ars — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T10376	ARS-1630		Ras
	ARS-1630 is a mutant K-ras G12C inhibitor. It is a less active enantiomer of ARS-1620.		Ras
T7414	ARS-853		Apoptosis , Raf , Ras
	ARS-853 is an inhibitor of K-RASG12C(IC50 : 2.5 μM), a mutant form of K-RAS that accumulates in the active GTP-bound state in certain cancer cells		Apoptosis , Raf , Ras
T10375	ARS-1323		Ras
	ARS-1323 is the racemate of ARS-1620 and a mutant K-ras G12C inhibitor.		Ras
T7609	ARS-1620		Ras
	ARS-1620 is a covalent inhibitor of K-RASG12C.		Ras
T14181	Alizarin Red S sodium	ARS sodium	Others
	Alizarin Red S sodium (ARS sodium) (ARS sodium) is an anthraquinone dye. Which has been widely used to evaluate calcium deposits in cell culture[1].		Others
T22249	1588-A4	ARS-1620 Intermediate	Ras
	1588-A4 (ARS-1620 Intermediate) is an intermediate of ARS-1620 which is an atropisomeric selective KRASG12C inhibitor with desirable pharmacokinetics.		Ras
T10374	ARS-1323-alkyne		Ras
	ARS-1323-alkyne is a switch-II pocket (S-IIP) inhibitor and a conformational specific chemical reporter of KRASG12C nucleotide state in living cells.		Ras
T73396	ARS-2102
	ARS-2102 is a potent covalent KRAS G12C inhibitor for use in cancer research .
T60538	SARS-CoV-2-IN-14	3',5-Dichlorosalicylanilide	SARS-CoV
	SARS-CoV-2-IN-14 is a potent and oral inhibitor of SARS-CoV-2 (IC50:0.39 μM), which is an analogue of niclosamide. SARS-CoV-2-IN-14 was more stable than niclosamide in the determination of human plasma and liver S9 enzym...		SARS-CoV
T77516	SARS-CoV-2-IN-39		Antiviral , SARS-CoV
	SARS-CoV-2-IN-39 is a SARS-CoV-2 inhibitor with an EC50 of 1 μM. SARS-CoV-2-IN-39 has antiviral activity and inhibits SARS-CoV-2 by inhibiting SKP2 protein and stabilizing BECN1.		Antiviral , SARS-CoV
T12367	Parsaclisib	INCB050465	PI3K
	Parsaclisib (INCB050465) is a potent and selective inhibitor of PI3Kδ(IC50 of 1 nM at 1 mM ATP)		PI3K
T60919	SARS-CoV-2-IN-13		SARS-CoV
	SARS-CoV-2-IN-13 (compound 5) is an analogue of niclosamide. SARS-CoV-2-IN-13 is more stable than niclosamide in human plasma and liver S9 enzymes assay. SARS-CoV-2-IN-13 can improve bioavailability and half-life when ad...		SARS-CoV
T27417L	Glutathione arsenoxide hydrochloride	GSAO HCl,Glutathione arsenoxide hydrochloride(1271726-51-2 Free base)	Apoptosis , AChR
	Glutathione arsenoxide hydrochloride (Glutathione arsenoxide hydrochloride(1271726-51-2 Free base)) is a potentially active anti-cancer molecule and inhibitor of tumour metabolism. glutathione arsenoxide hydrochloride ta...		Apoptosis , AChR
T2733	Sarsasapogenin	Parigenin,Sarsagenin	Apoptosis , NF-κB , Endogenous Metabolite
	Sarsasapogenin (Parigenin) is a steroidal sapogenin, that is the aglycosidic portion of a plant saponin. It is named after sarsaparilla (Smilax sp.), a family of climbing plants found in subtropical regions. It was one o...		Apoptosis , NF-κB , Endogenous Metabolite
T10358	Netarsudil Dihydrochloride	AR-13324 Dihydrochloride	ROCK
	Netarsudil Dihydrochloride (AR-13324 Dihydrochloride) is an inhibitor of Rho-associated protein kinase (ROCK) and norepinephrine transporter (NET) with effective in intraocular pressure (IOP) reduction.		ROCK
T5355	Sparsentan	RE-021,DARA-a	RAAS , Endothelin Receptor
	Sparsentan (DARA-a) is a first-in-class orally active and highly potent dual endothelin A and angiotensin II receptor antagonist(Ki of 9.3 and 0.8 nM, respectively)		RAAS , Endothelin Receptor
T76756	Parsatuzumab	RG 7414,Anti-EGFL7,MEGF0444A,MEGF-0444A,RO-5490248,M0444A	VEGFR
	Parsatuzumab (RG 7414) is a humanized monoclonal antibody targeting EGFL7, which is also used as an immunomodulator.Parsatuzumab selectively inhibits the interaction between EGFL7 and endothelial cells, and has an inhibi...		VEGFR
T76870	Narsoplimab	OMS 721	SARS-CoV
	Narsoplimab (OMS 721) is a selective whole-human immunoglobulin gamma-4 (IgG4) monoclonal antibody, a mannan-binding lectin-associated serine protease-2 (MASP-2) inhibitor that binds MASP-2 and prevents lectin pathway ac...		SARS-CoV
T78961	SARS-CoV-2-IN-38		SARS-CoV
	SARS-CoV-2-IN-38, also known as compound 24, is an inhibitor of SARS-CoV-2 that demonstrates favorable oral bioavailability in mice, with an absorption fraction of 39.75% [1].		SARS-CoV
T0258	Carsalam	Carsalame,Carbonylsalicylamide,2H-1,3-Benzoxazine-2,4(3H)-dione	Antibiotic
	Carsalam (2H-1,3-Benzoxazine-2,4(3H)-dione) is a nonsteroidal anti-inflammatory drug.		Antibiotic