aromatase — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T60022	Aromatase-IN-2		Others
	Aromatase-IN-2 has anti-inflammatory, antitumor and antiasthmatic effects.		Others
T60006	Aromatase inhibitor 23		Others
	Aromatase inhibitor 23 is an inhibitor that target protein-protein interactions in RAD51 family of recombinases.		Others
T61444	Nonsteroidal aromatase inhibitor 1
	Nonsteroidal aromatase inhibitor 1 (Compound 13h) effectively inhibits the enzyme CYP19A1 with an IC50 value of 0.09 nM. Due to its potent inhibitory activity, Nonsteroidal aromatase inhibitor 1 holds promise for researc...
T61463	Monoamine oxidase/Aromatase-IN-1
	Monoamine oxidase/Aromatase-IN-1 (compound 2q) is a potent dual inhibitor of monoamine oxidase (MAO) and aromatase, with IC50 values of 39 nM and 31 nM for MAO-B and aromatase, respectively. It holds significant potentia...
T7197	Fadrozole		Aromatase
	Fadrozole is a nonsteroidal aromatase inhibitor with potential antineoplastic activity(IC50 : 6.4 nM)		Aromatase
T7999	7-Hydroxyflavanone		Anti-infection
	7-Hydroxyflavanone shows antimicrobial activity against Streptococcus pneumoniae clinical isolates.		Anti-infection
T11991	Mefentrifluconazole		P450 , Antifungal
	Mefentrifluconazole is a potent, selective and orally active fungal CYP51 (Kd= 0.5 nM) inhibitor, but shows less inhibitory activity on human aromatase (IC50=0.92 μM). Mefentrifluconazole is a novel azole derivative and ...		P450 , Antifungal
T0393	Anastrozole	ZD1033	Aromatase
	Anastrozole (ZD1033)(ZD1033), a potent and highly selective aromatase (CYP19) inhibitor (IC50 = 15 nM), has no obvious effect on adrenocorticoid hormone synthesis.		Aromatase
T1590	Letrozole	CGS 20267	Aromatase , Autophagy
	Letrozole (CGS 20267) is an Aromatase Inhibitor. The mechanism of action of letrozole is as an Aromatase Inhibitor.		Aromatase , Autophagy
T7556	Fadrozole hydrochloride	CGS 16949A	Aromatase
	Fadrozole hydrochloride (CGS 16949A) is a model aromatase inhibitor that has been shown to suppress estrogen production in the ovaries of fish.		Aromatase
T1103	Aminoglutethimide	DL-Aminoglutethimide,BA-16038,NSC-330915	Aromatase
	Aminoglutethimide (BA-16038), an aromatase inhibitor, is used in the therapy of advanced BREAST Y.		Aromatase
T6917	Oleuropein		Apoptosis , Aromatase , ROS , PPAR
	Oleuropein is an antioxidant polyphenol isolated from olive leaf.		Apoptosis , Aromatase , ROS , PPAR
T2O2744	Alpha-Naphthoflavone	7,8-benzoflavone	Aromatase
	alpha-Naphthoflavone (7,8-benzoflavone), a synthetic flavonoid, is a potent inhibitor of aromatase with an I50 value of 0.5 μM.		Aromatase
T20625	Prochloraz	Sporgon,Prelude	Estrogen Receptor/ERR , AhR , Androgen Receptor , Antifungal
	Prochloraz (Prelude) is a broad-spectrum contact imidazole fungicide. Prochloraz inhibits human placental microsomal aromatase in vitro (IC50 = 40 nM). Prochloraz also acts as an estrogen receptor (IC50s = 25 μM) and and...
T1587	Exemestane	EXE,FCE 24304,PNU155971	Aromatase
	Exemestane (EXE) is an Aromatase Inhibitor. The mechanism of action of exemestane is as an Aromatase Inhibitor.		Aromatase
T0530	Flavanone	2-Phenyl-4-chromanone,4-Flavanone,2,3-Dihydroflavone,2-Phenylchroman-4-one	Others , Aromatase
	Flavanone (2-Phenylchroman-4-one)s from citrus fruits have also been shown to exert beneficial effects on human vascular function. In particular, chronic interventions with orange juice, or the pure flavanone hesperidin,...		Others , Aromatase
TN3987	Eriodictyol chalcone		Anti-infection , Aromatase
	Eriodictyol chalcone has anti-plasmodial effects on P. falciparum growth.		Anti-infection , Aromatase
T4281	Endoxifen	(E/Z)-N-desmethyl-4-hydroxy Tamoxifen,(E/Z)-Endoxifen	Estrogen Receptor/ERR , Aromatase , Estrogen/progestogen Receptor , Parasite , Drug Metabolite
	(E/Z)-Endoxifen ((E/Z)-Endoxifen) is an active metabolite of tamoxifen produced by the sequential action of cytochrome P450 (CYP) isoforms, including CYP2D6. It is a strong anti-estrogen, as it has an approximately 100-f...
T71708	Minamestane		Aromatase
	Minamestane is a novel irreversible aromatase inhibitor.Minamestane induces time-dependent inhibition of human placental aromatase with a half-life of 4 minutes and a K of 59 nM.Minamestane has antitumor activity.		Aromatase
T27320	Finrozole	MPV 2213ad,MPV-2213ad,MPV 2213,MPV-2213,MPV2213ad	Aromatase
	Finrozole (MPV 2213ad) is a novel selective aromatase inhibitor that is partially reversible for breast development.		Aromatase