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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T3189 | B7/CD28 interaction inhibitor 1 | CTLA-4 inhibitor | Others |
B7/CD28 interaction inhibitor 1 (CTLA-4 inhibitor) is a potent CTLA-4 inhibitor. | |||
T78261 | Anti-Mouse CTLA-4 Antibody (9D9) | ||
Anti-Mouse CTLA-4 Antibody is a mouse-derived IgG2b inhibitor targeting CTLA-4 in murine systems. | |||
T9906 | Ipilimumab | Others | |
Ipilimumab (anti-CTLA-4) is an immunomodulatory monoclonal antibody directed against the cell surface antigen CTLA-4 and also a type of immune checkpoint inhibitor. | |||
T77466 | Tremelimumab | Ticilimumab,CP-675206 | Others |
Tremelimumab is a cytotoxic T-lymphocyte-associated antigen-4 (CTLA-4) blocking antibody.Tremelimumab is often used in combination with Durvalumab for the treatment of solid cancers such as hepatocellular carcinoma and l... | |||
T6741 | SPDP | SPDP Crosslinker | Others |
SPDP is a short-chain crosslinker, which is used for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteine sulfhydryls. SPDP could ... | |||
T81329 | Quavonlimab | MK-1308 | |
Quavonlimab (MK-1308) is a novel antibody targeting CTLA-4 [1]. | |||
T76952 | Zalifrelimab | ||
Zalifrelimab (AGEN1884) is a fully human IgG1 monoclonal antibody that targets CTLA-4 (CTLA-4), functioning by antagonizing the CTLA-4-signaling-regulated inhibitory checkpoints of immune cell activation. | |||
T77103 | Nurulimab | ||
Nurulimab (BCD-145) is a humanized monoclonal antibody targeting cytotoxic T lymphocyte antigen-4 (anti-CTLA-4). It has potential applications in melanoma research [1]. | |||
T82268 | Gotistobart | BNT 316,ONC-392 | |
Gotistobart (ONC-392) is a humanized anti-CTLA-4 antibody that enhances immunotherapy by selectively depleting regulatory T cells (Treg) within the tumor microenvironment [1]. | |||
T81124 | Sovipostobart | ||
Sovipostobart, an immunoglobulin G1-kappa monoclonal antibody targeting CTLA-4 in Homo sapiens, features a cleavable prodomain. This compound serves as both an immunostimulant and antineoplastic [1]. | |||
T76728 | Vudalimab | ||
Vudalimab, a fully humanized bispecific monoclonal antibody, effectively inhibits both PD-1 and CTLA-4 immune checkpoint receptors. This dual action facilitates the selective activation of T-cells targeting tumors. | |||
T77072 | Lorigerlimab | ||
Lorigerlimab (MGD019) is a bispecific IgG4 dual-affinity re-targeting (DART) antibody that blocks both PD-1 and CTLA-4, enhancing T-cell responses. It is under investigation for the treatment of metastatic castration-res... | |||
T80598 | Davoceticept | CD80 vIgD-Fc,ALPN-202 | |
Davoceticept (ALPN-202; CD80 vIgD-Fc), a monoclonal antibody that targets CTLA-4, is comprised of the (1-107) fragment of CD80 fused to the IGHG1 Fc domain through a peptidyl linker. It is commonly produced in CHO (Chine... | |||
T76859 | Bavunalimab | ||
Bavunalimab (Anti-Human CTLA4xLAG3), a bispecific human monoclonal antibody targeting CTLA-4 and LAG-3, activates T cells in NSG mice and is utilized in cancer research [1]. | |||
T76933 | Botensilimab | ||
Botensilimab (AGEN 1181), a humanized monoclonal antibody targeting cytotoxic T-lymphocyte antigen 4 (CTLA-4), functions as an activator of both innate and adaptive immunity. It is currently being researched for its pote... | |||
T76968 | Tuvonralimab | ||
Tuvonralimab (PSB-205; QL1706), comprising a combination of Iparomlimab and Tuvonralimab [1], functions as a dual immune checkpoint inhibitor through its formulation of anti-PD-1 IgG4 and anti-CTLA-4 IgG1 antibodies. |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-01604 | CTLA-4 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
CTLA-4 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.46 kDa and the accession number is Q6GTR6. | |||
TMPY-04824 | CTLA-4 Protein, Human, Recombinant | Human | HEK293 Cells |
CTLA-4 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 13.5 kDa and the accession number is P16410-1. | |||
TMPY-04348 | CTLA-4 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
