abc — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T23602	ABC99	ABC 99,ABC-99	Wnt/beta-catenin
	ABC99 is a selective irreversible inhibitor of the wnt-deacylating enzyme. ABC99 inhibited NOTUM (IC50: 13 nM). It also showed excellent selectivity across the serine hydrolase family.		Wnt/beta-catenin
T23601	ABC1183	ABC 1183,ABC-1183	GSK-3 , CDK
	ABC1183 is a novel diaminothiazole that inhibits GSK3α, GSK3β and CDK9. ABC1183 inhibits the growth of a numerous cancer cell lines by decreasing cell survival by inducing G2/M arrest and through altering GSK3, glycogen ...		GSK-3 , CDK
T6367	Abacavir sulfate	Abacavir Hemisulfate,1592U89,ABC sulfate,Ziagen	Apoptosis , HIV Protease , Reverse Transcriptase
	Abacavir sulfate (Ziagen) , a nucleoside analogue, effectively utilize its antiviral activity		Apoptosis , HIV Protease , Reverse Transcriptase
T6750	Opaganib	ABC294640	S1P Receptor
	Opaganib (ABC294640) is an orally active and specific sphingosine kinase-2 (SphK2) inhibitor (IC50: 60 μM).		S1P Receptor
T33648	Nestifylline	ABC 99,ABC99,ABC-99
	Nestifylline is a biochemical.
T80903	Ulviprubart	ABC-008
	Ulviprubart, an anti-KLRG1 monoclonal antibody (mAb), is utilized in various disease research [1].
T25611	Lanatoside	Lantoside,ABC lanatoside complex
	Lanatoside is an FDA-approved cardiac glycoside that has been identified as a candidate anti-dengue compound. It has also been found to promote atherosclerosis. It also has anti-tumor activity, inhibiting the growth of c...
T68352	ABC294735
	ABC294735 is a dual SK1/SK2 inhibitor with potential anticancer activity.
T38316	ABC34
	ABC34 is an inactive control probe for JJH260 , the inhibitor of androgen-induced gene 1 (AIG1), an enzyme that hydrolyzes fatty acid esters of hydroxy fatty acids (FAHFAs). ABC34 demonstrates an IC50 value greater than ...
T16040	Mepazine	Pecazine	Apoptosis , MALT
	Mepazine (Pecazine) is a potent and selective inhibitor of MALT1. Mepazine inhibits GSTMALT1 full length and GSTMALT1 325-760 with IC50s of 0.83 μM and 0.42 μM. Mepazine enhances apoptosis and affects the cell viability.		Apoptosis , MALT
T8596	Ceefourin 1		MRP
	Ceefourin 1 is a highly selective multidrug resistance protein 4 (MRP4) inhibitor.		MRP
T71299	M-25
	M-25 is a Smoothened antagonist and inhibitor of the Hedgehog pathway.
T5354	IRAK4-IN-7	CA-4948	IRAK
	IRAK4-IN-7 (CA-4948) is a selective and potent IRAK4 kinase inhibitor with in vivo activity in a TLR4-induced cytokine release model.		IRAK
T8491	Vorolanib	CM082,X-82	VEGFR , PDGFR
	Vorolanib (X-82) is an orally active VEGFR/PDGFR dual inhibitor.		VEGFR , PDGFR
T68135L	(Rac)-Sabcomeline HCl	sabcomeline HCl(149156-36-5 Free base)	AChR
	Sabcomeline HCl is an M1 receptor agonist that can be used to study Alzheimer's disease.		AChR
T18962	Dabcyl acid, SE	Dabcyl, SE	Others
	Dabcyl acid, SE (Dabcyl, SE) is the amino-reactive form of Dabcyl acid and used to prepare a variety of FRET-based probes that contain Dabcyl acid.		Others
T76844	Abciximab	C7E3	Integrin
	Abciximab (C7E3) is a mouse/human chimeric monoclonal antibody that is a potent glycoprotein IIb/IIIa inhibitor. Abciximab has anti-platelet aggregation and leukocyte adhesion, acting by binding to glycoproteins IIb/IIIa...		Integrin
T40303	5-A-RU-PABC-Val-Cit-Fmoc		Others
	5-A-RU-PABC-Val-Cit-Fmoc is one of the precursors of 5-A-RU, a small molecule mucosal-associated MAIT activator that is a precursor for bacterial synthesis of riboflavin.		Others
T18963	Dabcyl acid	DABCYL,Para-methyl red	Others
	Dabcyl acid (DABCYL) is the original dark fluorescence quencher.		Others
T3503	MC-Val-Cit-PABC-PNP	Maleimidocaproyl-L-valine-L-citrulline-p-aminobenzyl alcohol p-nitrophenyl carbonate	Others , AChR
	MC-Val-Cit-PABC-PNP, also known as Mc-Val-Cit-PABC-PNP, is a cathepsin cleavable ADC peptide linker. For example, FDA approved drug, brentuximab vedotin, adopts this linker. Protein- and peptide-drug conjugates hold a pr...		Others , AChR