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Alibendol

Catalog No. T6375 CAS 26750-81-2

Synonyms: cebera, EB 1856

Alibendol (cebera) is a choleretic, antispasmodic, and cholekinetic.

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Alibendol, CAS 26750-81-2

Pack Size	Availability	Price/USD	Quantity
500 mg	In stock	$ 42.00
1 mL * 10 mM (in DMSO)	In stock	$ 46.00

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Purity: 99.14%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Alibendol (cebera) is a choleretic, antispasmodic, and cholekinetic.

Kinase Assay

Enzyme Assays: Assays measuring the enzyme-catalyzed phosphorylation of GST-IκBα are performed by adding enzyme (a final concentration of 0.5 μg/mL) at 30 ℃ to solutions of 100 μg/mL GST- IκBα and 5 μM [33P]ATP in 40 mM Tris HCl, pH 7.5, containing 4 mM MgCl2, 34 mM sodium phosphate, 3 mM NaCl, 0.6 mM potassium phosphate, 1 mM KCl, 1 mM dithiothreitol, 3% (w/v) glycerol, and 250 μg/mL bovine serum albumin. The specific activity of [33P]ATP used in the assay is 100 Ci/mmol. After 5 min, the kinase reactions are stopped by the addition of 2× Laemmli sample buffer and heat-treated at 90 ℃ for 1 min. The samples are then loaded on to NuPAGE 10% BisTris gels. After completion of SDS-PAGE, gels are dried on a slab gel dryer. The bands are then detected using a 445Si PhosphorImager, and the radioactivity is quantified using ImageQuant software. Under these conditions, the degree of phosphorylation of GST-IκBα is linear with time and concentration of enzyme.

Synonyms	cebera, EB 1856
Molecular Weight	251.28
Formula	C13H17NO4
CAS No.	26750-81-2

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 47 mg/mL (187 mM)

H2O: < 1 mg/mL (insoluble or slightly soluble)

Ethanol: 47 mg/mL (187 mM)

References and Literature

1. Sheng, L., H. Chen, and Y. Li,et al. J Chromatogr B Analyt Technol Biomed Life Sci, 2007. 854(1-2): p. 99-103.

Related compound libraries

This product is contained In the following compound libraries：

Drug Repurposing Compound Library FDA-Approved & Pharmacopeia Drug Library Bioactive Compounds Library Max Approved Drug Library NO PAINS Compound Library Bioactive Compound Library

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Alibendol 26750-81-2 Others cebera EB-1856 inhibit EB 1856 EB1856 Inhibitor inhibitor

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.