CTLA-4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15 kDa and the accession number is P16410-1. | |||
TMPY-01721 | CTLA-4 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
CTLA-4 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 41 kDa and the accession number is Q6GTR6. | |||
TMPJ-00107 | CTLA-4 Protein, Human, Recombinant (Flag) | Human | HEK293 Cells |
CTLA-4 Protein, Human, Recombinant (Flag) is expressed in HEK293 mammalian cells with C-Flag tag. The predicted molecular weight is 20 KDa and the accession number is P16410. | |||
TMPJ-00635 | CTLA-4 Protein, Cynomolgus, Recombinant (hFc) | Cynomolgus | HEK293 Cells |
CTLA-4 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 45-60 KDa and the accession number is G7PL88. | |||
TMPJ-00636 | CTLA-4 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells |
CTLA-4 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 17-25 KDa and the accession number is G7PL88. | |||
TMPY-05002 | CTLA-4 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
CTLA-4 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 40.7 kDa and the accession number is P16410-1. | |||
TMPY-04998 | CTLA-4 Protein, Human, Recombinant (rFc) | Human | HEK293 Cells |
CTLA-4 Protein, Human, Recombinant (rFc) is expressed in HEK293 mammalian cells with rFc tag. The predicted molecular weight is 39.7 kDa and the accession number is P16410-1. | |||
TMPY-04968 | CTLA-4 Protein, Mouse, Recombinant (His), Biotinylated | Mouse | HEK293 Cells |
CTLA-4 Protein, Mouse, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.3 kDa and the accession number is Q6GTR6. | |||
TMPJ-00640 | CTLA-4 Protein, Cavia porcellus, Recombinant (His) | Cavia porcellus | P. pastoris (Yeast) |
CTLA-4 Protein, Cavia porcellus, Recombinant (His) is expressed in P. pastoris yeast expression system with C-6xHis tag. The predicted molecular weight is 18-40 KDa and the accession number is H0VUB1. | |||
TMPY-04948 | CTLA-4 Protein, Human, Recombinant (His), Biotinylated | Human | HEK293 Cells |
CTLA-4 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15 kDa and the accession number is P16410-1. | |||
TMPJ-00108 | CTLA-4 Protein, Human, Recombinant (GST) | Human | HEK293 Cells |
CTLA-4 Protein, Human, Recombinant (GST) is expressed in HEK293 mammalian cells with C-GST tag. The predicted molecular weight is 40-55 KDa and the accession number is P16410. | |||
TMPJ-00420 | CTLA-4 Protein, Mouse, Recombinant (Flag) | Mouse | HEK293 Cells |
Mouse Cytotoxic Tlymphocyte 4(CTLA-4,CD152), is a type I transmembrane T cell inhibitory molecule. Within the ECD, Mouse CTLA-4 shares 68% aa sequence identity with human. CTLA4 is similar to the T cell costimulatory pro... | |||
TMPY-06326 | CTLA-4 Protein, Mouse, Recombinant (His & Avi), Biotinylated | Mouse | HEK293 Cells |
CTLA-4 Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 17.27 kDa and the accession number is NP_033973.2. | |||
TMPY-06824 | CTLA-4 Protein, Human, Recombinant (hFc & Avi), Biotinylated | Human | HEK293 Cells |
CTLA-4 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 42.89 kDa and the accession number is NP_005205.2. | |||
TMPY-05369 | CTLA-4 Protein, Human, Recombinant (hFc), Biotinylated | Human | HEK293 Cells |
CTLA-4 Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 40.7 kDa and the accession number is P16410-1. | |||
TMPK-00112 | CTLA-4 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
CTLA-4 (cytotoxic T-lymphocyte-associated protein 4), also known as CD152, is a protein receptor that, functioning as an immune checkpoint, downregulates immune responses.CTLA4 is constitutively expressed in regulatory T... | |||
TMPY-02557 | CTLA-4 Protein, Rat, Recombinant (His) | Rat | HEK293 Cells |
CTLA-4 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.2 kDa and the accession number is Q62859. | |||
TMPY-02411 | CTLA-4 Protein, Canine, Recombinant (His) | Canine | HEK293 Cells |
CTLA-4 Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.8 kDa and the accession number is A0A8C0TW59. | |||
TMPY-00620 | CTLA-4 Protein, Canine, Recombinant (hFc) | Canine | HEK293 Cells |
