complete — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T10466	BAY-1797		P2X Receptor
	BAY-1797 is an orally active and selective P2X4 antagonist (IC50: 211 nM against human P2X4) with anti-nociceptive and anti-inflammatory effects. BAY-1797 displays no or very weak activity on the other P2X ion channels.		P2X Receptor
T2067	NS11394	NS 11394	GABA Receptor
	NS11394 is a effective and subtype-selective GABA(A) receptor-positive modulator; possesses a functional efficacy selectivity profile of α(5) > α(3) > α(2) > α(1) at GABA(A) alpha subunit-containing receptors.		GABA Receptor
T1486	Oseltamivir phosphate	GS 4104	Influenza Virus
	Oseltamivir phosphate (GS 4104) is the phosphate salt of oseltamivir, a synthetic derivative prodrug of ethyl ester with antiviral activity. By blocking neuraminidases on the surfaces of influenza viruses, oseltamivir in...		Influenza Virus
T23396	ST1936	ST 1936 oxalate	5-HT Receptor
	ST1936 (ST 1936 oxalate) is a selective and potent 5-HT6 receptor agonist that inhibits human 5-HT6, 5-HT7, and 5-HT2B receptors, and stimulates cAMP, Ca2+, ERK1/2, and Fyn kinases through the complete activation of the ...		5-HT Receptor
TQ0039	(±)-Zanubrutinib	(±)-BGB-3111	BTK
	(±)-Zanubrutinib ((±)-BGB-3111) is a potent and orally available Bruton's tyrosine kinase (Btk) inhibitor that demonstrates superior oral bioavailability, achieving higher exposure and more complete target inhibi.		BTK
T70388	(S)-Enitociclib	VIP152	CDK
	(S)-Enitociclib (VIP152) is a selective CDK9 inhibitor that induces complete regression of MYC+ lymphomas by inhibiting RNA polymerase II-mediated transcription of anti-apoptotic and pro-survival proteins.		CDK
T22986	MK 1903		GPR
	MK 1903 is a potent and selective complete agonist for the hydroxy-carboxylic acid receptor 2 (HCA2). HCA2 is also known as G protein-coupled receptor 109A(GPR109A). MK 1903 reduced Foschlin-induced cAMP production in un...		GPR
T6075	Epothilone B	Patupilone,EPO 906	Apoptosis , Microtubule Associated , Antibiotic , Antifungal
	Epothilone B (EPO 906) is a compound isolated from the myxobacterium Sorangium cellulosum. Similar to paclitaxel, patupilone induces microtubule polymerization and stabilizes microtubules against depolymerization conditi...
T1549	Raloxifene hydrochloride	LY156758 hydrochloride,Raloxifene HCl,LY139481 hydrochloride,Keoxifene hydrochloride,LY156758 (Keoxifene) HCl	Estrogen Receptor/ERR , Others , MAO , Estrogen/progestogen Receptor , Autophagy
	Raloxifene hydrochloride (LY156758 hydrochloride) is a second generation selective estrogen receptor modulator (SERM) used to prevent osteoporosis in postmenopausal women. It has estrogen agonist effects on bone and chol...
T9808	Tetradecylthioacetic acid		PPAR
	Tetradecylthioacetic acid is a synthetic fatty acid with a sulfur substitution in the β-position. This modification renders TTA unable to undergo complete β-oxidation and increases its biological activity, including acti...		PPAR
T9542	NS3861		AChR
	NS3861 is an agonist of nicotinic acetylcholine receptors (nAChRs) and bind with high affinity to heteromeric α3β4 and α4β2 nAChRs. NS3861 displays the β-subunit preference and a complete lack of activation at α4-contain...		AChR
T36466	Chlorin E6	Ce6,Chlorin e6,CE6	Parasite
	Chlorin E6 (CE6) is a second-generation photosensitizer with antitumor activity when used in combination with irradiation. In a mouse model of implanted fibrosarcoma, Chlorin E6 (2.5-10 mg/kg, i.v., 50-200 J/cm2 irradiat...		Parasite
T21543	AP 18		TRP/TRPV Channel
	AP-18 is a potent and selective TRPA1 inhibitor. AP-18 inhibits activation of TRPA1 induced by 50 μM Cinnamaldehyde with an IC50 of 3.1 μM and 4.5 μM for human and mouse TRPA1, respectively. AP-18 could reverse complete ...		TRP/TRPV Channel
T39527	Se-DMC
	Se-DMC effectively reduces the inflammatory response, nociception, and neurobehavioral deficits induced by complete Freund's adjuvant (CFA) in mice.
T70681	G-4120
	G-4120 is a biochemical that has been shown to have a dose-dependent complete inhibition of arterial and venous thrombosis.
T69989	(S)-Pomalidomide
	(S)-Pomalidomide is an inhibitor of angiogenesis and growth of B-cell neoplasias, which induces complete regressions of Burkitt's lymphoma cell tumors.
T62266	PPARα agonist 1
	PPARα agonist 1 is a complete and potent PPARα agonist.
T39938	M-1211
	M 1121 is a covalent and orally active inhibitor of the menin-MLL interaction capable of achieving complete and persistent tumor regression.
T61305	LasR-IN-3
	LasR-IN-3, a chemical compound, acts as an inhibitor of LasR in Pseudomonas aeruginosa. It induces structural instability in LasR and causes complete dissociation of its functioning dimeric form [1].
T15167	Draflazine	R-75231	Others
	Draflazine is an ENT1 inhibitor. It completely reverses the hypersensitivity in the complete Freund’s adjuvant (CFA) model of mechanical hyperalgesia. Draflazine also completely reverses the hypersensitivity of the carra...		Others