Mouse, Recombinant (His & Avi) | Mouse | HEK293 |
The Interleukin 17 (IL-17) family proteins, comprising six members (IL-17A through IL-17F), are secreted, structurally related proteins that share a conserved cystine-knot fold near the C-terminus, but have considerable ... | |||
TMPK-00046 | IL-17F Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 |
The Interleukin 17 (IL-17) family proteins, comprising six members (IL-17A through IL-17F), are secreted, structurally related proteins that share a conserved cystine-knot fold near the C-terminus, but have considerable ... | |||
TMPY-01840 | TLT-1/TREML1 Protein, Human, Recombinant (His) | Human | HEK293 |
Trem-like transcript 1 protein, also known as Triggering receptor expressed on myeloid cells-like protein 1, TREML1 and TLT-1, is a cytoplasm and single-pass type I membrane protein. TREML1 / TLT-1 is expressed exclusive... | |||
TMPK-00620 | TLT-1/TREML1 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
Triggering receptor expressed on myeloid cells (TREM)-like transcript-1 (TLT-1) is an immunoreceptor tyrosine-based inhibitory motif (ITIM)-baring TREM family protein. Triggering receptor expressed on myeloid cells (TREM... | |||
TMPJ-00193 | TREML1 Protein, Human, Recombinant (hFc) | Human | Human Cells |
Triggering Receptor Expressed on Myeloid Cells-Like Protein 1 (TREML1) is a single-pass type I membrane protein. TREML1 precursor contains a 15 amino acid signal peptide, a 147 amino acid extracellular domain with an Ig-... |