k -atpase — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T1719	Bufalin		ATPase
	Bufalin is an active ingredient and one of the glycosides in the traditional Chinese medicine ChanSu; it is also a bufadienolide toxin originally isolated from the venom of the Chinese toad Bufo gargarizans, with potenti...		ATPase
T0712	Suloctidil		ATPase , Platelet aggregation
	Suloctidil is a peripheral vasodilator that was formerly used in the management of peripheral and cerebral vascular disorders. It is hepatotoxic and fatalities have occurred.		ATPase , Platelet aggregation
T6443	Chloroprocaine hydrochloride	Chloroprocaine HCl	ATPase , Others
	Chloroprocaine hydrochloride (Chloroprocaine HCl) is a local anesthetic during surgical procedures.		ATPase , Others
T0490	Chlorpropamide	Diabinese	ATPase , ABC
	Chlorpropamide (Diabinese) is a sulfonylurea hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification.		ATPase , ABC
T20626	Esomeprazole		Proton pump , Cysteine Protease
	Esomeprazole is the S-isomer of omeprazole, inhibits the lysosomal cysteine protease legumain to prevent cancer metastasis. Esomeprazole is a proton pump inhibitors (PPI).		Proton pump , Cysteine Protease
TJP2872	Acevaltrate	Acevaltratum,Acetoxyvaltrate	ATPase , Others
	1. Acevaltrate (Acevaltratum) displays high cytotoxicity against GLC(4), a human small-cell lung cancer cell line, and against COLO 320, a human colorectal cancer cell line, with IC50 values of 1-6 uM.		ATPase , Others
T6953	Prilocaine	Citanest,Propitocaine,NSC 40027	ATPase , Sodium Channel
	Prilocaine (NSC-40027) is a local anesthetic of the amino amide type, which acts on the sodium channel on the neuronal membrane and limits the spread of seizures.		ATPase , Sodium Channel
T0796	Prilocaine hydrochloride	Prilocaine HCl,Propitocaine hydrochloride,Xylonest	ATPase , Sodium Channel
	Prilocaine hydrochloride (Prilocaine HCl) is a local anesthetic of the amino amide type, binds to voltage-gated sodium ion channels in the neuronal membrane, thereby preventing the permeability of sodium ions.		ATPase , Sodium Channel
T2176	2,3-Butanedione 2-Monoxime	Diacetyl monoxime,2,3-Butanedione-2-monoxime	Akt
	2,3-Butanedione 2-Monoxime (Diacetyl monoxime) is an inhibitor of skeletal and cardiac muscle contraction.		Akt
T0295	Digitoxin	Digitoxoside,Unidigin,Digitoxinum	ATPase , Others
	Digitoxin (Digitoxinum) is an effective Na+/K+-ATPase inhibitor (EC50 value: 0.78 μM).		ATPase , Others
T5S0890	Oleandrin	Neriostene,Folinerin,Foliandrin	Apoptosis , ATPase , Potassium Channel , Sodium Channel
	1. Oleandrin (Folinerin), the principal cardiac glycoside component of PBI-524, can quantitatively account for regulation of BDNF at both the protein and transcriptional levels. 2. Oleandrin are known to inhibit the Na, ...		Apoptosis , ATPase , Potassium Channel , Sodium Channel
T2686L	Esomeprazole Sodium	(S)-Omeprazole sodium	ATPase , Proton pump
	Esomeprazole Sodium ((S)-Omeprazole sodium) is the S-isomer of omeprazole with selective and irreversible proton pump inhibitor activity.Esomeprazole acts as an exosome inhibitor by blocking the exosome release via the i...		ATPase , Proton pump
T2621	Rostafuroxin	PST 2238	ATPase , RSV
	Rostafuroxin (PST 2238) has been used in trials studying the treatment of Essential Hypertension.		ATPase , RSV
TN5073	Strophanthidin	Strophanthidine	ATPase , Calcium Channel
	Strophanthidin (Strophanthidine) can induce calcium overload in vivo.		ATPase , Calcium Channel
T2922	Phlorizin	Floridzin,NSC 2833,Phloridzin	ATPase , SGLT
	Phlorizin (Phloridzin) is a non-selective SGLT inhibitor found in apple, for hSGLT1( Ki=300 nM) and hSGLT2( Ki=39 nM) .		ATPase , SGLT
T8183	Deslanoside	Desacetyllanatoside C,Deacetyllanatoside C	ATPase , Drug Metabolite
	Deslanoside (Desacetyllanatoside C) is a rapidly acting cardiac glycoside used to treat congestive heart failure and supraventricular arrhythmias due to reentry mechanisms. Deslanoside inhibits the Na-K-ATPase membrane p...		ATPase , Drug Metabolite
T2686	Esomeprazole Magnesium	(S)-Omeprazole magnesium,NEXIUM,(-)-Omeprazole magnesium	ATPase , Proton pump
	Esomeprazole Magnesium (NEXIUM) is the S-isomer of omeprazole, can reduce gastric acid secretion with selective and irreversible proton pump inhibitor activity.Esomeprazole magnesium acts as an exosome inhibitor by block...		ATPase , Proton pump
T2O2668	Oleic acid	Elaidoic acid,9Z-Octadecenoic acid,Oleate,9-Octadecenoic Acid,Glycon Wo,9-cis-Octadecenoic acid	Apoptosis , ATPase , Others , Endogenous Metabolite
	Oleic acid (Glycon Wo) is a natural product, a common saturated fatty acid found in a variety of animal and vegetable fats and oils. Palmitic acid is a Na+/K+ ATPase activator.		Apoptosis , ATPase , Others , Endogenous Metabolite
T6928	Pantoprazole	SKF96022,BY1023	Apoptosis , Proton pump , Autophagy
	Pantoprazole (BY1023) is a proton pump inhibitor used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal reflux disease.		Apoptosis , Proton pump , Autophagy
T8386	Esomeprazole Magnesium trihydrate	(S)-Omeprazole magnesium trihydrate	Proton pump
	Esomeprazole Magnesium trihydrate ((S)-Omeprazole magnesium trihydrate) is a proton pump inhibitor indicated for the short-term treatment of gastroesophageal reflux disease in patients with a history of erosive esophagit...		Proton pump