eb — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T11143	EB-47		PARP
	EB-47 mimics the substrate NAD+ and extends from the nicotinamide to the adenosine subsite.EB-47, a potent and selective PARP-1/ARTD-1 inhibitor with an IC50 value of 45 nM, shows modest potency against ARTD5 with an IC...		PARP
T39972	EB-42486		LRRK2
	EB-42486 is an effective and highly selective inhibitor of G2019S-LRRK2 with an IC50 < 0.2 nM.		LRRK2
T7955	EB-3D		Apoptosis , AMPK , AChR
	EB-3D is a potent and selective choline kinase alpha 1 (ChoKα1) inhibitor(IC50 : 1 μM).with anti-cancer activity.		Apoptosis , AMPK , AChR
T22756	EB-47 dihydrochloride	EB 47	Others
	EB 47 is an effective inhibitor of PARP-1 (IC50: 45 nM).		Others
T10758L	Centanafadine hydrochloride	EB-1020 hydrochloride	Dopamine Receptor , Serotonin Transporter , Adrenergic Receptor , Norepinephrine
	Centanafadine hydrochloride (EB-1020 hydrochloride) is a dual inhibitor of norepinephrine (NE)/dopamine (DA) transporter, also inhibits serotonin transporter (IC50s: 6 nM, 38 nM, and 83 nM for human NE, DA, and serotonin...
T6375	Alibendol	cebera,EB 1856	Others
	Alibendol (cebera) is a choleretic, antispasmodic, and cholekinetic.		Others
TD0006	EB Eraser
	The strong EB detoxification agent is specially designed to remove the contaminated product of Ethidium bromide (EB).It can effectively destroy the structure of EB, remove the carcinogenicity of EB, so as to achieve the ...
T1220	Ethidium bromide	EtBr,Homidium bromide,EB	AChR
	Ethidium bromide (EB) A trypanocidal agent and possible antiviral agent that is widely used in experimental cell biology and biochemistry. Ethidium has several experimentally useful properties including binding to nucle...		AChR
T2092	Amitifadine hydrochloride	DOV-21947 hydrochloride,EB-1010 hydrochloride	Dopamine Receptor , 5-HT Receptor , Serotonin Transporter , Norepinephrine
	Amitifadine hydrochloride (EB-1010 hydrochloride) is a triple reuptake inhibitor (TRI) or serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI).
T26254	Teglarinad chloride	GMX 1777 chloride,EB1627,GMX1777,GMX1777 chloride,GMX 1777,GMX-1777 chloride,EB-1627,EB-1627 chloride,EB1627 chloride	NAMPT
	Teglarinad chloride (GMX-1777 chloride) is a potent inhibitor of NAMPT, the precursor of GMX1778.Teglarinad chloride has antitumor activity and acts by interfering with DNA repair and inhibiting angiogenesis.		NAMPT
T62793	EB-0150
	EB-0150 is a potent inhibitor of ER α-glucosidase (α-Glu) I (IC50s: 0.73 μM) and (α-Glu) II (IC50s: 0.0337 μM). EB-0150 is an N-substituted valerian derivative with broad-spectrum antiviral effects. EB-0150 has potential...
T63170	EB-0156
	EB-0156 is a potent inhibitor of ER α-glucosidase (α-Glu) I and II with IC50 values of 0.0479 and <0.001 μM, respectively. EB-0156 is an N-substituted valerian derivative with broad-spectrum antiviral activity. EB-0156 h...
T63303	EB-0176
	EB-0176 is an N-substituted valerian derivative that exhibits broad-spectrum antiviral activity and is a potent ER α-glucosidase (α-Glu) I and II inhibitor with IC50s of 0.6439 and 0.0011 μM, respectively.EB-0176 exhibit...
T23706	Alminoprofen	EB382,EB 382,EB-382
	Alminoprofen is a nonsteroidal anti-inflammatory agent. It was found to significantly suppress passive anaphylactic bronchoconstrictions at 30 mg/kg given intraduodenally.
T10758	Centanafadine	EB-1020	Others
	Centanafadine is a dual inhibitor of norepinephrine (NE)/dopamine (DA) transporter, also inhibits serotonin transporter (IC50s: 6 nM, 38 nM, and 83 nM for human NE, DA, and serotonin transporter).		Others
T19559	Seocalcitol	EB 1089	Others
	Seocalcitol is an analog of vitamin D, binds vitamin D receptor protein from human osteosarcoma MG-63 cells(Kd : 0.27 nM).		Others
T8055	TFEB activator 1	(1E,4E)-1,5-Bis(2-Methoxyphenyl)penta-1,,Curcumin analog compound C1,Curcumin analog C1,RPN77612	Others , Autophagy
	TFEB activator 1 (Curcumin analog compound C1) is an activator of transcription factor EB (TFEB) with promise for the prevention or treatment of Alzheimer's disease.		Others , Autophagy
T8871	C/EBPα inducer 1	4(3H)-Quinazolinone, 6-fluoro-2-[(1E)-2-(5-nitro-2-furanyl)ethenyl]-3-phenyl-	Others
	C/EBPα inducer 1 (4(3H)-Quinazolinone, 6-fluoro-2-[(1E)-2-(5-nitro-2-furanyl)ethenyl]-3-phenyl-) is a potential inducer of myeloid differentiation via upregulation of C/EBP.		Others
T30355	Benzeneboronic acid	Phenylboric acid,Phenyldihydroxyborane,Phenylboronic acid	Others
	Benzeneboronic acid (Phenylboronic acid) is a boronic acid that is used in Mizoroki-Heck and Suzuki-Miyaura coupling reactions.		Others
T6306	Erteberel	LY500307	Estrogen Receptor/ERR , Estrogen/progestogen Receptor
	Erteberel (LY500307) is a potent, selective estrogen receptor β agonist with EC50 of 0.66 nM, 32-fold selectivity against estrogen receptor α. Phase 2.		Estrogen Receptor/ERR , Estrogen/progestogen Receptor