Powder: -20°C for 3 years | In solvent: -80°C for 1 year
ARS-1620 is a covalent inhibitor of K-RASG12C.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 84.00 | |
2 mg | In stock | $ 119.00 | |
5 mg | In stock | $ 198.00 | |
10 mg | In stock | $ 289.00 | |
25 mg | In stock | $ 572.00 | |
50 mg | In stock | $ 822.00 | |
100 mg | In stock | $ 987.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 223.00 |
Description | ARS-1620 is a covalent inhibitor of K-RASG12C. |
In vivo | ARS-1620 (200 mg/kg) induces tumor regression in a MIA-PaCa2, but not an H441, mouse xenograft model.?It also decreases tumor volume in patient-derived xenograft (PDX) mouse models expressing K-RASG12C, but not K-RASG12D or wild-type K-RAS. |
Molecular Weight | 430.84 |
Formula | C21H17ClF2N4O2 |
CAS No. | 1698055-85-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 53 mg/mL (123.02 mM)
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
ARS-1620 1698055-85-4 GPCR/G Protein MAPK Ras inhibit Inhibitor ARS 1620 ARS1620 inhibitor