CTLA-4 Protein, Canine, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 40.1 kDa and the accession number is A0A8C0TW59. | |||
TMPY-02492 | CTLA-4 Protein, Rat, Recombinant (hFc) | Rat | HEK293 Cells |
CTLA-4 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 40.5 kDa and the accession number is Q62859. | |||
TMPY-03359 | CTLA-4 Protein, Cynomolgus, Rhesus, Recombinant (hFc) | Cynomolgus,Rhesus | HEK293 Cells |
CTLA-4 Protein, Cynomolgus, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 40.4 kDa and the accession number is Q9BDC4. | |||
TMPJ-00555 | B7-2 Protein, Human, Recombinant (Avi & His), Biotinylated | Human | HEK293 Cells |
B7-2 Protein, Human, Recombinant (Avi & His), Biotinylated is expressed in HEK293 mammalian cells with C-Avi-6xHis tag. The predicted molecular weight is 55-80 KDa and the accession number is AAH40261.1. | |||
TMPJ-00556 | B7-2 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
B7-2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 57-66 KDa and the accession number is AAH40261.1. | |||
TMPJ-00958 | B7-1 Protein, Rabbit, Recombinant (His) | Rabbit | HEK293 Cells |
Cluster of Differentiation 80, also called B7-1, is a member of cell surface immunoglobulin superfamily which plays key, yet distinct roles in the activation of T cells. B7-1/CD80 and B7-2/CD86, together with their recep... | |||
TMPK-00178 | B7-1 Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
Cluster of differentiation 80 (also CD80 and B7-1) is a protein found on dendritic cells, activated B cells and monocytes that provides a costimulatory signal necessary for T cell activation and survival. It is the ligan... | |||
TMPK-00179 | B7-1 Protein, Human, Recombinant (aa 35-242, His & Avi), Biotinylated | Human | HEK293 Cells |
Cluster of differentiation 80 (also CD80 and B7-1) is a protein found on dendritic cells, activated B cells and monocytes that provides a costimulatory signal necessary for T cell activation and survival. It is the ligan... | |||
TMPK-00882 | B7-2 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
B7-1 and B7-2 are homologous costimulatory ligands expressed on the surface of antigen presenting cells (APCs). Binding of these molecules to the T cell costimulatory receptors, CD28 and CTLA-4, is essential for the acti... | |||
TMPJ-00630 | B7-1 Protein, Cynomolgus, Recombinant (hFc) | Cynomolgus | HEK293 Cells |
Cynomologous Cluster of Differentiation 80, also called B7-1, is a member of cell surface immunoglobulin superfamily.It is expressed on the surface of antigen-presenting cells including activated B cells, macrophages and... | |||
TMPK-00880 | B7-2 Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
B7-1 and B7-2 are homologous costimulatory ligands expressed on the surface of antigen presenting cells (APCs). Binding of these molecules to the T cell costimulatory receptors, CD28 and CTLA-4, is essential for the acti... | |||
TMPK-00881 | B7-2 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
B7-1 and B7-2 are homologous costimulatory ligands expressed on the surface of antigen presenting cells (APCs). Binding of these molecules to the T cell costimulatory receptors, CD28 and CTLA-4, is essential for the acti... | |||
TMPK-00087 | ICOS Protein, Human, Recombinant (C136S & C137S, His) | Human | HEK293 Cells |
Inducible co-stimulator (ICOS), also called AILIM (activiation-inducible lymphocyte immunomediatory molecule) and CRP-1 (CD28-related protein-1), is a member of the growing CD28 family of immune costimulatory receptors. ... | |||
TMPK-00653 | B7-2 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells |
B7-1 and B7-2 are homologous costimulatory ligands expressed on the surface of antigen presenting cells (APCs). Binding of these molecules to the T cell costimulatory receptors, CD28 and CTLA-4, is essential for the acti... | |||
TMPK-00086 | ICOS Protein, Human, Recombinant (aa 21-134, His) | Human | HEK293 Cells |
Inducible co-stimulator (ICOS), also called AILIM (activiation-inducible lymphocyte immunomediatory molecule) and CRP-1 (CD28-related protein-1), is a member of the growing CD28 family of immune costimulatory receptors. ... | |||
