ec-1 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T9832	(Rac)-EC5026	Urea, N-[3-fluoro-4-(trifluoromethoxy)phenyl]-N'-[1-(2-methyl-1-oxobutyl)-4-piperidinyl]-	Epoxide Hydrolase
	(Rac)-EC5026 ((Rac)-BPN-19186) is a potent piperidine inhibitor of soluble epoxide hydrolase (sEH) with Ki of 0.06 nM. (Rac)-EC5026 can be used for the research of Parkinson's disease and dementia with Lewy Bodies (DLB) ...		Epoxide Hydrolase
T21468	CVT-2738	UNII-NYS3I6283H,CVT 2738,EC 610-916-8,CVT2738,RS-94287	Others
	CVT-2738 (RS-94287) is a metabolite of Ranolazine. Ranolazine is a partial fatty acid oxidation (pFOX) inhibitor and anti-anginal drug.		Others
T21184	Decanenitrile	AI3-11101,Caprinitrile,1-Cyanononane,EC 217-830-6,Decanonitrile
	Decanenitrile is a biochemical.
T21312	Afatinib	Afatinib free base,BIBW 2992	EGFR , Autophagy
	Afatinib (BIBW 2992) is an irreversible inhibitor of EGFR family (EGFR-wt, EGFR-L858R, EGFR-L858R/T790M and HER2 with IC50s of 0.5 nM, 0.4 nM, 10 nM and 14 nM , respectively).		EGFR , Autophagy
T20049	Brilliant Blue	EC 272-939-6,Blue 1 lake,Brilliant Blue FCF Lake
	FD&C Blue No. 1 aluminum lake is an agent of dye.
T1773	Afatinib Dimaleate	BIBW2992,Afatinib,BIBW 2992MA2,Afatinib (BIBW2992) Dimaleate	EGFR , HER , Autophagy
	Afatinib Dimaleate (BIBW 2992MA2) is an orally bioavailable anilino-quinazoline derivative and inhibitor of the receptor tyrosine kinase (RTK) epidermal growth factor receptor (ErbB; EGFR) family, with antineoplastic act...		EGFR , HER , Autophagy
T9147	FEN1-IN-3
	FEN1-IN-3 is a human flap endonuclease-1 ( hFEN1 ) inhibitor that stabilizes hFEN1 with an EC 50 of 6.8 μM .
T3S1892	Crassicauline A	Crassicauline I	Others
	1. Crassicauline A (Crassicauline I) and Yunaconitine possesses feeding deterrent activity against T. castaneum adults, with EC(5) values of 1134.5 and 653.4 ppm, respectively.		Others
T4S0999	(2S)-Isoxanthohumol	Isoxanthohumol	Virus Protease , HSV
	1. (2S)-Isoxanthohumol shows an antiviral activity towards herpes viruses (HSV1 and HSV2) and bovine viral diarrhea virus (BVDV). 2. Isoxanthohumol is a polyphenol with antioxidant, anti-inflammatory, and antiangiogenic ...		Virus Protease , HSV
T9000	Pyrimorph		Antifungal
	Pyrimorph is a fungicide with high activity against the plant pathogen Phytophthora capsici. Pyrimorph inhibited different stages in the life cycle of P. capsici including mycelial growth, sporangium production, zoospore...		Antifungal
T60218	YAP/TAZ inhibitor-2		YAP
	YAP/TAZ inhibitor-2 is a potent and orally active TEAD-YAP/TAZ inhibitor with an EC 50 value of 3 nM. YAP/TAZ inhibitor-2 shows anti-proliferative and antitumor activity [1].		YAP
T60325	Viloxazine	Emovit,Viloxazin	5-HT Receptor , Norepinephrine
	Viloxazine (Viloxazin) (Viloxazin) is a dual-action compound that functions as a norepinephrine reuptake inhibitor and exhibits potent agonistic activity towards 5-HT 2C receptors while acting as an antagonist for 5-HT 2...		5-HT Receptor , Norepinephrine
T6729	Lomibuvir	VX-222,VCH-222	HCV Protease
	Lomibuvir (VCH-222) (VX-222) is a selective, non-nucleoside allosteric inhibitor of HCV NS5B polymerase (RdRp) with a Kd of 17 nM. Lomibuvir inhibits the 1b/Con1 HCV subgenomic replicon with an EC 50 of 5.2 nM. Lomibuvir...		HCV Protease
T40319	PIM-IN-1
	PIM-IN-1 is a pan-PIM kinase inhibitor (KG-1, EC 50 = 61 nM; pS6, EC 50 = 71 nM).
T76670	HMC1R agonist 1
	hMC1R agonist 1, with an EC 50 of 3 nM, exhibits at least 300-fold higher selectivity for hMC1R compared to hMC3R (EC 50 >902 nM), hMC4R (EC 50 >915 nM), and hMC5R (EC 50 >1000 nM). This compound demonstrates potential f...
T79415	Antiparasitic agent-18		Parasite
	Antiparasitic agent-18 (compound 3a) exhibits potent and selective antiprotozoal activity, demonstrating effective inhibition of T. brucei (EC 50 =0.4 µM), T. cruzi (EC 50 =0.21 µM), and L. donovani (EC 50 =0.26 µM) [1].		Parasite
TN3219	7,8-Didehydrocimigenol		ERK , IκB/IKK , TNF , NF-κB , Akt , PPAR
	7,8-Didehydrocimigenol can be used for the treatment of cardiovascular disorders such as atherosclerosis. It upregulates PPAR-γ in EC inhibits NF-kB activity of TNF-α-activated EC which leads to selective inhibition of V...		ERK , IκB/IKK , TNF , NF-κB , Akt , PPAR
T61079	RXFP3 agonist 1
	RXFP3 agonist 1 is a nonpeptide RXFP3 agonist ( EC 50 =6937 nM) [1].
T76046	BigLEN(rat) TFA
	BigLEN(rat) is a potent GPR171 agonist with an EC 50 of 1.6 nM [1] .
T75416	Alpha-1,3-N-Acetylgalactosaminyltransferase (Pm1138)
	Alpha-1,3-N-Acetylgalactosaminyltransferase (Pm1138) (EC 2.4.1.40(Pm1138)), also known as the ABO system transferase, exhibits glycosyl transferase activity [1].