bbb — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T33467	MOMIPP		PI3K
	MOMIPP is a PIKfyve inhibitor and a macropinocytosis inducer. MOMIPP readily penetrates the blood-brain barrier and is moderately effective in suppressing progression of intracerebral glioblastoma xenografts[1][2].		PI3K
T22782	FGIN-1-27		Others
	high affinity agonist of the translocator protein		Others
T6058	LY2886721		Beta-Secretase , BACE
	LY2886721, a BACE inhibitor, is used for the therapy of Alzheimer's Disease.		Beta-Secretase , BACE
T2423	P7C3-A20		Others
	P7C3-A20 is a derivative of P7C3 that has proneurogenic and neuroprotective activity.		Others
T2225	4-Hydroxyantipyrine		COX
	4-Hydroxyantipyrine is formed during oxidative deamination of aminopyrine.		COX
T8551	Nitrobenzylthioinosine	NBMPR	AChR , Adenosine Receptor
	Nitrobenzylthioinosine (NBMPR) is an inhibitor of ENT1 transporter that binds to ENT1 transporter with high affinity.		AChR , Adenosine Receptor
T2671	Regadenoson	CVT-3146,Lexiscan	Adenosine Receptor
	Regadenoson (CVT-3146) is an adenosine derivative and selective A2A adenosine receptor agonist with coronary vasodilating activity. Upon administration, regadenoson selectively binds to and activates the A2A adenosine re...		Adenosine Receptor
T1993	J-147	J147	Epigenetic Reader Domain , Dopamine Receptor , Monoamine Oxidase
	J-147 is an experimental drug with reported effects against both Alzheimer's disease and ageing in mouse models of accelerated aging. It is a curcumin derivative and a potent neurogenic and neuroprotective drug candidate...
T24055	FAUC 213	FAUC213,FAUC-213	Dopamine Receptor
	FAUC 213 is a selective full antagonist of the dopamine D4 receptor.		Dopamine Receptor
T6830	Epoxomicin	BU-4061T,BU-4061T,Aids010837	Apoptosis , Proteasome
	Epoxomicin (BU-4061T,Aids010837) is a selective proteasome inhibitor with anti-inflammatory activity, inhibits primarily the CH-L activity of the 20S proteasome, while T-L and PGPH catalytic activities are also inhibited...		Apoptosis , Proteasome
T9687	MAGL-IN-4	His121 ARG57	Lipase
	MAGL-IN-4 (His121 ARG57) is one of the monoacylglycerol lipase (MAGL) inhibitors in central nervous system-related diseases.		Lipase
T2344	LY 344864	LY344864	5-HT Receptor
	LY 344864, a specifc receptor agonist, is an affinity of 6 nM (Ki) at the recently cloned 5-HT1F receptor.		5-HT Receptor
T1065	Baclofen	Lioresal	GABA Receptor
	Baclofen (Lioresal) is a synthetic chlorophenyl-butanoic acid derivative used to treat spasms due to spinal cord damage and multiple sclerosis, muscle-relaxing Baclofen acts as a gamma-aminobutyric acid (GABA) agonist sp...		GABA Receptor
T9146	Ms48107	Benzenemethanol, 2-[4-amino-6-[[(4-phenoxyphenyl)methyl]amino]-1,3,5-triazin-2-yl]-3-fluoro-	Others
	MS48107 is a potent, selective positive allosteric modulator of G protein-coupled receptor 68 (GPR68), demonstrating specificity for GPR68 over closely related proton GPCRs, neurotransmitter transporters, and hERG ion ch...		Others
T29856	Aleplasinin	PAZ 417,PAZ417,PAZ-417	PAI-1
	Aleplasinin (PAZ 417) is a selective and orally active inhibitor of Plasminogen activator inhibitor-1(PAI-1) and a key negative regulator of the fibrinolytic system. Aleplasinin can be used in Alzheimer's disease studies...		PAI-1
T7476	AS057278	3-Methylpyrazole-5-carboxylic acid	Others
	AS057278 (3-Methylpyrazole-5-carboxylic acid) is an D-amino acid oxidase (DAAO) inhibitor.		Others
T4494	CLOZAPINE N-OXIDE		Dopamine Receptor , 5-HT Receptor , AChR , Drug Metabolite
	Clozapine N-oxide is the major metabolite of Clozapine and is blood-brain barrier permeable. Clozapine N-oxide is an agonist of DREADDs and activates the DREADD receptors hM3Dq and hM4Di. Clozapine N-oxide is also a dopa...		Dopamine Receptor , 5-HT Receptor , AChR , Drug Metabolite
T1628	Rivastigmine tartrate	SDZ-ENA 713,ENA 713	AChR , AChE
	Rivastigmine tartrate (SDZ-ENA 713) is a carbamate-derived reversible CHOLINESTERASE INHIBITOR that is selective for the CENTRAL NERVOUS SYSTEM and is used for the treatment of DEMENTIA in ALZHEIMER DISEASE and PARKINSON...		AChR , AChE
T8630	Baclofen hydrochloride	4-amino-3-(4-chlorophenyl)butanoic acid hydron chloride	GABA Receptor
	Baclofen hydrochloride (4-amino-3-(4-chlorophenyl)butanoic acid hydron chloride) is a GAMMA-AMINOBUTYRIC ACID derivative that is a specific GABA-B RECEPTORS agonist. It is used in the treatment of MUSCLE SPASTICITY, espe...		GABA Receptor
T7601L	Carbetocin acetate	Carbetocin acetate(37025-55-1 free base)	Oxytocin Receptor
	Carbetocin acetate is an obstetric drug used to control postpartum hemorrhage and bleeding after giving birth.		Oxytocin Receptor