Powder: -20°C for 3 years | In solvent: -80°C for 1 year
ML116 is a potent and selective STAT3 inhibitor.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 133.00 | |
2 mg | In stock | $ 198.00 | |
5 mg | In stock | $ 297.00 | |
10 mg | In stock | $ 453.00 | |
25 mg | In stock | $ 747.00 | |
50 mg | In stock | $ 1,050.00 | |
100 mg | In stock | $ 1,420.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 298.00 |
Description | ML116 is a potent and selective STAT3 inhibitor. |
In vitro | Probe ML116 exhibits a STAT3 IC50 value of approximately 4 micromolar and does not inhibit the STAT1, STAT5, or NFkB signaling pathways (IC50 values greater than 56 micromolar), as determined using cell-based luciferase reporter assays.?Quantitative PCR experiments demonstrated that probe ML116 inhibits transcription of the STAT3-regulated gene BCL3 |
Molecular Weight | 309.43 |
Formula | C18H19N3S |
CAS No. | 744270-00-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 3.1 mg/mL (10 mM)
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
ML116 744270-00-6 JAK/STAT signaling Stem Cells STAT ML 116 ML-116 inhibitor inhibit