TMPJ-00181 | PD-1 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
Programmed cell death protein 1(PDCD1) is a single-pass type I membrane protein and contains 1 Ig-like V-type domain. PD-1 is a member of the extended CD28/CTLA-4 family of T cell regulators. PDCD1 inhibits the T-cell pr... | |||
TMPJ-00864 | VEGF165 Protein, Human, Recombinant | Human | HEK293 Cells |
Human Vascular endothelial growth factor (VEGF), also known as VEGF-A and vascular permeability factor (VPF), belongs to the platelet-derived growth factor family of cysteine-knot growth factors. It is a potent activator... | |||
TMPY-00749 | FGF-2 Protein, Human, Recombinant | Human | E. coli |
FGF-2 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 16.5 kDa and the accession number is P09038-4. | |||
TMPK-00823 | VEGF165 Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
Vascular endothelial growth factor (VEGF or VEGF-A), also known as vascular permeability factor (VPF), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. VEGF165 appears to be the most a... | |||
TMPY-04911 | VEGF165 Protein, Human, Recombinant (His & Avi), Biotinylated | Human,Cynomolgus | HEK293 Cells |
VEGF165 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 23.1 kDa and the accession number is P15692-4. | |||
TMPJ-00129 | BTLA Protein, Human, Recombinant (His) | Human | HEK293 Cells |
B- and T-Lymphocyte Attenuator (BTLA) is a single-pass type I membrane protein containing 1 Ig-like V-type (immunoglobulin-like) domain. BTLA expression is induced during activation of T cells, and BTLA remains expressed... | |||
TMPY-04471 | APEG1 Protein, Human, Recombinant (His) | Human | E. coli |
Striated muscle preferentially expressed protein kinase, also known as aortic preferentially expressed protein 1, APEG-1, SPEG and KIAA1297, is a protein that belongs to the protein kinase superfamily and CAMK Ser/Thr pr... | |||
TMPY-02893 | NT5C3A/NT5C3 Protein, Human, Recombinant | Human | E. coli |
NT5C3A (5'-Nucleotidase, Cytosolic IIIA) is a Protein Coding gene. This gene encodes a member of the 5'-nucleotidase family of enzymes that catalyze the dephosphorylation of nucleoside 5'-monophosphates. The encoded prot... | |||
TMPK-00423 | CD45 Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
PTPRC (also known as CD45),T cells require the protein tyrosine phosphatase CD45 to detect and respond to antigen because it activates the Src family kinase Lck, which phosphorylates the T cell antigen receptor (TCR) com... | |||
TMPK-00822 | VEGF165 Protein, Human, Recombinant (His & Avi), FITC-Labeled | Human | HEK293 Cells |
Vascular endothelial growth factor (VEGF or VEGF-A), also known as vascular permeability factor (VPF), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. VEGF165 appears to be the most a... | |||
TMPY-04754 | CASK Protein, Human, Recombinant | Human | Baculovirus Insect Cells |
CASK Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 102.1 kDa and the accession number is O14936-4. | |||
TMPY-01822 | PTK9 Protein, Human, Recombinant (His & GST) | Human | E. coli |
PTK9 Protein, Human, Recombinant (His & GST) is expressed in E. coli expression system with His and GST tag. The predicted molecular weight is 57 kDa and the accession number is Q12792-4. | |||
TMPK-00424 | CD45 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
PTPRC (also known as CD45),T cells require the protein tyrosine phosphatase CD45 to detect and respond to antigen because it activates the Src family kinase Lck, which phosphorylates the T cell antigen receptor (TCR) com... | |||
TMPJ-00782 | Amyloid Precursor Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
Amyloid precursor protein (APP) is a type I membrane protein with several isoforms due to alternative splicing, performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and... | |||
TMPY-00380 | ANTXR2 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
ANTXR2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 57.4 kDa and the accession number is P58335-4. | |||
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