cd-1 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T10721	CD73-IN-1		CD73
	CD73-IN-1 is a CD73 inhibitor with anticancer activity.		CD73
T14913	CD38 inhibitor 1		CD38
	CD38 inhibitor 1 is an inhibitor of CD38. For hCD38 and mouse CD38, the IC50s are 7.3 nM and 1.9 nM.		CD38
T60054	EJMC-1	N-(3-chloro-4-hydroxyphenyl)-2-oxo-1,2-dihydrobenzo[cd]indole-6-sulfonamide	TNF
	EJMC-1 is an inhibitor of TNF-α with an IC50 value of 42 μM and can be used in studies about auto-inflammatory diseases.		TNF
T36692	Fanotaprim		DHFR
	Fanotaprim is a dihydrofolate reductase (DHFR) inhibitor. Fanotaprim inhibits the growth of T. gondii strains with a TgDHFR IC50 of 1.57 ± 0.11 nM and a hDHFR IC50 of 308 ± 71 nM and a hDHFR to TgDHFR selectivity ratio o...		DHFR
T4371	CD437	AHPN,O-Desmethyl Adapalene,Apoptosis Activator VI	Retinoid Receptor , Autophagy
	CD437 (AHPN) is a specifc Retinoic Acid Receptor γ (RARγ) agonist.		Retinoid Receptor , Autophagy
T50110	CD532		Aurora Kinase
	CD532 is A highly potent Aurora A kinase inhibitor with an IC50 value of 45 nM. CD532 can block Aurora A kinase activity, drive MYCN degradation, and can directly interact with AURKA and induce global conformational tran...		Aurora Kinase
T26619	Amitivir	LY217896,LY 217896,LY-217896	Others , Influenza Virus
	Amitivir (LY 217896) is an inosine monophosphate dehydrogenase inhibitor. Amitivir inhibits the replication of dividing MDCK cells. Amitivir was associated with asymptomatic rises in serum uric acid levels and was ineffe...		Others , Influenza Virus
T40187	GNF2133		DYRK
	GNF2133 is an effective and selective inhibitor of DYRK1A with IC50s of 6.2 nM. GNF2133 can be used in studies about type 1 diabetes.		DYRK
T73718	N-methyl-N-dithiocarboxyglucamine sodium
	N-methyl-N-dithiocarboxyglucamine (MDCG) sodium effectively mobilizes and enhances the excretion of metallothionein-bound 109 Cd in a mouse model, significantly reducing the Cd content in the liver and kidney, the organs...
TP1882L1	Orphanin FQ(1-11) acetate(178249-41-7 free base)		Opioid Receptor
	Peptide fragment containing amino acids 1-11 of Nociceptin. Potent agonist of the ORL1/KOR-3 receptor (Ki = 55 nM); displays no affinity for opioid receptors, including μ, δ, κ1 and κ3 receptors (Ki >1000 nM). Displays a...		Opioid Receptor
T6S0119	Dauricine		Apoptosis , Others , NF-κB
	1. Dauricine has pulmonary toxicity, can produce pulmonary injury in CD-1 mice by the metabolism of Dauricine mediated by CYP3A. 2. Dauricinec can pass the blood-brain barrier, and that P-glycoprotein has an important ro...		Apoptosis , Others , NF-κB
T4S0498	Glaucocalyxin A	Wangzaozin B,Leukamenin F	Apoptosis , Akt , Caspase , PI3K
	1. Glaucocalyxin A (Leukamenin F)-SBE-β-CD could be useful with a better solubility and sustained function in drug delivery. 2. Glaucocalyxin A activates caspase-3, decreases BAD phosphorylation, and reduces the expressi...		Apoptosis , Akt , Caspase , PI3K
T4647	M2I-1	M2I 1	Others
	M2I-1 a small Mad2 inhibitor-1. the first small molecule inhibitor targeting the binding of Mad2 to Cdc20, an essential proteinprotein interaction (PPI) within the SAC. It can disturbs conformational dynamics of Mad2 cri...		Others
T3824	Jaceosidin		Apoptosis , BCL , COX , UGT
	Jaceosidin has anti-oxidative activity. Jaceosidin has anti-inflammatory activity, also a microglial inhibitor with anti-neuroinflammation activity. aceosidin has anticancer activity, modulates the ERK/ATM/Chk1/2 pathway...		Apoptosis , BCL , COX , UGT
T83582	(±)-Pantothenic acid	(±)-Vitamin B5,(±)-Pantothenate
	(±)-Pantothenic acid ((±)-Pantothenate), a B-vitamin, is essential for coenzyme A (CoA) biosynthesis in mammalian cells and exhibits protective activity against valproic acid (VPA)-induced neural tube defects (NTD) in CD...
T80560	Tulisokibart	PRA-023,PRA023
	Tulisokibart (PRA023) is a humanized IgG1-κ monoclonal antibody that targets TNFSF15/TL1A, with potential applications in researching various inflammatory and fibrotic diseases, including Crohn's Disease (CD) [1] [2].
T80559	Duvakitug
	Duvakitug, a humanized IgG1-λ2 monoclonal antibody, targets TNFSF15/TL1A and is primarily expressed in CHOK1SV cells with endogenous glutamine synthetase (GS) activity. It has applications in the research of Crohn's Dise...
TP1882	Orphanin FQ(1-11)	Orphanin FQ (1-11)
	Peptide fragment containing amino acids 1-11 of Nociceptin. Potent agonist of the ORL1/KOR-3 receptor (Ki = 55 nM); displays no affinity for opioid receptors, including μ, δ, κ1 and κ3 receptors (Ki >1000 nM). Displays a...
T81025	Teduglutide TFA	ALX-0600 TFA
	Teduglutide TFA, a dipeptidyl peptidase IV-resistant glucagon-like peptide-2 (GLP-2) analogue, exhibits trophic effects on the gut mucosa and is used in research related to short bowel syndrome (SBS) and Crohn's disease ...
T75897	Orphanin FQ(1-11) TFA
	Orphanin FQ(1-11) TFA, a fragment of orphanin FQ or nociceptin (OFQ/N), acts as a powerful NOP receptor (ORL-1; OP4) agonist, exhibiting a K i of 55 nM. It lacks affinity for μ, δ, κ1, and κ3 receptors (K i >1000 nM), de...