20
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T6546 | IPA-3 | IPA3,IPA 3 | PAK |
IPA-3 is a selective non-ATP competitive Pak1 inhibitor with IC50 of 2.5 μM, no inhibition to group II PAKs (PAKs 4-6). | |||
TP1026 | Tos-Gly-Pro-Arg-ANBA-IPA | tos-GPR-ANBA-IPA | |
Tos-Gly-Pro-Arg-ANBA-IPA is a chromogenic peptide substrate. Tos-Gly-Pro-Arg-ANBA-IPA is used for the rapid and specific photometric assay of recombinant hirudin (r-hirudin). | |||
T5297 | 3-Indolepropionic acid | Indolepropionic acid,IPA,indole-3-propionic acid | Antioxidant , Reactive Oxygen Species , Endogenous Metabolite |
3-Indolepropionic acid (Indolepropionic acid) is shown to be a powerful antioxidant with potential in the treatment for Alzheimer’s disease. | |||
TP1025 | Tos-Gly-Pro-Arg-ANBA-IPA acetate | tos-GPR-ANBA-IPA acetate | |
Tos-Gly-Pro-Arg-ANBA-IPA (acetate) is a peptide substrate for luminescence measurement. | |||
T32099 | Homocysteinylpropachlor | Homo-cys-ipa | |
Homocysteinylpropachlor is a bioactive chemical. | |||
T7809L | Ipamorelin 2 Pivalic acid | NNC-26-0161 | Others |
Ipamorelin 2 Pivalic acid (NNC-26-0161) is a growth-hormone-releasing peptide, induces longitudinal bone growth in rats. | |||
T4950 | 1,2-Dipalmitoyl-sn-glycerol | (S)-1,2-Dipalmitin | Endogenous Metabolite , PKC |
1,2-Dipalmitoyl-sn-glycerol ((S)-1,2-Dipalmitin) is an analog of the PKC-activating second messenger diacylglycerol (DAG). It weakly activates PKC. | |||
T6252 | Ipatasertib | GDC-0068,RG7440 | Akt |
Ipatasertib (GDC-0068) (GDC-0068), a highly specific pan-Akt inhibitor, targets Akt1/2/3 with IC50 of 5 nM/18 nM/8 nM, respectively. | |||
T15374 | Ipatasertib dihydrochloride | GDC-0068 dihydrochloride,RG-7440 dihydrochloride | Akt , PKA |
Ipatasertib dihydrochloride (GDC-0068 dihydrochloride) is a highly selective and ATP-competitive inhibitor of pan-Akt (IC50s: 5, 18 and 8 nM for Akt1, Akt2 and Akt3, respectively). | |||
T5238 | 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine | 1,2-Dipalmitoyl-sn-glycero-3-PE,1,2-Dipalmitoyl-sn-glycerol-3-Phosphoethanolamine,1,2-DPPE | Others , Endogenous Metabolite |
1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine (DPPE), a phospholipid member of the glycerophosphonoethanolamine family, is a major component in biological membranes. Studies focused on interactions between DPPE and ch... | |||
T26296 | Triparanol | MER-29,NSC 65345,NSC-65345,NSC65345 | Apoptosis , Hedgehog/Smoothened |
Triparanol (NSC-65345) interferes with posttranslational modification of Hedgehog signaling molecules as well as the sterol sensing domain of its receptor PTCH1, leading to down-regulation of Hedgehog signaling. Triparan... | |||
TQ0157 | EIPA | L593754,MH 12-43 | Sodium Channel , TRP/TRPV Channel |
EIPA (L593754) (L593754, MH 12-43) is a TRPP3 channel inhibitor (IC50: 10.5 μM). It also inhibits Na+/H+-exchanger (NHE) and macropinocytosis. | |||
T16887 | Sipatrigine | 619C89,BW 619C89 | Calcium Channel , Sodium Channel |
Sipatrigine is a glutamate release inhibitor and voltage-dependent sodium channel. | |||
T6224 | Iniparib | NSC-746045,IND-71677,BSI-201 | PARP , Influenza Virus |
Iniparib (BSI-201) (BSI-201) , a PARP1 inhibitor, exhibits potency in triple-negative breast Y (TNBC). | |||
T68047 | Clopipazan | Others | |
Clopipazan is an antipsychotic and antidepressant compound.Clopipazan has sedative and anxiolytic activity, possibly due to selective GABergic blockade of certain interneurons. | |||
T21460 | Teriparatide acetate | hPTH 1-34 (acetate salt),Parathar acetate,Forteo | Others |
Teriparatide acetate (Forteo) is a PHT agonist, with an IC50 of 2 nM in HEK293 cells.Teriparatide acetate is a recombinant form of parathyroid hormone. It is an effective anabolic (i.e., bone growing) agent used to treat... | |||
T2373 | Vipadenant | CEB-4520,BIIB-014 | Adenosine Receptor |
Vipadenant (CEB-4520)(BIIB-014) is an adenosine A2a antagonist with Ki of 1.3 nM; less potent for A1(Ki=69 nM). | |||
T0345 | Estropipate | Piperazine estrone sulfate,Pipestrone,Estrone sulfate piperazine salt | Estrogen Receptor/ERR , Estrogen/progestogen Receptor |
Estropipate (Piperazine estrone sulfate) is a natural estrogenic substance composed of estrone sulfate and piperazine. | |||
T12480 | Pipamperone | Floropipamide,McN-JR 3345,R 3345 | Others , Dopamine Receptor , 5-HT Receptor |
Pipamperone (McN-JR 3345) binds 5-HT2A closely as receptor. | |||
T26091 | Riparin III | ||
Riparin III is an alcamide isolated from Aniba riparia that has exhibited effects of antidepressant and anxiolytic activities in acute stress behavioral models. |